2EE5A

Solution structure of the n-teruminus extended rhogap domain from human rho gtpase activating protein 5 variant
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
219
structure length
219
Chain Sequence
GSSGSSGKNFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the N-teruminus extended RhoGAP domain from human Rho GTPase activating protein 5 variant
rcsb
molecule keywords Rho GTPase activating protein 5 variant
molecule tags Hydrolase
source organism Homo sapiens
total genus 46
structure length 219
sequence length 219
ec nomenclature ec 3.6.5.2: Small monomeric GTPase.
pdb deposition date 2007-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 2ee5A01
5C5SA 5C2JA 3FK2A 3KUQA 1PBWA 3WPQA 1XA6A 3CXLA 3EAPA 5JD0A 3IUGA 2NGRB 3BYIA 2EE4A 1F7CA 1AM4A 2OSAA 2QV2A 2MBGA 1GRNB 1RGPA 3WPSA 2EE5A 3MSXB 2OVJA 3W6RA 2XS6A 5JCPA 5IRCA 1TX4A 1OW3A 5HPYA 3QISA
chains in the Genus database with same CATH superfamily
5C5SA 5C2JA 3FK2A 3KUQA 1PBWA 3WPQA 1XA6A 3CXLA 3EAPA 5JD0A 3IUGA 2NGRB 3BYIA 2EE4A 1F7CA 1AM4A 2OSAA 2QV2A 2MBGA 1GRNB 1RGPA 3WPSA 2EE5A 3MSXB 2OVJA 3W6RA 2XS6A 5JCPA 5IRCA 1TX4A 1OW3A 5HPYA 3QISA
chains in the Genus database with same CATH topology
5C5SA 5C2JA 3FK2A 3KUQA 1PBWA 3WPQA 1XA6A 3CXLA 3EAPA 5JD0A 3IUGA 2NGRB 3BYIA 2EE4A 1F7CA 1AM4A 2OSAA 2QV2A 2MBGA 1GRNB 1RGPA 3WPSA 2EE5A 3MSXB 2OVJA 3W6RA 2XS6A 5JCPA 5IRCA 1TX4A 1OW3A 5HPYA 3QISA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C5S A;  5C2J A;  3FK2 A;  3KUQ A;  1PBW A;  3WPQ A;  1XA6 A;  3CXL A;  3EAP A;  5JD0 A;  3IUG A;  2NGR B;  3BYI A;  2EE4 A;  1F7C A;  1AM4 A;  2OSA A;  2QV2 A;  2MBG A;  1GRN B;  1RGP A;  3WPS A;  2EE5 A;  3MSX B;  2OVJ A;  3W6R A;  2XS6 A;  5JCP A;  5IRC A;  1TX4 A;  1OW3 A;  5HPY A;  3QIS A; 
#chains in the Genus database with same CATH topology
 5C5S A;  5C2J A;  3FK2 A;  3KUQ A;  1PBW A;  3WPQ A;  1XA6 A;  3CXL A;  3EAP A;  5JD0 A;  3IUG A;  2NGR B;  3BYI A;  2EE4 A;  1F7C A;  1AM4 A;  2OSA A;  2QV2 A;  2MBG A;  1GRN B;  1RGP A;  3WPS A;  2EE5 A;  3MSX B;  2OVJ A;  3W6R A;  2XS6 A;  5JCP A;  5IRC A;  1TX4 A;  1OW3 A;  5HPY A;  3QIS A; 
#chains in the Genus database with same CATH homology
 5C5S A;  5C2J A;  3FK2 A;  3KUQ A;  1PBW A;  3WPQ A;  1XA6 A;  3CXL A;  3EAP A;  5JD0 A;  3IUG A;  2NGR B;  3BYI A;  2EE4 A;  1F7C A;  1AM4 A;  2OSA A;  2QV2 A;  2MBG A;  1GRN B;  1RGP A;  3WPS A;  2EE5 A;  3MSX B;  2OVJ A;  3W6R A;  2XS6 A;  5JCP A;  5IRC A;  1TX4 A;  1OW3 A;  5HPY A;  3QIS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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