3CCRK

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
132
structure length
132
Chain Sequence
MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 28
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 3ccrK00
3CCJK 5GAHL 4UY8K 2ZJQH 1Q81L 5AN9E 4WCEH 1S72K 3DLLH 3CCQK 1VQ6K 3CCUK 3CCVK 3PIOH 4V19O 1VQKK 3CD6K 4WF9H 3I55K 1YHQK 5GAGL 3OW2J 1VQMK 4IO9H 2QA4K 3I56K 4U67H 3CCLK 5GADL 1WHIA 1VQ8K 3CC4K 1Q86L 1K8AL 1M1KL 3CCMK 3CXCJ 4WFBH 3CC2K 1QVGJ 1YJ9K 1K9ML 4WFAH 1Q82L 5DM6H 5JVHH 1NJIL 1VQNK 3CPWJ 1VQ5K 1VQOK 5GAEL 3CC7K 3J7YL 3CCSK 3CMAK 3CF5H 3J7ZK 3G6EK 1YI2K 1QVFJ 1KD1L 5HL7H 3CCEK 1JJ2J 2ZJPH 1YIJK 4WFNH 1KQSJ 1YJWK 1VQPK 1W2BJ 3CMEK 5H1SM 4IOCH 1VQLK 3CCRK 1YJNK 2QEXK 3G71K 2OTLK 3G4SK 1K73L 2OTJK 3PIPH 2ZJRH 1M90L 1N8RL 1Q7YL 5MLCM 1VQ9K 5JVGH 1KC8L 1YITK 5DM7H 1VQ4K 4IOAH 1VQ7K
chains in the Genus database with same CATH superfamily
3CCJK 5GAHL 4UY8K 2ZJQH 1Q81L 5AN9E 4WCEH 1S72K 3DLLH 3CCQK 1VQ6K 3CCUK 3CCVK 3PIOH 4V19O 1VQKK 3CD6K 4WF9H 3I55K 1YHQK 5GAGL 3OW2J 1VQMK 4IO9H 2QA4K 3I56K 4U67H 3CCLK 5GADL 1WHIA 1VQ8K 3CC4K 1Q86L 1K8AL 1M1KL 3CCMK 3CXCJ 4WFBH 3CC2K 1QVGJ 1YJ9K 1K9ML 4WFAH 1Q82L 5DM6H 5JVHH 1NJIL 1VQNK 3CPWJ 1VQ5K 1VQOK 5GAEL 3CC7K 3J7YL 3CCSK 3CMAK 3CF5H 3J7ZK 3G6EK 1YI2K 1QVFJ 1KD1L 5HL7H 3CCEK 1JJ2J 2ZJPH 1YIJK 4WFNH 1KQSJ 1YJWK 1VQPK 1W2BJ 3CMEK 5H1SM 4IOCH 1VQLK 3CCRK 1YJNK 2QEXK 3G71K 2OTLK 3G4SK 1K73L 2OTJK 3PIPH 2ZJRH 1M90L 1N8RL 1Q7YL 5MLCM 1VQ9K 5JVGH 1KC8L 1YITK 5DM7H 1VQ4K 4IOAH 1VQ7K
chains in the Genus database with same CATH topology
3CCJK 5GAHL 4UY8K 2ZJQH 1Q81L 5AN9E 4WCEH 1S72K 3DLLH 3CCQK 1VQ6K 3CCUK 3CCVK 3PIOH 4V19O 1VQKK 3CD6K 4WF9H 3I55K 1YHQK 5GAGL 3OW2J 1VQMK 4IO9H 2QA4K 3I56K 4U67H 3CCLK 5GADL 1WHIA 1VQ8K 3CC4K 1Q86L 1K8AL 1M1KL 3CCMK 3CXCJ 4WFBH 3CC2K 1QVGJ 1YJ9K 1K9ML 4WFAH 1Q82L 5DM6H 5JVHH 1NJIL 1VQNK 3CPWJ 1VQ5K 1VQOK 5GAEL 3CC7K 3J7YL 3CCSK 3CMAK 3CF5H 3J7ZK 3G6EK 1YI2K 1QVFJ 1KD1L 5HL7H 3CCEK 1JJ2J 2ZJPH 1YIJK 4WFNH 1KQSJ 1YJWK 1VQPK 1W2BJ 3CMEK 5H1SM 4IOCH 1VQLK 3CCRK 1YJNK 2QEXK 3G71K 2OTLK 3G4SK 1K73L 2OTJK 3PIPH 2ZJRH 1M90L 1N8RL 1Q7YL 5MLCM 1VQ9K 5JVGH 1KC8L 1YITK 5DM7H 1VQ4K 4IOAH 1VQ7K
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCJ K;  5GAH L;  4UY8 K;  2ZJQ H;  1Q81 L;  5AN9 E;  4WCE H;  1S72 K;  3DLL H;  3CCQ K;  1VQ6 K;  3CCU K;  3CCV K;  3PIO H;  4V19 O;  1VQK K;  3CD6 K;  4WF9 H;  3I55 K;  1YHQ K;  5GAG L;  3OW2 J;  1VQM K;  4IO9 H;  2QA4 K;  3I56 K;  4U67 H;  3CCL K;  5GAD L;  1WHI A;  1VQ8 K;  3CC4 K;  1Q86 L;  1K8A L;  1M1K L;  3CCM K;  3CXC J;  4WFB H;  3CC2 K;  1QVG J;  1YJ9 K;  1K9M L;  4WFA H;  1Q82 L;  5DM6 H;  5JVH H;  1NJI L;  1VQN K;  3CPW J;  1VQ5 K;  1VQO K;  5GAE L;  3CC7 K;  3J7Y L;  3CCS K;  3CMA K;  3CF5 H;  3J7Z K;  3G6E K;  1YI2 K;  1QVF J;  1KD1 L;  5HL7 H;  3CCE K;  1JJ2 J;  2ZJP H;  1YIJ K;  4WFN H;  1KQS J;  1YJW K;  1VQP K;  1W2B J;  3CME K;  5H1S M;  4IOC H;  1VQL K;  3CCR K;  1YJN K;  2QEX K;  3G71 K;  2OTL K;  3G4S K;  1K73 L;  2OTJ K;  3PIP H;  2ZJR H;  1M90 L;  1N8R L;  1Q7Y L;  5MLC M;  1VQ9 K;  5JVG H;  1KC8 L;  1YIT K;  5DM7 H;  1VQ4 K;  4IOA H;  1VQ7 K; 
#chains in the Genus database with same CATH topology
 3CCJ K;  5GAH L;  4UY8 K;  2ZJQ H;  1Q81 L;  5AN9 E;  4WCE H;  1S72 K;  3DLL H;  3CCQ K;  1VQ6 K;  3CCU K;  3CCV K;  3PIO H;  4V19 O;  1VQK K;  3CD6 K;  4WF9 H;  3I55 K;  1YHQ K;  5GAG L;  3OW2 J;  1VQM K;  4IO9 H;  2QA4 K;  3I56 K;  4U67 H;  3CCL K;  5GAD L;  1WHI A;  1VQ8 K;  3CC4 K;  1Q86 L;  1K8A L;  1M1K L;  3CCM K;  3CXC J;  4WFB H;  3CC2 K;  1QVG J;  1YJ9 K;  1K9M L;  4WFA H;  1Q82 L;  5DM6 H;  5JVH H;  1NJI L;  1VQN K;  3CPW J;  1VQ5 K;  1VQO K;  5GAE L;  3CC7 K;  3J7Y L;  3CCS K;  3CMA K;  3CF5 H;  3J7Z K;  3G6E K;  1YI2 K;  1QVF J;  1KD1 L;  5HL7 H;  3CCE K;  1JJ2 J;  2ZJP H;  1YIJ K;  4WFN H;  1KQS J;  1YJW K;  1VQP K;  1W2B J;  3CME K;  5H1S M;  4IOC H;  1VQL K;  3CCR K;  1YJN K;  2QEX K;  3G71 K;  2OTL K;  3G4S K;  1K73 L;  2OTJ K;  3PIP H;  2ZJR H;  1M90 L;  1N8R L;  1Q7Y L;  5MLC M;  1VQ9 K;  5JVG H;  1KC8 L;  1YIT K;  5DM7 H;  1VQ4 K;  4IOA H;  1VQ7 K; 
#chains in the Genus database with same CATH homology
 3CCJ K;  5GAH L;  4UY8 K;  2ZJQ H;  1Q81 L;  5AN9 E;  4WCE H;  1S72 K;  3DLL H;  3CCQ K;  1VQ6 K;  3CCU K;  3CCV K;  3PIO H;  4V19 O;  1VQK K;  3CD6 K;  4WF9 H;  3I55 K;  1YHQ K;  5GAG L;  3OW2 J;  1VQM K;  4IO9 H;  2QA4 K;  3I56 K;  4U67 H;  3CCL K;  5GAD L;  1WHI A;  1VQ8 K;  3CC4 K;  1Q86 L;  1K8A L;  1M1K L;  3CCM K;  3CXC J;  4WFB H;  3CC2 K;  1QVG J;  1YJ9 K;  1K9M L;  4WFA H;  1Q82 L;  5DM6 H;  5JVH H;  1NJI L;  1VQN K;  3CPW J;  1VQ5 K;  1VQO K;  5GAE L;  3CC7 K;  3J7Y L;  3CCS K;  3CMA K;  3CF5 H;  3J7Z K;  3G6E K;  1YI2 K;  1QVF J;  1KD1 L;  5HL7 H;  3CCE K;  1JJ2 J;  2ZJP H;  1YIJ K;  4WFN H;  1KQS J;  1YJW K;  1VQP K;  1W2B J;  3CME K;  5H1S M;  4IOC H;  1VQL K;  3CCR K;  1YJN K;  2QEX K;  3G71 K;  2OTL K;  3G4S K;  1K73 L;  2OTJ K;  3PIP H;  2ZJR H;  1M90 L;  1N8R L;  1Q7Y L;  5MLC M;  1VQ9 K;  5JVG H;  1KC8 L;  1YIT K;  5DM7 H;  1VQ4 K;  4IOA H;  1VQ7 K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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