2BETA

Structure of mycobacterium tuberculosis ribose-5-phosphate isomerase, rpib, rv2465c, in complex with 4-phospho-d-erythronate.
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
157
structure length
157
Chain Sequence
GMRVYLGADHAGYELKQRIIEHLKQTGHEPIDCGALRYDADDDYPAFCIAAATRTVADPGSLGIVLGGSGNGEQIAANKVPGARCALAWSVQTAALAREHNNAQLIGIGGRMHTVAEALAIVDAFVTTPWSKAQRHQRRIDILAEYERTHEAPPVPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
molecule keywords CARBOHYDRATE-PHOSPHATE ISOMERASE
publication title Competitive Inhibitors of Mycobacterium Tuberculosis Ribose-5-Phosphate Isomerase B Reveal New Information About the Reaction Mechanism
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 53
structure length 157
sequence length 157
chains with identical sequence B, C, D, E
ec nomenclature ec 5.3.1.6: Ribose-5-phosphate isomerase.
pdb deposition date 2004-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02502 LacAB_rpiB Ribose/Galactose Isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1400.10 Alpha Beta 3-Layer(aba) Sandwich Ribose 5-phosphate Isomerase B; Chain: A, Sugar-phosphate isomerase, RpiB/LacA/LacB 2betA00
4LFKB 4LFKA 3ONOA 5IFZA 3PH4A 3SGWA 1USLA 2PPWA 2VVPA 2VVRA 3K7PA 4EM8A 4LFMB 4LFMA 3K8CA 3S5PA 3M1PA 4LFLA 1O1XA 3HEEA 4LFLB 2VVQA 2VVOA 3QD5A 3PH3A 3K7OA 2BETA 1NN4A 4LFNB 4LFNA 4U8FA 2BESA 3K7SA 3HE8A 4U8EA 3C5YA 3SDWA
chains in the Genus database with same CATH superfamily
4LFKB 4LFKA 3ONOA 5IFZA 3PH4A 3SGWA 1USLA 2PPWA 2VVPA 2VVRA 3K7PA 4EM8A 4LFMB 4LFMA 3K8CA 3S5PA 3M1PA 4LFLA 1O1XA 3HEEA 4LFLB 2VVQA 2VVOA 3QD5A 3PH3A 3K7OA 2BETA 1NN4A 4LFNB 4LFNA 4U8FA 2BESA 3K7SA 3HE8A 4U8EA 3C5YA 3SDWA
chains in the Genus database with same CATH topology
4LFKB 4LFKA 3ONOA 5IFZA 3PH4A 3SGWA 1USLA 2PPWA 2VVPA 2VVRA 3K7PA 4EM8A 4LFMB 4LFMA 3K8CA 3S5PA 3M1PA 4LFLA 1O1XA 3HEEA 4LFLB 2VVQA 2VVOA 3QD5A 3PH3A 3K7OA 2BETA 1NN4A 4LFNB 4LFNA 4U8FA 2BESA 3K7SA 3HE8A 4U8EA 3C5YA 3SDWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LFK B;  4LFK A;  3ONO A;  5IFZ A;  3PH4 A;  3SGW A;  1USL A;  2PPW A;  2VVP A;  2VVR A;  3K7P A;  4EM8 A;  4LFM B;  4LFM A;  3K8C A;  3S5P A;  3M1P A;  4LFL A;  1O1X A;  3HEE A;  4LFL B;  2VVQ A;  2VVO A;  3QD5 A;  3PH3 A;  3K7O A;  2BET A;  1NN4 A;  4LFN B;  4LFN A;  4U8F A;  2BES A;  3K7S A;  3HE8 A;  4U8E A;  3C5Y A;  3SDW A; 
#chains in the Genus database with same CATH topology
 4LFK B;  4LFK A;  3ONO A;  5IFZ A;  3PH4 A;  3SGW A;  1USL A;  2PPW A;  2VVP A;  2VVR A;  3K7P A;  4EM8 A;  4LFM B;  4LFM A;  3K8C A;  3S5P A;  3M1P A;  4LFL A;  1O1X A;  3HEE A;  4LFL B;  2VVQ A;  2VVO A;  3QD5 A;  3PH3 A;  3K7O A;  2BET A;  1NN4 A;  4LFN B;  4LFN A;  4U8F A;  2BES A;  3K7S A;  3HE8 A;  4U8E A;  3C5Y A;  3SDW A; 
#chains in the Genus database with same CATH homology
 4LFK B;  4LFK A;  3ONO A;  5IFZ A;  3PH4 A;  3SGW A;  1USL A;  2PPW A;  2VVP A;  2VVR A;  3K7P A;  4EM8 A;  4LFM B;  4LFM A;  3K8C A;  3S5P A;  3M1P A;  4LFL A;  1O1X A;  3HEE A;  4LFL B;  2VVQ A;  2VVO A;  3QD5 A;  3PH3 A;  3K7O A;  2BET A;  1NN4 A;  4LFN B;  4LFN A;  4U8F A;  2BES A;  3K7S A;  3HE8 A;  4U8E A;  3C5Y A;  3SDW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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