2OSAA

The rho-gap domain of human n-chimaerin
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
196
structure length
196
Chain Sequence
KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the Rho-GAP domain from human N-chimaerin
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords N-chimaerin
total genus 75
structure length 196
sequence length 196
ec nomenclature
pdb deposition date 2007-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 2osaA00
1AM4A 1OW3A 1TX4A 3BYIA 5C2JA 3WPSA 3EAPA 3MSXB 5HPYA 2OVJA 5JD0A 1GRNB 5JCPA 2EE5A 5IRCA 3W6RA 1XA6A 2OSAA 3WPQA 3IUGA 3QISA 1RGPA 1F7CA 3KUQA 5C5SA 2NGRB 1PBWA 2MBGA 3CXLA 2EE4A 2QV2A 3FK2A 2XS6A
chains in the Genus database with same CATH superfamily
1AM4A 1OW3A 1TX4A 3BYIA 5C2JA 3WPSA 3EAPA 3MSXB 5HPYA 2OVJA 5JD0A 1GRNB 5JCPA 2EE5A 5IRCA 3W6RA 1XA6A 2OSAA 3WPQA 3IUGA 3QISA 1RGPA 1F7CA 3KUQA 5C5SA 2NGRB 1PBWA 2MBGA 3CXLA 2EE4A 2QV2A 3FK2A 2XS6A
chains in the Genus database with same CATH topology
1AM4A 1OW3A 1TX4A 3BYIA 5C2JA 3WPSA 3EAPA 3MSXB 5HPYA 2OVJA 5JD0A 1GRNB 5JCPA 2EE5A 5IRCA 3W6RA 1XA6A 2OSAA 3WPQA 3IUGA 3QISA 1RGPA 1F7CA 3KUQA 5C5SA 2NGRB 1PBWA 2MBGA 3CXLA 2EE4A 2QV2A 3FK2A 2XS6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AM4 A;  1OW3 A;  1TX4 A;  3BYI A;  5C2J A;  3WPS A;  3EAP A;  3MSX B;  5HPY A;  2OVJ A;  5JD0 A;  1GRN B;  5JCP A;  2EE5 A;  5IRC A;  3W6R A;  1XA6 A;  2OSA A;  3WPQ A;  3IUG A;  3QIS A;  1RGP A;  1F7C A;  3KUQ A;  5C5S A;  2NGR B;  1PBW A;  2MBG A;  3CXL A;  2EE4 A;  2QV2 A;  3FK2 A;  2XS6 A; 
#chains in the Genus database with same CATH topology
 1AM4 A;  1OW3 A;  1TX4 A;  3BYI A;  5C2J A;  3WPS A;  3EAP A;  3MSX B;  5HPY A;  2OVJ A;  5JD0 A;  1GRN B;  5JCP A;  2EE5 A;  5IRC A;  3W6R A;  1XA6 A;  2OSA A;  3WPQ A;  3IUG A;  3QIS A;  1RGP A;  1F7C A;  3KUQ A;  5C5S A;  2NGR B;  1PBW A;  2MBG A;  3CXL A;  2EE4 A;  2QV2 A;  3FK2 A;  2XS6 A; 
#chains in the Genus database with same CATH homology
 1AM4 A;  1OW3 A;  1TX4 A;  3BYI A;  5C2J A;  3WPS A;  3EAP A;  3MSX B;  5HPY A;  2OVJ A;  5JD0 A;  1GRN B;  5JCP A;  2EE5 A;  5IRC A;  3W6R A;  1XA6 A;  2OSA A;  3WPQ A;  3IUG A;  3QIS A;  1RGP A;  1F7C A;  3KUQ A;  5C5S A;  2NGR B;  1PBW A;  2MBG A;  3CXL A;  2EE4 A;  2QV2 A;  3FK2 A;  2XS6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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