3K8CA

Complex of trypanosoma cruzi ribose 5-phosphate isomerase type b with 4-deoxy-4-phospho-d-erythronohydroxamic acid
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
152
structure length
152
Chain Sequence
MTRRVAIGTDHPAFAIHENLILYVKEAGDEFVPVYCGPKTAESVDYPDFASRVAEMVARKEVEFGVLACGSGIGMSIAANKVPGVRAALCHDHYTAAMSRIHNDANIVCVGERTTGVEVIREIIITFLQTPFSGEERHVRRIEKIRAIEASH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
molecule keywords Ribose 5-phosphate isomerase
publication title Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family.
pubmed doi rcsb
source organism Trypanosoma cruzi
total genus 56
structure length 152
sequence length 152
chains with identical sequence B
ec nomenclature ec 5.3.1.6: Ribose-5-phosphate isomerase.
pdb deposition date 2009-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02502 LacAB_rpiB Ribose/Galactose Isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1400.10 Alpha Beta 3-Layer(aba) Sandwich Ribose 5-phosphate Isomerase B; Chain: A, Sugar-phosphate isomerase, RpiB/LacA/LacB 3k8cA00
4U8FA 4LFKB 4LFNB 3K7PA 3PH4A 3M1PA 3K7OA 3K8CA 4EM8A 3K7SA 5IFZA 2VVRA 4LFKA 3HEEA 2VVPA 4LFNA 3QD5A 3PH3A 2BESA 3SDWA 4LFMB 4LFLB 2VVOA 3SGWA 1NN4A 2VVQA 2BETA 3ONOA 2PPWA 3HE8A 1USLA 4LFMA 3C5YA 4U8EA 4LFLA 1O1XA 3S5PA
chains in the Genus database with same CATH superfamily
4U8FA 4LFKB 4LFNB 3K7PA 3PH4A 3M1PA 3K7OA 3K8CA 4EM8A 3K7SA 5IFZA 2VVRA 4LFKA 3HEEA 2VVPA 4LFNA 3QD5A 3PH3A 2BESA 3SDWA 4LFMB 4LFLB 2VVOA 3SGWA 1NN4A 2VVQA 2BETA 3ONOA 2PPWA 3HE8A 1USLA 4LFMA 3C5YA 4U8EA 4LFLA 1O1XA 3S5PA
chains in the Genus database with same CATH topology
4U8FA 4LFKB 4LFNB 3K7PA 3PH4A 3M1PA 3K7OA 3K8CA 4EM8A 3K7SA 5IFZA 2VVRA 4LFKA 3HEEA 2VVPA 4LFNA 3QD5A 3PH3A 2BESA 3SDWA 4LFMB 4LFLB 2VVOA 3SGWA 1NN4A 2VVQA 2BETA 3ONOA 2PPWA 3HE8A 1USLA 4LFMA 3C5YA 4U8EA 4LFLA 1O1XA 3S5PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U8F A;  4LFK B;  4LFN B;  3K7P A;  3PH4 A;  3M1P A;  3K7O A;  3K8C A;  4EM8 A;  3K7S A;  5IFZ A;  2VVR A;  4LFK A;  3HEE A;  2VVP A;  4LFN A;  3QD5 A;  3PH3 A;  2BES A;  3SDW A;  4LFM B;  4LFL B;  2VVO A;  3SGW A;  1NN4 A;  2VVQ A;  2BET A;  3ONO A;  2PPW A;  3HE8 A;  1USL A;  4LFM A;  3C5Y A;  4U8E A;  4LFL A;  1O1X A;  3S5P A; 
#chains in the Genus database with same CATH topology
 4U8F A;  4LFK B;  4LFN B;  3K7P A;  3PH4 A;  3M1P A;  3K7O A;  3K8C A;  4EM8 A;  3K7S A;  5IFZ A;  2VVR A;  4LFK A;  3HEE A;  2VVP A;  4LFN A;  3QD5 A;  3PH3 A;  2BES A;  3SDW A;  4LFM B;  4LFL B;  2VVO A;  3SGW A;  1NN4 A;  2VVQ A;  2BET A;  3ONO A;  2PPW A;  3HE8 A;  1USL A;  4LFM A;  3C5Y A;  4U8E A;  4LFL A;  1O1X A;  3S5P A; 
#chains in the Genus database with same CATH homology
 4U8F A;  4LFK B;  4LFN B;  3K7P A;  3PH4 A;  3M1P A;  3K7O A;  3K8C A;  4EM8 A;  3K7S A;  5IFZ A;  2VVR A;  4LFK A;  3HEE A;  2VVP A;  4LFN A;  3QD5 A;  3PH3 A;  2BES A;  3SDW A;  4LFM B;  4LFL B;  2VVO A;  3SGW A;  1NN4 A;  2VVQ A;  2BET A;  3ONO A;  2PPW A;  3HE8 A;  1USL A;  4LFM A;  3C5Y A;  4U8E A;  4LFL A;  1O1X A;  3S5P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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