3K7PA

Structure of mutant of ribose 5-phosphate isomerase type b from trypanosoma cruzi.
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
153
structure length
153
Chain Sequence
MTRRVAIGTDHPAFAIHENLILYVKEAGDEFVPVYCGPKTAESVDYPDFASRVAEMVARKEVEFGVLAAGSGIGMSIAANKVPGVRAALCHDHYTAAMSRIHNDANIVCVGERTTGVEVIREIIITFLQTPFSGEERHVRRIEKIRAIEASHA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
molecule keywords Ribose 5-phosphate isomerase
publication title Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family.
pubmed doi rcsb
source organism Trypanosoma cruzi
total genus 58
structure length 153
sequence length 153
chains with identical sequence B
ec nomenclature ec 5.3.1.6: Ribose-5-phosphate isomerase.
pdb deposition date 2009-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02502 LacAB_rpiB Ribose/Galactose Isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1400.10 Alpha Beta 3-Layer(aba) Sandwich Ribose 5-phosphate Isomerase B; Chain: A, Sugar-phosphate isomerase, RpiB/LacA/LacB 3k7pA00
1USLA 3K7OA 2BETA 4LFNA 1NN4A 4LFNB 3K7PA 4LFKB 3ONOA 2VVRA 3QD5A 4EM8A 2BESA 4U8EA 2VVQA 4U8FA 3S5PA 3HE8A 1O1XA 2VVOA 5IFZA 2VVPA 3K7SA 3PH4A 3PH3A 2PPWA 3M1PA 4LFMA 4LFKA 4LFLA 3C5YA 3SDWA 4LFMB 3SGWA 3HEEA 3K8CA 4LFLB
chains in the Genus database with same CATH superfamily
1USLA 3K7OA 2BETA 4LFNA 1NN4A 4LFNB 3K7PA 4LFKB 3ONOA 2VVRA 3QD5A 4EM8A 2BESA 4U8EA 2VVQA 4U8FA 3S5PA 3HE8A 1O1XA 2VVOA 5IFZA 2VVPA 3K7SA 3PH4A 3PH3A 2PPWA 3M1PA 4LFMA 4LFKA 4LFLA 3C5YA 3SDWA 4LFMB 3SGWA 3HEEA 3K8CA 4LFLB
chains in the Genus database with same CATH topology
1USLA 3K7OA 2BETA 4LFNA 1NN4A 4LFNB 3K7PA 4LFKB 3ONOA 2VVRA 3QD5A 4EM8A 2BESA 4U8EA 2VVQA 4U8FA 3S5PA 3HE8A 1O1XA 2VVOA 5IFZA 2VVPA 3K7SA 3PH4A 3PH3A 2PPWA 3M1PA 4LFMA 4LFKA 4LFLA 3C5YA 3SDWA 4LFMB 3SGWA 3HEEA 3K8CA 4LFLB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1USL A;  3K7O A;  2BET A;  4LFN A;  1NN4 A;  4LFN B;  3K7P A;  4LFK B;  3ONO A;  2VVR A;  3QD5 A;  4EM8 A;  2BES A;  4U8E A;  2VVQ A;  4U8F A;  3S5P A;  3HE8 A;  1O1X A;  2VVO A;  5IFZ A;  2VVP A;  3K7S A;  3PH4 A;  3PH3 A;  2PPW A;  3M1P A;  4LFM A;  4LFK A;  4LFL A;  3C5Y A;  3SDW A;  4LFM B;  3SGW A;  3HEE A;  3K8C A;  4LFL B; 
#chains in the Genus database with same CATH topology
 1USL A;  3K7O A;  2BET A;  4LFN A;  1NN4 A;  4LFN B;  3K7P A;  4LFK B;  3ONO A;  2VVR A;  3QD5 A;  4EM8 A;  2BES A;  4U8E A;  2VVQ A;  4U8F A;  3S5P A;  3HE8 A;  1O1X A;  2VVO A;  5IFZ A;  2VVP A;  3K7S A;  3PH4 A;  3PH3 A;  2PPW A;  3M1P A;  4LFM A;  4LFK A;  4LFL A;  3C5Y A;  3SDW A;  4LFM B;  3SGW A;  3HEE A;  3K8C A;  4LFL B; 
#chains in the Genus database with same CATH homology
 1USL A;  3K7O A;  2BET A;  4LFN A;  1NN4 A;  4LFN B;  3K7P A;  4LFK B;  3ONO A;  2VVR A;  3QD5 A;  4EM8 A;  2BES A;  4U8E A;  2VVQ A;  4U8F A;  3S5P A;  3HE8 A;  1O1X A;  2VVO A;  5IFZ A;  2VVP A;  3K7S A;  3PH4 A;  3PH3 A;  2PPW A;  3M1P A;  4LFM A;  4LFK A;  4LFL A;  3C5Y A;  3SDW A;  4LFM B;  3SGW A;  3HEE A;  3K8C A;  4LFL B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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