2EE4A

Solution structure of the rhogap domain from human rho gtpase activating protein 5 variant
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
209
structure length
209
Chain Sequence
GSSGSSGWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant
rcsb
molecule keywords Rho GTPase activating protein 5 variant
molecule tags Hydrolase
source organism Homo sapiens
total genus 45
structure length 209
sequence length 209
ec nomenclature ec 3.6.5.2: Small monomeric GTPase.
pdb deposition date 2007-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 2ee4A01
1F7CA 5C2JA 2EE4A 1GRNB 2OVJA 3WPSA 3MSXB 3WPQA 3KUQA 1PBWA 5JCPA 2EE5A 2NGRB 1OW3A 3QISA 2MBGA 5IRCA 1XA6A 1AM4A 3W6RA 2OSAA 5HPYA 5C5SA 5JD0A 1RGPA 3FK2A 3BYIA 1TX4A 3EAPA 2QV2A 3IUGA 3CXLA 2XS6A
chains in the Genus database with same CATH superfamily
1F7CA 5C2JA 2EE4A 1GRNB 2OVJA 3WPSA 3MSXB 3WPQA 3KUQA 1PBWA 5JCPA 2EE5A 2NGRB 1OW3A 3QISA 2MBGA 5IRCA 1XA6A 1AM4A 3W6RA 2OSAA 5HPYA 5C5SA 5JD0A 1RGPA 3FK2A 3BYIA 1TX4A 3EAPA 2QV2A 3IUGA 3CXLA 2XS6A
chains in the Genus database with same CATH topology
1F7CA 5C2JA 2EE4A 1GRNB 2OVJA 3WPSA 3MSXB 3WPQA 3KUQA 1PBWA 5JCPA 2EE5A 2NGRB 1OW3A 3QISA 2MBGA 5IRCA 1XA6A 1AM4A 3W6RA 2OSAA 5HPYA 5C5SA 5JD0A 1RGPA 3FK2A 3BYIA 1TX4A 3EAPA 2QV2A 3IUGA 3CXLA 2XS6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F7C A;  5C2J A;  2EE4 A;  1GRN B;  2OVJ A;  3WPS A;  3MSX B;  3WPQ A;  3KUQ A;  1PBW A;  5JCP A;  2EE5 A;  2NGR B;  1OW3 A;  3QIS A;  2MBG A;  5IRC A;  1XA6 A;  1AM4 A;  3W6R A;  2OSA A;  5HPY A;  5C5S A;  5JD0 A;  1RGP A;  3FK2 A;  3BYI A;  1TX4 A;  3EAP A;  2QV2 A;  3IUG A;  3CXL A;  2XS6 A; 
#chains in the Genus database with same CATH topology
 1F7C A;  5C2J A;  2EE4 A;  1GRN B;  2OVJ A;  3WPS A;  3MSX B;  3WPQ A;  3KUQ A;  1PBW A;  5JCP A;  2EE5 A;  2NGR B;  1OW3 A;  3QIS A;  2MBG A;  5IRC A;  1XA6 A;  1AM4 A;  3W6R A;  2OSA A;  5HPY A;  5C5S A;  5JD0 A;  1RGP A;  3FK2 A;  3BYI A;  1TX4 A;  3EAP A;  2QV2 A;  3IUG A;  3CXL A;  2XS6 A; 
#chains in the Genus database with same CATH homology
 1F7C A;  5C2J A;  2EE4 A;  1GRN B;  2OVJ A;  3WPS A;  3MSX B;  3WPQ A;  3KUQ A;  1PBW A;  5JCP A;  2EE5 A;  2NGR B;  1OW3 A;  3QIS A;  2MBG A;  5IRC A;  1XA6 A;  1AM4 A;  3W6R A;  2OSA A;  5HPY A;  5C5S A;  5JD0 A;  1RGP A;  3FK2 A;  3BYI A;  1TX4 A;  3EAP A;  2QV2 A;  3IUG A;  3CXL A;  2XS6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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