2LSRA

Solution structure of harmonin n terminal domain in complex with a exon68 encoded peptide of cadherin23
Total Genus 22
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
80
structure length
80
Chain Sequence
MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFDAIRPLIPLKHQVEYDQLTPR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia
doi rcsb
molecule tags Structural protein/cell adhesion
source organism Homo sapiens
molecule keywords Harmonin
total genus 22
structure length 80
sequence length 80
ec nomenclature
pdb deposition date 2012-05-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 2lsrA00
2LSRA 4YL6A 4Y5OA 4YKCA 4YKDA 5F3XA 4FQNA 2KBRA 2KBQA 3K1RA
chains in the Genus database with same CATH superfamily
2RMRA 1E91A 4YL6A 2RMSA 5F3XA 4FQNA 2L9SB 3K1RA 4YKCA 1G1EB 1S5QB 2KBRA 2LD7B 2F05A 1S5RB 2LSRA 1PD7A 4Y5OA 4YKDA 2CZYA 2CR7A 2KBQA
chains in the Genus database with same CATH topology
2LSRA 4YL6A 4Y5OA 4YKCA 4YKDA 5F3XA 4FQNA 2KBRA 2KBQA 3K1RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LSR A;  4YL6 A;  4Y5O A;  4YKC A;  4YKD A;  5F3X A;  4FQN A;  2KBR A;  2KBQ A;  3K1R A; 
#chains in the Genus database with same CATH topology
 2RMR A;  1E91 A;  4YL6 A;  2RMS A;  5F3X A;  4FQN A;  2L9S B;  3K1R A;  4YKC A;  1G1E B;  1S5Q B;  2KBR A;  2LD7 B;  2F05 A;  1S5R B;  2LSR A;  1PD7 A;  4Y5O A;  4YKD A;  2CZY A;  2CR7 A;  2KBQ A; 
#chains in the Genus database with same CATH homology
 2LSR A;  4YL6 A;  4Y5O A;  4YKC A;  4YKD A;  5F3X A;  4FQN A;  2KBR A;  2KBQ A;  3K1R A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...