2R9HA

Crystal structure of q207c mutant of clc-ec1 in complex with fab
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
444
structure length
444
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPCFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Q207C Mutant of CLC-ec1 in complex with Fab
rcsb
molecule tags Membrane protein
source organism Escherichia coli
molecule keywords H(+)/Cl(-) exchange transporter clcA
total genus 170
structure length 444
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 2r9hA00
4KKAA 4KK5A 4KJPA 2H2SA 1KPKA 4KKBA 2HT2A 4ENEA 2FEDA 4KKCA 3Q17A 4FTPA 4KK8A 4LOUA 3NMOA 3EJYA 1KPLA 1OTUA 2H2PA 4FG6A 2HLFA 4KJQA 2EXWA 3ND0A 1OTTA 2EXYA 4KK6A 4KJWA 4KK9A 2HT4A 4MQXA 2HTKA 5HD8A 3EJZA 2HT3A 2HTLA 1OTSA 3ORGA 2FECA 2R9HA 4KKLA 3DETA 2EZ0A 2FEEA
chains in the Genus database with same CATH superfamily
4KKAA 4KK5A 4KJPA 2H2SA 1KPKA 4KKBA 2HT2A 4ENEA 2FEDA 4KKCA 3Q17A 4FTPA 4KK8A 4LOUA 3NMOA 3EJYA 1KPLA 1OTUA 2H2PA 4FG6A 2HLFA 4KJQA 2EXWA 3ND0A 1OTTA 2EXYA 4KK6A 4KJWA 4KK9A 2HT4A 4MQXA 2HTKA 5HD8A 3EJZA 2HT3A 2HTLA 1OTSA 3ORGA 2FECA 2R9HA 4KKLA 3DETA 2EZ0A 2FEEA
chains in the Genus database with same CATH topology
4KKAA 4KK5A 4KJPA 2H2SA 1KPKA 4KKBA 2HT2A 4ENEA 2FEDA 4KKCA 3Q17A 4FTPA 4KK8A 4LOUA 3NMOA 3EJYA 1KPLA 1OTUA 2H2PA 4FG6A 2HLFA 4KJQA 2EXWA 3ND0A 1OTTA 2EXYA 4KK6A 4KJWA 4KK9A 2HT4A 4MQXA 2HTKA 5HD8A 3EJZA 2HT3A 2HTLA 1OTSA 3ORGA 2FECA 2R9HA 4KKLA 3DETA 2EZ0A 2FEEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KKA A;  4KK5 A;  4KJP A;  2H2S A;  1KPK A;  4KKB A;  2HT2 A;  4ENE A;  2FED A;  4KKC A;  3Q17 A;  4FTP A;  4KK8 A;  4LOU A;  3NMO A;  3EJY A;  1KPL A;  1OTU A;  2H2P A;  4FG6 A;  2HLF A;  4KJQ A;  2EXW A;  3ND0 A;  1OTT A;  2EXY A;  4KK6 A;  4KJW A;  4KK9 A;  2HT4 A;  4MQX A;  2HTK A;  5HD8 A;  3EJZ A;  2HT3 A;  2HTL A;  1OTS A;  3ORG A;  2FEC A;  2R9H A;  4KKL A;  3DET A;  2EZ0 A;  2FEE A; 
#chains in the Genus database with same CATH topology
 4KKA A;  4KK5 A;  4KJP A;  2H2S A;  1KPK A;  4KKB A;  2HT2 A;  4ENE A;  2FED A;  4KKC A;  3Q17 A;  4FTP A;  4KK8 A;  4LOU A;  3NMO A;  3EJY A;  1KPL A;  1OTU A;  2H2P A;  4FG6 A;  2HLF A;  4KJQ A;  2EXW A;  3ND0 A;  1OTT A;  2EXY A;  4KK6 A;  4KJW A;  4KK9 A;  2HT4 A;  4MQX A;  2HTK A;  5HD8 A;  3EJZ A;  2HT3 A;  2HTL A;  1OTS A;  3ORG A;  2FEC A;  2R9H A;  4KKL A;  3DET A;  2EZ0 A;  2FEE A; 
#chains in the Genus database with same CATH homology
 4KKA A;  4KK5 A;  4KJP A;  2H2S A;  1KPK A;  4KKB A;  2HT2 A;  4ENE A;  2FED A;  4KKC A;  3Q17 A;  4FTP A;  4KK8 A;  4LOU A;  3NMO A;  3EJY A;  1KPL A;  1OTU A;  2H2P A;  4FG6 A;  2HLF A;  4KJQ A;  2EXW A;  3ND0 A;  1OTT A;  2EXY A;  4KK6 A;  4KJW A;  4KK9 A;  2HT4 A;  4MQX A;  2HTK A;  5HD8 A;  3EJZ A;  2HT3 A;  2HTL A;  1OTS A;  3ORG A;  2FEC A;  2R9H A;  4KKL A;  3DET A;  2EZ0 A;  2FEE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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