1YI2K

Crystal structure of erythromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
132
structure length
132
Chain Sequence
MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRLPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 29
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2005-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 1yi2K00
1YJ9K 3CC7K 2OTLK 3J7YL 1QVFJ 1VQMK 1VQPK 5DM7H 5HL7H 3PIPH 1YIJK 3CCLK 2ZJPH 1VQ7K 1VQNK 1YJNK 1VQ6K 4IOCH 3I55K 1Q7YL 1S72K 4U67H 3G4SK 1VQKK 1M90L 2OTJK 3CCSK 5JVHH 1YITK 3I56K 3CXCJ 1NJIL 5MLCM 1KQSJ 5GAHL 1JJ2J 3CCJK 2QEXK 1W2BJ 3DLLH 3PIOH 1VQ9K 1YI2K 3OW2J 3J7ZK 1Q86L 1YHQK 3CCQK 3CPWJ 1VQ4K 4WFNH 3CCVK 5GADL 3CCMK 3G6EK 2ZJRH 4WFBH 5AN9E 1K9ML 1VQ8K 3CCEK 3CC2K 1K8AL 5GAEL 3CMEK 1VQ5K 3CCRK 1QVGJ 4IO9H 1YJWK 4WF9H 4V19O 1KD1L 3CF5H 4WCEH 1Q81L 5GAGL 5JVGH 1Q82L 5H1SM 3CMAK 4UY8K 3CD6K 1N8RL 1M1KL 4IOAH 1WHIA 3CC4K 5DM6H 2ZJQH 4WFAH 3G71K 1KC8L 1VQOK 1VQLK 1K73L 3CCUK 2QA4K
chains in the Genus database with same CATH superfamily
1YJ9K 3CC7K 2OTLK 3J7YL 1QVFJ 1VQMK 1VQPK 5DM7H 5HL7H 3PIPH 1YIJK 3CCLK 2ZJPH 1VQ7K 1VQNK 1YJNK 1VQ6K 4IOCH 3I55K 1Q7YL 1S72K 4U67H 3G4SK 1VQKK 1M90L 2OTJK 3CCSK 5JVHH 1YITK 3I56K 3CXCJ 1NJIL 5MLCM 1KQSJ 5GAHL 1JJ2J 3CCJK 2QEXK 1W2BJ 3DLLH 3PIOH 1VQ9K 1YI2K 3OW2J 3J7ZK 1Q86L 1YHQK 3CCQK 3CPWJ 1VQ4K 4WFNH 3CCVK 5GADL 3CCMK 3G6EK 2ZJRH 4WFBH 5AN9E 1K9ML 1VQ8K 3CCEK 3CC2K 1K8AL 5GAEL 3CMEK 1VQ5K 3CCRK 1QVGJ 4IO9H 1YJWK 4WF9H 4V19O 1KD1L 3CF5H 4WCEH 1Q81L 5GAGL 5JVGH 1Q82L 5H1SM 3CMAK 4UY8K 3CD6K 1N8RL 1M1KL 4IOAH 1WHIA 3CC4K 5DM6H 2ZJQH 4WFAH 3G71K 1KC8L 1VQOK 1VQLK 1K73L 3CCUK 2QA4K
chains in the Genus database with same CATH topology
1YJ9K 3CC7K 2OTLK 3J7YL 1QVFJ 1VQMK 1VQPK 5DM7H 5HL7H 3PIPH 1YIJK 3CCLK 2ZJPH 1VQ7K 1VQNK 1YJNK 1VQ6K 4IOCH 3I55K 1Q7YL 1S72K 4U67H 3G4SK 1VQKK 1M90L 2OTJK 3CCSK 5JVHH 1YITK 3I56K 3CXCJ 1NJIL 5MLCM 1KQSJ 5GAHL 1JJ2J 3CCJK 2QEXK 1W2BJ 3DLLH 3PIOH 1VQ9K 1YI2K 3OW2J 3J7ZK 1Q86L 1YHQK 3CCQK 3CPWJ 1VQ4K 4WFNH 3CCVK 5GADL 3CCMK 3G6EK 2ZJRH 4WFBH 5AN9E 1K9ML 1VQ8K 3CCEK 3CC2K 1K8AL 5GAEL 3CMEK 1VQ5K 3CCRK 1QVGJ 4IO9H 1YJWK 4WF9H 4V19O 1KD1L 3CF5H 4WCEH 1Q81L 5GAGL 5JVGH 1Q82L 5H1SM 3CMAK 4UY8K 3CD6K 1N8RL 1M1KL 4IOAH 1WHIA 3CC4K 5DM6H 2ZJQH 4WFAH 3G71K 1KC8L 1VQOK 1VQLK 1K73L 3CCUK 2QA4K
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YJ9 K;  3CC7 K;  2OTL K;  3J7Y L;  1QVF J;  1VQM K;  1VQP K;  5DM7 H;  5HL7 H;  3PIP H;  1YIJ K;  3CCL K;  2ZJP H;  1VQ7 K;  1VQN K;  1YJN K;  1VQ6 K;  4IOC H;  3I55 K;  1Q7Y L;  1S72 K;  4U67 H;  3G4S K;  1VQK K;  1M90 L;  2OTJ K;  3CCS K;  5JVH H;  1YIT K;  3I56 K;  3CXC J;  1NJI L;  5MLC M;  1KQS J;  5GAH L;  1JJ2 J;  3CCJ K;  2QEX K;  1W2B J;  3DLL H;  3PIO H;  1VQ9 K;  1YI2 K;  3OW2 J;  3J7Z K;  1Q86 L;  1YHQ K;  3CCQ K;  3CPW J;  1VQ4 K;  4WFN H;  3CCV K;  5GAD L;  3CCM K;  3G6E K;  2ZJR H;  4WFB H;  5AN9 E;  1K9M L;  1VQ8 K;  3CCE K;  3CC2 K;  1K8A L;  5GAE L;  3CME K;  1VQ5 K;  3CCR K;  1QVG J;  4IO9 H;  1YJW K;  4WF9 H;  4V19 O;  1KD1 L;  3CF5 H;  4WCE H;  1Q81 L;  5GAG L;  5JVG H;  1Q82 L;  5H1S M;  3CMA K;  4UY8 K;  3CD6 K;  1N8R L;  1M1K L;  4IOA H;  1WHI A;  3CC4 K;  5DM6 H;  2ZJQ H;  4WFA H;  3G71 K;  1KC8 L;  1VQO K;  1VQL K;  1K73 L;  3CCU K;  2QA4 K; 
#chains in the Genus database with same CATH topology
 1YJ9 K;  3CC7 K;  2OTL K;  3J7Y L;  1QVF J;  1VQM K;  1VQP K;  5DM7 H;  5HL7 H;  3PIP H;  1YIJ K;  3CCL K;  2ZJP H;  1VQ7 K;  1VQN K;  1YJN K;  1VQ6 K;  4IOC H;  3I55 K;  1Q7Y L;  1S72 K;  4U67 H;  3G4S K;  1VQK K;  1M90 L;  2OTJ K;  3CCS K;  5JVH H;  1YIT K;  3I56 K;  3CXC J;  1NJI L;  5MLC M;  1KQS J;  5GAH L;  1JJ2 J;  3CCJ K;  2QEX K;  1W2B J;  3DLL H;  3PIO H;  1VQ9 K;  1YI2 K;  3OW2 J;  3J7Z K;  1Q86 L;  1YHQ K;  3CCQ K;  3CPW J;  1VQ4 K;  4WFN H;  3CCV K;  5GAD L;  3CCM K;  3G6E K;  2ZJR H;  4WFB H;  5AN9 E;  1K9M L;  1VQ8 K;  3CCE K;  3CC2 K;  1K8A L;  5GAE L;  3CME K;  1VQ5 K;  3CCR K;  1QVG J;  4IO9 H;  1YJW K;  4WF9 H;  4V19 O;  1KD1 L;  3CF5 H;  4WCE H;  1Q81 L;  5GAG L;  5JVG H;  1Q82 L;  5H1S M;  3CMA K;  4UY8 K;  3CD6 K;  1N8R L;  1M1K L;  4IOA H;  1WHI A;  3CC4 K;  5DM6 H;  2ZJQ H;  4WFA H;  3G71 K;  1KC8 L;  1VQO K;  1VQL K;  1K73 L;  3CCU K;  2QA4 K; 
#chains in the Genus database with same CATH homology
 1YJ9 K;  3CC7 K;  2OTL K;  3J7Y L;  1QVF J;  1VQM K;  1VQP K;  5DM7 H;  5HL7 H;  3PIP H;  1YIJ K;  3CCL K;  2ZJP H;  1VQ7 K;  1VQN K;  1YJN K;  1VQ6 K;  4IOC H;  3I55 K;  1Q7Y L;  1S72 K;  4U67 H;  3G4S K;  1VQK K;  1M90 L;  2OTJ K;  3CCS K;  5JVH H;  1YIT K;  3I56 K;  3CXC J;  1NJI L;  5MLC M;  1KQS J;  5GAH L;  1JJ2 J;  3CCJ K;  2QEX K;  1W2B J;  3DLL H;  3PIO H;  1VQ9 K;  1YI2 K;  3OW2 J;  3J7Z K;  1Q86 L;  1YHQ K;  3CCQ K;  3CPW J;  1VQ4 K;  4WFN H;  3CCV K;  5GAD L;  3CCM K;  3G6E K;  2ZJR H;  4WFB H;  5AN9 E;  1K9M L;  1VQ8 K;  3CCE K;  3CC2 K;  1K8A L;  5GAE L;  3CME K;  1VQ5 K;  3CCR K;  1QVG J;  4IO9 H;  1YJW K;  4WF9 H;  4V19 O;  1KD1 L;  3CF5 H;  4WCE H;  1Q81 L;  5GAG L;  5JVG H;  1Q82 L;  5H1S M;  3CMA K;  4UY8 K;  3CD6 K;  1N8R L;  1M1K L;  4IOA H;  1WHI A;  3CC4 K;  5DM6 H;  2ZJQ H;  4WFA H;  3G71 K;  1KC8 L;  1VQO K;  1VQL K;  1K73 L;  3CCU K;  2QA4 K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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