1SQLA

Crystal structure of 7,8-dihydroneopterin aldolase in complex with guanine
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
120
structure length
120
Chain Sequence
GDKLILKGLKFYGFHGAIAEERTLGQMFLVDIDAWVSLKKAGESDNLEDTISYVDIFSLAKEIVEGSPRNLLETVAELIASKTLEKFHQINAVRVKLSKPNVALIKSTIDYLGVDIFRQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biosynthesis of Tetrahydrofolate in Plants: Crystal Structure of 7,8-Dihydroneopterin Aldolase from Arabidopsis thaliana Reveals a Novel Adolase Class.
pubmed doi rcsb
molecule keywords dihydroneopterin aldolase
molecule tags Lyase
total genus 31
structure length 120
sequence length 120
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
ec nomenclature ec 4.1.2.25: Dihydroneopterin aldolase.
pdb deposition date 2004-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02152 FolB Dihydroneopterin aldolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1130.10 Alpha Beta 2-Layer Sandwich GTP Cyclohydrolase I, domain 2 GTP Cyclohydrolase I, domain 2 1sqlA00
1GTPA 1WURA 1Z9WA 1RRWA 2O90A 3R2EA 3S19A 1RSDA 1A8RA 1RS4A 4UQFA 4AEYA 4FGCA 2NM3A 3BP1A 1B9LA 5F3MA 1DHNA 1RS2A 3O1KA 4IQIA 3UXJA 1FBXA 1NBUB 5FARA 1N3SA 3RJ4A 4F8BA 1IS8A 1N3RA 1WM9A 1U68A 4DU6A 3RZPA 1FB1A 1RSIA 1RRIA 2CG8A 1NBUC 2NM2A 1NBUA 1WPLA 3UXVA 3V9OA 2DHNA 1N3TA 4GHMA 1SQLA 1A9CA 1IS7A 1WUQA 1RRYA
chains in the Genus database with same CATH superfamily
1GTPA 1WURA 1Z9WA 1RRWA 2O90A 3R2EA 3S19A 1RSDA 1A8RA 1RS4A 4UQFA 4AEYA 4FGCA 2NM3A 3BP1A 1B9LA 5F3MA 1DHNA 1RS2A 3O1KA 4IQIA 3UXJA 1FBXA 1NBUB 5FARA 1N3SA 3RJ4A 4F8BA 1IS8A 1N3RA 1WM9A 1U68A 4DU6A 3RZPA 1FB1A 1RSIA 1RRIA 2CG8A 1NBUC 2NM2A 1NBUA 1WPLA 3UXVA 3V9OA 2DHNA 1N3TA 4GHMA 1SQLA 1A9CA 1IS7A 1WUQA 1RRYA
chains in the Genus database with same CATH topology
1GTPA 1WURA 1Z9WA 1RRWA 2O90A 3R2EA 3S19A 1RSDA 1A8RA 1RS4A 4UQFA 4AEYA 4FGCA 2NM3A 3BP1A 1B9LA 5F3MA 1DHNA 1RS2A 3O1KA 4IQIA 3UXJA 1FBXA 1NBUB 5FARA 1N3SA 3RJ4A 4F8BA 1IS8A 1N3RA 1WM9A 1U68A 4DU6A 3RZPA 1FB1A 1RSIA 1RRIA 2CG8A 1NBUC 2NM2A 1NBUA 1WPLA 3UXVA 3V9OA 2DHNA 1N3TA 4GHMA 1SQLA 1A9CA 1IS7A 1WUQA 1RRYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GTP A;  1WUR A;  1Z9W A;  1RRW A;  2O90 A;  3R2E A;  3S19 A;  1RSD A;  1A8R A;  1RS4 A;  4UQF A;  4AEY A;  4FGC A;  2NM3 A;  3BP1 A;  1B9L A;  5F3M A;  1DHN A;  1RS2 A;  3O1K A;  4IQI A;  3UXJ A;  1FBX A;  1NBU B;  5FAR A;  1N3S A;  3RJ4 A;  4F8B A;  1IS8 A;  1N3R A;  1WM9 A;  1U68 A;  4DU6 A;  3RZP A;  1FB1 A;  1RSI A;  1RRI A;  2CG8 A;  1NBU C;  2NM2 A;  1NBU A;  1WPL A;  3UXV A;  3V9O A;  2DHN A;  1N3T A;  4GHM A;  1SQL A;  1A9C A;  1IS7 A;  1WUQ A;  1RRY A; 
#chains in the Genus database with same CATH topology
 1GTP A;  1WUR A;  1Z9W A;  1RRW A;  2O90 A;  3R2E A;  3S19 A;  1RSD A;  1A8R A;  1RS4 A;  4UQF A;  4AEY A;  4FGC A;  2NM3 A;  3BP1 A;  1B9L A;  5F3M A;  1DHN A;  1RS2 A;  3O1K A;  4IQI A;  3UXJ A;  1FBX A;  1NBU B;  5FAR A;  1N3S A;  3RJ4 A;  4F8B A;  1IS8 A;  1N3R A;  1WM9 A;  1U68 A;  4DU6 A;  3RZP A;  1FB1 A;  1RSI A;  1RRI A;  2CG8 A;  1NBU C;  2NM2 A;  1NBU A;  1WPL A;  3UXV A;  3V9O A;  2DHN A;  1N3T A;  4GHM A;  1SQL A;  1A9C A;  1IS7 A;  1WUQ A;  1RRY A; 
#chains in the Genus database with same CATH homology
 1GTP A;  1WUR A;  1Z9W A;  1RRW A;  2O90 A;  3R2E A;  3S19 A;  1RSD A;  1A8R A;  1RS4 A;  4UQF A;  4AEY A;  4FGC A;  2NM3 A;  3BP1 A;  1B9L A;  5F3M A;  1DHN A;  1RS2 A;  3O1K A;  4IQI A;  3UXJ A;  1FBX A;  1NBU B;  5FAR A;  1N3S A;  3RJ4 A;  4F8B A;  1IS8 A;  1N3R A;  1WM9 A;  1U68 A;  4DU6 A;  3RZP A;  1FB1 A;  1RSI A;  1RRI A;  2CG8 A;  1NBU C;  2NM2 A;  1NBU A;  1WPL A;  3UXV A;  3V9O A;  2DHN A;  1N3T A;  4GHM A;  1SQL A;  1A9C A;  1IS7 A;  1WUQ A;  1RRY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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