1TX4 | Genus

Total Genus 72

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	72
sequence length	196
structure length	196
Chain Sequence	PLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNALHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 196 atoms

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196 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue. pubmed doi rcsb
molecule keywords	P50-RHOGAP
molecule tags	Complex(gtpase activatn/proto-oncogene)
source organism	Homo sapiens
total genus	72
structure length	196
sequence length	196
ec nomenclature
pdb deposition date	1997-07-29

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00620	RhoGAP	RhoGAP domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.555.10	Mainly Alpha	Orthogonal Bundle	Phosphatidylinositol 3-kinase; Chain A	Rho GTPase activation protein	1tx4A00

5JCPA 2QV2A 1TX4A 5HPYA 3CXLA 3EAPA 3QISA 1OW3A 2MBGA 1GRNB 1RGPA 2XS6A 3MSXB 2NGRB 3IUGA 5JD0A 5IRCA 2EE5A 3FK2A 1XA6A 2OVJA 2EE4A 3KUQA 3BYIA 2OSAA 5C5SA 3WPSA 1PBWA 3W6RA 3WPQA 1AM4A 5C2JA 1F7CA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5JCP A;  2QV2 A;  1TX4 A;  5HPY A;  3CXL A;  3EAP A;  3QIS A;  1OW3 A;  2MBG A;  1GRN B;  1RGP A;  2XS6 A;  3MSX B;  2NGR B;  3IUG A;  5JD0 A;  5IRC A;  2EE5 A;  3FK2 A;  1XA6 A;  2OVJ A;  2EE4 A;  3KUQ A;  3BYI A;  2OSA A;  5C5S A;  3WPS A;  1PBW A;  3W6R A;  3WPQ A;  1AM4 A;  5C2J A;  1F7C A; 
#chains in the Genus database with same CATH topology
 5JCP A;  2QV2 A;  1TX4 A;  5HPY A;  3CXL A;  3EAP A;  3QIS A;  1OW3 A;  2MBG A;  1GRN B;  1RGP A;  2XS6 A;  3MSX B;  2NGR B;  3IUG A;  5JD0 A;  5IRC A;  2EE5 A;  3FK2 A;  1XA6 A;  2OVJ A;  2EE4 A;  3KUQ A;  3BYI A;  2OSA A;  5C5S A;  3WPS A;  1PBW A;  3W6R A;  3WPQ A;  1AM4 A;  5C2J A;  1F7C A; 
#chains in the Genus database with same CATH homology
 5JCP A;  2QV2 A;  1TX4 A;  5HPY A;  3CXL A;  3EAP A;  3QIS A;  1OW3 A;  2MBG A;  1GRN B;  1RGP A;  2XS6 A;  3MSX B;  2NGR B;  3IUG A;  5JD0 A;  5IRC A;  2EE5 A;  3FK2 A;  1XA6 A;  2OVJ A;  2EE4 A;  3KUQ A;  3BYI A;  2OSA A;  5C5S A;  3WPS A;  1PBW A;  3W6R A;  3WPQ A;  1AM4 A;  5C2J A;  1F7C A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1TX4A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations