2H2PA

Crystal structure of clc-ec1 in complex with fab fragment in secn-
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
444
structure length
444
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Uncoupling of a CLC Cl(-)/H(+) Exchange Transporter by Polyatomic Anions
pubmed doi rcsb
molecule tags Ion transport
source organism Escherichia coli
molecule keywords CLC Cl transporter
total genus 166
structure length 444
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 2h2pA00
2HTKA 2EZ0A 2HT4A 1KPKA 4KKBA 4FTPA 1OTUA 3DETA 2EXYA 2FECA 4LOUA 5HD8A 4KK6A 4FG6A 2FEDA 4KJPA 4KKLA 1OTTA 1OTSA 2FEEA 2R9HA 4KJQA 4ENEA 3ORGA 4KJWA 2EXWA 2HT3A 3NMOA 2HLFA 1KPLA 3ND0A 2HT2A 4KK8A 4MQXA 2H2SA 3EJZA 3EJYA 4KKCA 4KK9A 4KK5A 2HTLA 2H2PA 4KKAA 3Q17A
chains in the Genus database with same CATH superfamily
2HTKA 2EZ0A 2HT4A 1KPKA 4KKBA 4FTPA 1OTUA 3DETA 2EXYA 2FECA 4LOUA 5HD8A 4KK6A 4FG6A 2FEDA 4KJPA 4KKLA 1OTTA 1OTSA 2FEEA 2R9HA 4KJQA 4ENEA 3ORGA 4KJWA 2EXWA 2HT3A 3NMOA 2HLFA 1KPLA 3ND0A 2HT2A 4KK8A 4MQXA 2H2SA 3EJZA 3EJYA 4KKCA 4KK9A 4KK5A 2HTLA 2H2PA 4KKAA 3Q17A
chains in the Genus database with same CATH topology
2HTKA 2EZ0A 2HT4A 1KPKA 4KKBA 4FTPA 1OTUA 3DETA 2EXYA 2FECA 4LOUA 5HD8A 4KK6A 4FG6A 2FEDA 4KJPA 4KKLA 1OTTA 1OTSA 2FEEA 2R9HA 4KJQA 4ENEA 3ORGA 4KJWA 2EXWA 2HT3A 3NMOA 2HLFA 1KPLA 3ND0A 2HT2A 4KK8A 4MQXA 2H2SA 3EJZA 3EJYA 4KKCA 4KK9A 4KK5A 2HTLA 2H2PA 4KKAA 3Q17A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HTK A;  2EZ0 A;  2HT4 A;  1KPK A;  4KKB A;  4FTP A;  1OTU A;  3DET A;  2EXY A;  2FEC A;  4LOU A;  5HD8 A;  4KK6 A;  4FG6 A;  2FED A;  4KJP A;  4KKL A;  1OTT A;  1OTS A;  2FEE A;  2R9H A;  4KJQ A;  4ENE A;  3ORG A;  4KJW A;  2EXW A;  2HT3 A;  3NMO A;  2HLF A;  1KPL A;  3ND0 A;  2HT2 A;  4KK8 A;  4MQX A;  2H2S A;  3EJZ A;  3EJY A;  4KKC A;  4KK9 A;  4KK5 A;  2HTL A;  2H2P A;  4KKA A;  3Q17 A; 
#chains in the Genus database with same CATH topology
 2HTK A;  2EZ0 A;  2HT4 A;  1KPK A;  4KKB A;  4FTP A;  1OTU A;  3DET A;  2EXY A;  2FEC A;  4LOU A;  5HD8 A;  4KK6 A;  4FG6 A;  2FED A;  4KJP A;  4KKL A;  1OTT A;  1OTS A;  2FEE A;  2R9H A;  4KJQ A;  4ENE A;  3ORG A;  4KJW A;  2EXW A;  2HT3 A;  3NMO A;  2HLF A;  1KPL A;  3ND0 A;  2HT2 A;  4KK8 A;  4MQX A;  2H2S A;  3EJZ A;  3EJY A;  4KKC A;  4KK9 A;  4KK5 A;  2HTL A;  2H2P A;  4KKA A;  3Q17 A; 
#chains in the Genus database with same CATH homology
 2HTK A;  2EZ0 A;  2HT4 A;  1KPK A;  4KKB A;  4FTP A;  1OTU A;  3DET A;  2EXY A;  2FEC A;  4LOU A;  5HD8 A;  4KK6 A;  4FG6 A;  2FED A;  4KJP A;  4KKL A;  1OTT A;  1OTS A;  2FEE A;  2R9H A;  4KJQ A;  4ENE A;  3ORG A;  4KJW A;  2EXW A;  2HT3 A;  3NMO A;  2HLF A;  1KPL A;  3ND0 A;  2HT2 A;  4KK8 A;  4MQX A;  2H2S A;  3EJZ A;  3EJY A;  4KKC A;  4KK9 A;  4KK5 A;  2HTL A;  2H2P A;  4KKA A;  3Q17 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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