2LQMA

Solution structures of rada intein from pyrococcus horikoshii
Total Genus 37
2040608010012014016005101520253035
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
174
structure length
174
Chain Sequence
AFARDTEVYYENDTVPHMESIEEMYSKYASMNGELPFDNGYAVPLDNVFVYTLDIASGEIKKTRASYIYREKVEKLIEIKLSSGYSLKVTPSHPVLLFRDGLQWVPAAEVKPGDVVVGVREEVLRRRIISKGELEFHEVSSVRIIDYNNWVYDLVIPETHNFIAPNGLVLHNAQ

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
S1 (2-3)S13 (135-155)TI1 (3-6)S9 (86-89)S2 (7-12)TI7 (164-167)S6 (48-54)S7 (59-64)TIV3 (45-48)AH1 (21-32)S5 (40-44)S4 (35-36)TI2 (37-40)EMPTYTIV6 (156-159)TIV4 (54-57)TI3 (55-58)S8 (67-81)TI4 (81-84)TI5 (90-93)S10 (94-98)S15 (169-171)TIV5 (98-101)S12 (114-118)S11 (102-106)3H1 (107-109)TII1 (111-114)TI6 (120-123)3H2 (123-125)TVIII1 (126-129)O1 (129-131)TIV7 (157-160)S14 (161-163)S3 (15-20)Updating...
connected with : NaN
molecule tags Unknown function
source organism Pyrococcus horikoshii
publication title NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein.
pubmed doi rcsb
molecule keywords Pho radA intein
total genus 37
structure length 174
sequence length 174
ec nomenclature
pdb deposition date 2012-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14890 Intein_splicing Intein splicing domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.16.10 Mainly Beta Beta Complex Endonuclease - Pi-scei; Chain A, domain 1 Hedgehog/Intein (Hint) domain 2lqmA00
2L8LA 1ZD7A 1LWTA 2JNQA 1UM2A 4KL5A 2IN8A 2LQMA 2CW7A 2CW8A 2JMZA 4GIGA 1EF0A 2IN9A 4OZ6A 1JVAA 1DFAA 2IMZA 5I0AA 1LWSA 4O1SA 1VDEA 1AT0A 4O1RA 4E2UA 2LCJA 1DQ3A 3IGDA 4E2TA 5K08A 3IFJA 4KL6A 1ZDEA 2IN0A 2LWYA 3NZMA 1AM2A 1GPPA 1MI8A 2KEQA
chains in the Genus database with same CATH superfamily
2L8LA 4LX3A 1ZD7A 1LWTA 2JNQA 1UM2A 4KL5A 2IN8A 2LQMA 2CW7A 2CW8A 2JMZA 4GIGA 1EF0A 2IN9A 4OZ6A 1JVAA 1DFAA 2IMZA 5I0AA 1LWSA 4O1SA 1VDEA 1AT0A 4O1RA 4E2UA 4QFQA 2LCJA 1DQ3A 3IGDA 4E2TA 5K08A 3IFJA 4KL6A 1ZDEA 2IN0A 2LWYA 3NZMA 1AM2A 1GPPA 1MI8A 2KEQA
chains in the Genus database with same CATH topology
2L8LA 1ZD7A 1LWTA 2JNQA 1UM2A 4KL5A 2IN8A 2LQMA 2CW7A 2CW8A 2JMZA 4GIGA 1EF0A 2IN9A 4OZ6A 1JVAA 1DFAA 2IMZA 5I0AA 1LWSA 4O1SA 1VDEA 1AT0A 4O1RA 4E2UA 2LCJA 1DQ3A 3IGDA 4E2TA 5K08A 3IFJA 4KL6A 1ZDEA 2IN0A 2LWYA 3NZMA 1AM2A 1GPPA 1MI8A 2KEQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L8L A;  1ZD7 A;  1LWT A;  2JNQ A;  1UM2 A;  4KL5 A;  2IN8 A;  2LQM A;  2CW7 A;  2CW8 A;  2JMZ A;  4GIG A;  1EF0 A;  2IN9 A;  4OZ6 A;  1JVA A;  1DFA A;  2IMZ A;  5I0A A;  1LWS A;  4O1S A;  1VDE A;  1AT0 A;  4O1R A;  4E2U A;  2LCJ A;  1DQ3 A;  3IGD A;  4E2T A;  5K08 A;  3IFJ A;  4KL6 A;  1ZDE A;  2IN0 A;  2LWY A;  3NZM A;  1AM2 A;  1GPP A;  1MI8 A;  2KEQ A; 
#chains in the Genus database with same CATH topology
 2L8L A;  4LX3 A;  1ZD7 A;  1LWT A;  2JNQ A;  1UM2 A;  4KL5 A;  2IN8 A;  2LQM A;  2CW7 A;  2CW8 A;  2JMZ A;  4GIG A;  1EF0 A;  2IN9 A;  4OZ6 A;  1JVA A;  1DFA A;  2IMZ A;  5I0A A;  1LWS A;  4O1S A;  1VDE A;  1AT0 A;  4O1R A;  4E2U A;  4QFQ A;  2LCJ A;  1DQ3 A;  3IGD A;  4E2T A;  5K08 A;  3IFJ A;  4KL6 A;  1ZDE A;  2IN0 A;  2LWY A;  3NZM A;  1AM2 A;  1GPP A;  1MI8 A;  2KEQ A; 
#chains in the Genus database with same CATH homology
 2L8L A;  1ZD7 A;  1LWT A;  2JNQ A;  1UM2 A;  4KL5 A;  2IN8 A;  2LQM A;  2CW7 A;  2CW8 A;  2JMZ A;  4GIG A;  1EF0 A;  2IN9 A;  4OZ6 A;  1JVA A;  1DFA A;  2IMZ A;  5I0A A;  1LWS A;  4O1S A;  1VDE A;  1AT0 A;  4O1R A;  4E2U A;  2LCJ A;  1DQ3 A;  3IGD A;  4E2T A;  5K08 A;  3IFJ A;  4KL6 A;  1ZDE A;  2IN0 A;  2LWY A;  3NZM A;  1AM2 A;  1GPP A;  1MI8 A;  2KEQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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