2NGR | Genus

Total Genus 71

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	71
sequence length	196
structure length	196
Chain Sequence	LPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFARSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFP

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 196 atoms

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196 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP. pubmed doi rcsb
molecule keywords	PROTEIN (GTP BINDING PROTEIN (G25K))
molecule tags	Hydrolase
source organism	Homo sapiens
total genus	71
structure length	196
sequence length	196
ec nomenclature
pdb deposition date	1998-07-31

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF00620	RhoGAP	RhoGAP domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.555.10	Mainly Alpha	Orthogonal Bundle	Phosphatidylinositol 3-kinase; Chain A	Rho GTPase activation protein	2ngrB00

5IRCA 3BYIA 3FK2A 1OW3A 1XA6A 2QV2A 5HPYA 2OSAA 1AM4A 3WPSA 3IUGA 1GRNB 3WPQA 2OVJA 1RGPA 3EAPA 2XS6A 5C5SA 1F7CA 1PBWA 3QISA 3W6RA 3MSXB 3CXLA 5JD0A 2NGRB 2EE5A 2EE4A 5C2JA 2MBGA 5JCPA 1TX4A 3KUQA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5IRC A;  3BYI A;  3FK2 A;  1OW3 A;  1XA6 A;  2QV2 A;  5HPY A;  2OSA A;  1AM4 A;  3WPS A;  3IUG A;  1GRN B;  3WPQ A;  2OVJ A;  1RGP A;  3EAP A;  2XS6 A;  5C5S A;  1F7C A;  1PBW A;  3QIS A;  3W6R A;  3MSX B;  3CXL A;  5JD0 A;  2NGR B;  2EE5 A;  2EE4 A;  5C2J A;  2MBG A;  5JCP A;  1TX4 A;  3KUQ A; 
#chains in the Genus database with same CATH topology
 5IRC A;  3BYI A;  3FK2 A;  1OW3 A;  1XA6 A;  2QV2 A;  5HPY A;  2OSA A;  1AM4 A;  3WPS A;  3IUG A;  1GRN B;  3WPQ A;  2OVJ A;  1RGP A;  3EAP A;  2XS6 A;  5C5S A;  1F7C A;  1PBW A;  3QIS A;  3W6R A;  3MSX B;  3CXL A;  5JD0 A;  2NGR B;  2EE5 A;  2EE4 A;  5C2J A;  2MBG A;  5JCP A;  1TX4 A;  3KUQ A; 
#chains in the Genus database with same CATH homology
 5IRC A;  3BYI A;  3FK2 A;  1OW3 A;  1XA6 A;  2QV2 A;  5HPY A;  2OSA A;  1AM4 A;  3WPS A;  3IUG A;  1GRN B;  3WPQ A;  2OVJ A;  1RGP A;  3EAP A;  2XS6 A;  5C5S A;  1F7C A;  1PBW A;  3QIS A;  3W6R A;  3MSX B;  3CXL A;  5JD0 A;  2NGR B;  2EE5 A;  2EE4 A;  5C2J A;  2MBG A;  5JCP A;  1TX4 A;  3KUQ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2NGRB

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations