2VVPA

Crystal structure of mycobacterium tuberculosis ribose-5-phosphate isomerase b in complex with its substrates ribose 5-phosphate and ribulose 5-phosphate
Total Genus 57
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
157
structure length
157
Chain Sequence
GMRVYLGADHAGYELKQRIIEHLKQTGHEPIDCGALRYDADDDYPAFCIAAATRTVADPGSLGIVLGGSGNGEQIAANKVPGARCALAWSVQTAALAREHNNAQLIGIGGRMHTVAEALAIVDAFVTTPWSKAQRHQRRIDILAEYERTHEAPPVPG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Isomerase
molecule keywords RIBOSE-5-PHOSPHATE ISOMERASE B
publication title D-Ribose-5-Phosphate Isomerase B from Escherichia Coli is Also a Functional D-Allose-6-Phosphate Isomerase, While the Mycobacterium Tuberculosis Enzyme is not.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 57
structure length 157
sequence length 157
chains with identical sequence B, C, D, E
ec nomenclature ec 5.3.1.6: Ribose-5-phosphate isomerase.
pdb deposition date 2008-06-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02502 LacAB_rpiB Ribose/Galactose Isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1400.10 Alpha Beta 3-Layer(aba) Sandwich Ribose 5-phosphate Isomerase B; Chain: A, Sugar-phosphate isomerase, RpiB/LacA/LacB 2vvpA00
3S5PA 4LFMB 3QD5A 4LFKB 4LFNB 2PPWA 3ONOA 3PH4A 3M1PA 4LFMA 3PH3A 4EM8A 2BESA 2VVQA 4LFKA 4LFNA 3SGWA 1NN4A 3SDWA 2BETA 3K7OA 2VVPA 5IFZA 4LFLB 3C5YA 3K7PA 3K7SA 3K8CA 4U8FA 3HE8A 1USLA 2VVOA 4U8EA 4LFLA 3HEEA 2VVRA 1O1XA
chains in the Genus database with same CATH superfamily
3S5PA 4LFMB 3QD5A 4LFKB 4LFNB 2PPWA 3ONOA 3PH4A 3M1PA 4LFMA 3PH3A 4EM8A 2BESA 2VVQA 4LFKA 4LFNA 3SGWA 1NN4A 3SDWA 2BETA 3K7OA 2VVPA 5IFZA 4LFLB 3C5YA 3K7PA 3K7SA 3K8CA 4U8FA 3HE8A 1USLA 2VVOA 4U8EA 4LFLA 3HEEA 2VVRA 1O1XA
chains in the Genus database with same CATH topology
3S5PA 4LFMB 3QD5A 4LFKB 4LFNB 2PPWA 3ONOA 3PH4A 3M1PA 4LFMA 3PH3A 4EM8A 2BESA 2VVQA 4LFKA 4LFNA 3SGWA 1NN4A 3SDWA 2BETA 3K7OA 2VVPA 5IFZA 4LFLB 3C5YA 3K7PA 3K7SA 3K8CA 4U8FA 3HE8A 1USLA 2VVOA 4U8EA 4LFLA 3HEEA 2VVRA 1O1XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S5P A;  4LFM B;  3QD5 A;  4LFK B;  4LFN B;  2PPW A;  3ONO A;  3PH4 A;  3M1P A;  4LFM A;  3PH3 A;  4EM8 A;  2BES A;  2VVQ A;  4LFK A;  4LFN A;  3SGW A;  1NN4 A;  3SDW A;  2BET A;  3K7O A;  2VVP A;  5IFZ A;  4LFL B;  3C5Y A;  3K7P A;  3K7S A;  3K8C A;  4U8F A;  3HE8 A;  1USL A;  2VVO A;  4U8E A;  4LFL A;  3HEE A;  2VVR A;  1O1X A; 
#chains in the Genus database with same CATH topology
 3S5P A;  4LFM B;  3QD5 A;  4LFK B;  4LFN B;  2PPW A;  3ONO A;  3PH4 A;  3M1P A;  4LFM A;  3PH3 A;  4EM8 A;  2BES A;  2VVQ A;  4LFK A;  4LFN A;  3SGW A;  1NN4 A;  3SDW A;  2BET A;  3K7O A;  2VVP A;  5IFZ A;  4LFL B;  3C5Y A;  3K7P A;  3K7S A;  3K8C A;  4U8F A;  3HE8 A;  1USL A;  2VVO A;  4U8E A;  4LFL A;  3HEE A;  2VVR A;  1O1X A; 
#chains in the Genus database with same CATH homology
 3S5P A;  4LFM B;  3QD5 A;  4LFK B;  4LFN B;  2PPW A;  3ONO A;  3PH4 A;  3M1P A;  4LFM A;  3PH3 A;  4EM8 A;  2BES A;  2VVQ A;  4LFK A;  4LFN A;  3SGW A;  1NN4 A;  3SDW A;  2BET A;  3K7O A;  2VVP A;  5IFZ A;  4LFL B;  3C5Y A;  3K7P A;  3K7S A;  3K8C A;  4U8F A;  3HE8 A;  1USL A;  2VVO A;  4U8E A;  4LFL A;  3HEE A;  2VVR A;  1O1X A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...