2IN8 | Genus

Total Genus 30

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	30
sequence length	139
structure length	139
Chain Sequence	CLAEGTRIFDPVTGTTHRIEDVVGGRKPIHVVAAAKDGTLHARPVVSWFDQGTRDVIGLRIAGGAILWATPDHKVLTEYGWRAAGELRKGDRVAVRDVETGELRYSVIREVLPTRRARTFGLEVEELHTLVAEGVVVHN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 139 atoms

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139 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Mycobacterium tuberculosis
publication title	Crystallographic and mutational studies of Mycobacterium tuberculosis recA mini-inteins suggest a pivotal role for a highly conserved aspartate residue. pubmed doi rcsb
molecule keywords	Endonuclease PI-MtuI
total genus	30
structure length	139
sequence length	139
ec nomenclature	ec 3.1.-.-:
pdb deposition date	2006-10-06

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF14890	Intein_splicing	Intein splicing domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.170.16.10	Mainly Beta	Beta Complex	Endonuclease - Pi-scei; Chain A, domain 1	Hedgehog/Intein (Hint) domain	2in8A00

4OZ6A 1AT0A 1ZD7A 4E2TA 3IFJA 2IN8A 5I0AA 1UM2A 4E2UA 2JMZA 2IN9A 1LWTA 2IN0A 1VDEA 3NZMA 2JNQA 2L8LA 2KEQA 3IGDA 4GIGA 1ZDEA 4KL6A 1DFAA 1MI8A 4O1SA 2LCJA 1DQ3A 2CW8A 2CW7A 1LWSA 1JVAA 4KL5A 1AM2A 2IMZA 1GPPA 2LWYA 4O1RA 5K08A 2LQMA 1EF0A
chains in the Genus database with same CATH superfamily

4OZ6A 1AT0A 1ZD7A 4LX3A 4E2TA 3IFJA 2IN8A 5I0AA 1UM2A 4E2UA 2JMZA 2IN9A 1LWTA 2IN0A 1VDEA 3NZMA 2JNQA 2L8LA 2KEQA 3IGDA 4GIGA 1ZDEA 4QFQA 4KL6A 1DFAA 1MI8A 4O1SA 2LCJA 1DQ3A 2CW8A 2CW7A 1LWSA 1JVAA 4KL5A 1AM2A 2IMZA 1GPPA 2LWYA 4O1RA 5K08A 2LQMA 1EF0A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4OZ6 A;  1AT0 A;  1ZD7 A;  4E2T A;  3IFJ A;  2IN8 A;  5I0A A;  1UM2 A;  4E2U A;  2JMZ A;  2IN9 A;  1LWT A;  2IN0 A;  1VDE A;  3NZM A;  2JNQ A;  2L8L A;  2KEQ A;  3IGD A;  4GIG A;  1ZDE A;  4KL6 A;  1DFA A;  1MI8 A;  4O1S A;  2LCJ A;  1DQ3 A;  2CW8 A;  2CW7 A;  1LWS A;  1JVA A;  4KL5 A;  1AM2 A;  2IMZ A;  1GPP A;  2LWY A;  4O1R A;  5K08 A;  2LQM A;  1EF0 A; 
#chains in the Genus database with same CATH topology
 4OZ6 A;  1AT0 A;  1ZD7 A;  4LX3 A;  4E2T A;  3IFJ A;  2IN8 A;  5I0A A;  1UM2 A;  4E2U A;  2JMZ A;  2IN9 A;  1LWT A;  2IN0 A;  1VDE A;  3NZM A;  2JNQ A;  2L8L A;  2KEQ A;  3IGD A;  4GIG A;  1ZDE A;  4QFQ A;  4KL6 A;  1DFA A;  1MI8 A;  4O1S A;  2LCJ A;  1DQ3 A;  2CW8 A;  2CW7 A;  1LWS A;  1JVA A;  4KL5 A;  1AM2 A;  2IMZ A;  1GPP A;  2LWY A;  4O1R A;  5K08 A;  2LQM A;  1EF0 A; 
#chains in the Genus database with same CATH homology
 4OZ6 A;  1AT0 A;  1ZD7 A;  4E2T A;  3IFJ A;  2IN8 A;  5I0A A;  1UM2 A;  4E2U A;  2JMZ A;  2IN9 A;  1LWT A;  2IN0 A;  1VDE A;  3NZM A;  2JNQ A;  2L8L A;  2KEQ A;  3IGD A;  4GIG A;  1ZDE A;  4KL6 A;  1DFA A;  1MI8 A;  4O1S A;  2LCJ A;  1DQ3 A;  2CW8 A;  2CW7 A;  1LWS A;  1JVA A;  4KL5 A;  1AM2 A;  2IMZ A;  1GPP A;  2LWY A;  4O1R A;  5K08 A;  2LQM A;  1EF0 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2IN8A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations