2H2P | Genus

Total Genus 166

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	166
sequence length	444
structure length	444
Chain Sequence	RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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Time for openFile(/file/5cfd1e658199e9cd72c2acec/pdb.gz): 1756 ms

reading 444 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

444 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 40 ms

Adding embedded #jmolscript: select ({0:443});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Ion transport
source organism	Escherichia coli
publication title	Uncoupling of a CLC Cl(-)/H(+) Exchange Transporter by Polyatomic Anions pubmed doi rcsb
molecule keywords	CLC Cl transporter
total genus	166
structure length	444
sequence length	444
chains with identical sequence	B
ec nomenclature
pdb deposition date	2006-05-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00654	Voltage_CLC	Voltage gated chloride channel

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.3080.10	Mainly Alpha	Orthogonal Bundle	Clc chloride channel	Clc chloride channel	2h2pA00

2EXWA 4KKBA 3EJYA 2HTLA 4LOUA 4KJQA 4FG6A 1OTUA 4MQXA 2H2PA 2R9HA 2HT4A 4KKLA 1KPKA 5HD8A 4KKCA 4KJPA 3EJZA 4KJWA 2FECA 2HTKA 3NMOA 3ORGA 4ENEA 2EZ0A 2EXYA 2FEDA 4KK8A 2HLFA 4KK9A 1KPLA 1OTSA 4KK5A 3Q17A 2H2SA 3ND0A 4KKAA 2HT2A 4KK6A 1OTTA 2HT3A 2FEEA 4FTPA 3DETA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2EXW A;  4KKB A;  3EJY A;  2HTL A;  4LOU A;  4KJQ A;  4FG6 A;  1OTU A;  4MQX A;  2H2P A;  2R9H A;  2HT4 A;  4KKL A;  1KPK A;  5HD8 A;  4KKC A;  4KJP A;  3EJZ A;  4KJW A;  2FEC A;  2HTK A;  3NMO A;  3ORG A;  4ENE A;  2EZ0 A;  2EXY A;  2FED A;  4KK8 A;  2HLF A;  4KK9 A;  1KPL A;  1OTS A;  4KK5 A;  3Q17 A;  2H2S A;  3ND0 A;  4KKA A;  2HT2 A;  4KK6 A;  1OTT A;  2HT3 A;  2FEE A;  4FTP A;  3DET A; 
#chains in the Genus database with same CATH topology
 2EXW A;  4KKB A;  3EJY A;  2HTL A;  4LOU A;  4KJQ A;  4FG6 A;  1OTU A;  4MQX A;  2H2P A;  2R9H A;  2HT4 A;  4KKL A;  1KPK A;  5HD8 A;  4KKC A;  4KJP A;  3EJZ A;  4KJW A;  2FEC A;  2HTK A;  3NMO A;  3ORG A;  4ENE A;  2EZ0 A;  2EXY A;  2FED A;  4KK8 A;  2HLF A;  4KK9 A;  1KPL A;  1OTS A;  4KK5 A;  3Q17 A;  2H2S A;  3ND0 A;  4KKA A;  2HT2 A;  4KK6 A;  1OTT A;  2HT3 A;  2FEE A;  4FTP A;  3DET A; 
#chains in the Genus database with same CATH homology
 2EXW A;  4KKB A;  3EJY A;  2HTL A;  4LOU A;  4KJQ A;  4FG6 A;  1OTU A;  4MQX A;  2H2P A;  2R9H A;  2HT4 A;  4KKL A;  1KPK A;  5HD8 A;  4KKC A;  4KJP A;  3EJZ A;  4KJW A;  2FEC A;  2HTK A;  3NMO A;  3ORG A;  4ENE A;  2EZ0 A;  2EXY A;  2FED A;  4KK8 A;  2HLF A;  4KK9 A;  1KPL A;  1OTS A;  4KK5 A;  3Q17 A;  2H2S A;  3ND0 A;  4KKA A;  2HT2 A;  4KK6 A;  1OTT A;  2HT3 A;  2FEE A;  4FTP A;  3DET A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2H2PA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations