1TX4A

Rho/rhogap/gdp(dot)alf4 complex
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
196
structure length
196
Chain Sequence
PLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNALHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue.
pubmed doi rcsb
molecule tags Complex(gtpase activatn/proto-oncogene)
source organism Homo sapiens
molecule keywords P50-RHOGAP
total genus 72
structure length 196
sequence length 196
ec nomenclature
pdb deposition date 1997-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1tx4A00
3FK2A 3CXLA 2MBGA 5JCPA 5HPYA 3KUQA 3W6RA 5C5SA 3IUGA 3MSXB 2NGRB 3QISA 2OSAA 3WPSA 1F7CA 1OW3A 1TX4A 1GRNB 5IRCA 3EAPA 2EE5A 1PBWA 5C2JA 1AM4A 2OVJA 3WPQA 1XA6A 2EE4A 5JD0A 3BYIA 1RGPA 2XS6A 2QV2A
chains in the Genus database with same CATH superfamily
3FK2A 3CXLA 2MBGA 5JCPA 5HPYA 3KUQA 3W6RA 5C5SA 3IUGA 3MSXB 2NGRB 3QISA 2OSAA 3WPSA 1F7CA 1OW3A 1TX4A 1GRNB 5IRCA 3EAPA 2EE5A 1PBWA 5C2JA 1AM4A 2OVJA 3WPQA 1XA6A 2EE4A 5JD0A 3BYIA 1RGPA 2XS6A 2QV2A
chains in the Genus database with same CATH topology
3FK2A 3CXLA 2MBGA 5JCPA 5HPYA 3KUQA 3W6RA 5C5SA 3IUGA 3MSXB 2NGRB 3QISA 2OSAA 3WPSA 1F7CA 1OW3A 1TX4A 1GRNB 5IRCA 3EAPA 2EE5A 1PBWA 5C2JA 1AM4A 2OVJA 3WPQA 1XA6A 2EE4A 5JD0A 3BYIA 1RGPA 2XS6A 2QV2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FK2 A;  3CXL A;  2MBG A;  5JCP A;  5HPY A;  3KUQ A;  3W6R A;  5C5S A;  3IUG A;  3MSX B;  2NGR B;  3QIS A;  2OSA A;  3WPS A;  1F7C A;  1OW3 A;  1TX4 A;  1GRN B;  5IRC A;  3EAP A;  2EE5 A;  1PBW A;  5C2J A;  1AM4 A;  2OVJ A;  3WPQ A;  1XA6 A;  2EE4 A;  5JD0 A;  3BYI A;  1RGP A;  2XS6 A;  2QV2 A; 
#chains in the Genus database with same CATH topology
 3FK2 A;  3CXL A;  2MBG A;  5JCP A;  5HPY A;  3KUQ A;  3W6R A;  5C5S A;  3IUG A;  3MSX B;  2NGR B;  3QIS A;  2OSA A;  3WPS A;  1F7C A;  1OW3 A;  1TX4 A;  1GRN B;  5IRC A;  3EAP A;  2EE5 A;  1PBW A;  5C2J A;  1AM4 A;  2OVJ A;  3WPQ A;  1XA6 A;  2EE4 A;  5JD0 A;  3BYI A;  1RGP A;  2XS6 A;  2QV2 A; 
#chains in the Genus database with same CATH homology
 3FK2 A;  3CXL A;  2MBG A;  5JCP A;  5HPY A;  3KUQ A;  3W6R A;  5C5S A;  3IUG A;  3MSX B;  2NGR B;  3QIS A;  2OSA A;  3WPS A;  1F7C A;  1OW3 A;  1TX4 A;  1GRN B;  5IRC A;  3EAP A;  2EE5 A;  1PBW A;  5C2J A;  1AM4 A;  2OVJ A;  3WPQ A;  1XA6 A;  2EE4 A;  5JD0 A;  3BYI A;  1RGP A;  2XS6 A;  2QV2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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