2OSAA

The rho-gap domain of human n-chimaerin
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
196
structure length
196
Chain Sequence
KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the Rho-GAP domain from human N-chimaerin
rcsb
molecule keywords N-chimaerin
molecule tags Signaling protein
source organism Homo sapiens
total genus 75
structure length 196
sequence length 196
ec nomenclature
pdb deposition date 2007-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 2osaA00
3FK2A 3W6RA 1OW3A 3CXLA 5JD0A 2XS6A 2OVJA 5HPYA 1GRNB 2OSAA 1F7CA 5IRCA 3IUGA 1AM4A 3MSXB 1RGPA 1TX4A 1PBWA 3EAPA 3KUQA 3BYIA 5C2JA 5JCPA 2NGRB 3WPQA 5C5SA 1XA6A 2MBGA 2EE5A 3QISA 3WPSA 2QV2A 2EE4A
chains in the Genus database with same CATH superfamily
3FK2A 3W6RA 1OW3A 3CXLA 5JD0A 2XS6A 2OVJA 5HPYA 1GRNB 2OSAA 1F7CA 5IRCA 3IUGA 1AM4A 3MSXB 1RGPA 1TX4A 1PBWA 3EAPA 3KUQA 3BYIA 5C2JA 5JCPA 2NGRB 3WPQA 5C5SA 1XA6A 2MBGA 2EE5A 3QISA 3WPSA 2QV2A 2EE4A
chains in the Genus database with same CATH topology
3FK2A 3W6RA 1OW3A 3CXLA 5JD0A 2XS6A 2OVJA 5HPYA 1GRNB 2OSAA 1F7CA 5IRCA 3IUGA 1AM4A 3MSXB 1RGPA 1TX4A 1PBWA 3EAPA 3KUQA 3BYIA 5C2JA 5JCPA 2NGRB 3WPQA 5C5SA 1XA6A 2MBGA 2EE5A 3QISA 3WPSA 2QV2A 2EE4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FK2 A;  3W6R A;  1OW3 A;  3CXL A;  5JD0 A;  2XS6 A;  2OVJ A;  5HPY A;  1GRN B;  2OSA A;  1F7C A;  5IRC A;  3IUG A;  1AM4 A;  3MSX B;  1RGP A;  1TX4 A;  1PBW A;  3EAP A;  3KUQ A;  3BYI A;  5C2J A;  5JCP A;  2NGR B;  3WPQ A;  5C5S A;  1XA6 A;  2MBG A;  2EE5 A;  3QIS A;  3WPS A;  2QV2 A;  2EE4 A; 
#chains in the Genus database with same CATH topology
 3FK2 A;  3W6R A;  1OW3 A;  3CXL A;  5JD0 A;  2XS6 A;  2OVJ A;  5HPY A;  1GRN B;  2OSA A;  1F7C A;  5IRC A;  3IUG A;  1AM4 A;  3MSX B;  1RGP A;  1TX4 A;  1PBW A;  3EAP A;  3KUQ A;  3BYI A;  5C2J A;  5JCP A;  2NGR B;  3WPQ A;  5C5S A;  1XA6 A;  2MBG A;  2EE5 A;  3QIS A;  3WPS A;  2QV2 A;  2EE4 A; 
#chains in the Genus database with same CATH homology
 3FK2 A;  3W6R A;  1OW3 A;  3CXL A;  5JD0 A;  2XS6 A;  2OVJ A;  5HPY A;  1GRN B;  2OSA A;  1F7C A;  5IRC A;  3IUG A;  1AM4 A;  3MSX B;  1RGP A;  1TX4 A;  1PBW A;  3EAP A;  3KUQ A;  3BYI A;  5C2J A;  5JCP A;  2NGR B;  3WPQ A;  5C5S A;  1XA6 A;  2MBG A;  2EE5 A;  3QIS A;  3WPS A;  2QV2 A;  2EE4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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