3CCVK

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
132
structure length
132
Chain Sequence
MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 29
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 3ccvK00
3CC7K 4WF9H 5GADL 3CMAK 1KD1L 1YJNK 2OTJK 1VQ7K 3PIOH 4IOAH 4V19O 5H1SM 1VQ9K 1YITK 2OTLK 5AN9E 2QA4K 3CCRK 3CCSK 1YIJK 1WHIA 4WCEH 1VQLK 3CCQK 1QVFJ 1N8RL 1KQSJ 1VQNK 4U67H 3PIPH 3I56K 3CCLK 3J7ZK 1K9ML 4IO9H 3G4SK 1YHQK 1VQOK 1S72K 3DLLH 1VQ8K 2ZJRH 4WFBH 1YJ9K 1Q81L 1VQ6K 3I55K 2ZJPH 3CCJK 3CCVK 5MLCM 3CF5H 5GAHL 3G6EK 1VQ4K 3CXCJ 5GAGL 1VQ5K 5HL7H 1M90L 3CC2K 3G71K 1NJIL 1K73L 1W2BJ 5DM6H 1KC8L 3CCEK 3OW2J 5GAEL 5JVGH 1M1KL 5DM7H 1Q86L 3CMEK 3CCMK 1VQKK 1Q7YL 1YI2K 3CD6K 2QEXK 1JJ2J 1VQPK 3CCUK 1VQMK 1YJWK 4WFAH 3CPWJ 4IOCH 1Q82L 3J7YL 4WFNH 4UY8K 1QVGJ 3CC4K 1K8AL 2ZJQH 5JVHH
chains in the Genus database with same CATH superfamily
3CC7K 4WF9H 5GADL 3CMAK 1KD1L 1YJNK 2OTJK 1VQ7K 3PIOH 4IOAH 4V19O 5H1SM 1VQ9K 1YITK 2OTLK 5AN9E 2QA4K 3CCRK 3CCSK 1YIJK 1WHIA 4WCEH 1VQLK 3CCQK 1QVFJ 1N8RL 1KQSJ 1VQNK 4U67H 3PIPH 3I56K 3CCLK 3J7ZK 1K9ML 4IO9H 3G4SK 1YHQK 1VQOK 1S72K 3DLLH 1VQ8K 2ZJRH 4WFBH 1YJ9K 1Q81L 1VQ6K 3I55K 2ZJPH 3CCJK 3CCVK 5MLCM 3CF5H 5GAHL 3G6EK 1VQ4K 3CXCJ 5GAGL 1VQ5K 5HL7H 1M90L 3CC2K 3G71K 1NJIL 1K73L 1W2BJ 5DM6H 1KC8L 3CCEK 3OW2J 5GAEL 5JVGH 1M1KL 5DM7H 1Q86L 3CMEK 3CCMK 1VQKK 1Q7YL 1YI2K 3CD6K 2QEXK 1JJ2J 1VQPK 3CCUK 1VQMK 1YJWK 4WFAH 3CPWJ 4IOCH 1Q82L 3J7YL 4WFNH 4UY8K 1QVGJ 3CC4K 1K8AL 2ZJQH 5JVHH
chains in the Genus database with same CATH topology
3CC7K 4WF9H 5GADL 3CMAK 1KD1L 1YJNK 2OTJK 1VQ7K 3PIOH 4IOAH 4V19O 5H1SM 1VQ9K 1YITK 2OTLK 5AN9E 2QA4K 3CCRK 3CCSK 1YIJK 1WHIA 4WCEH 1VQLK 3CCQK 1QVFJ 1N8RL 1KQSJ 1VQNK 4U67H 3PIPH 3I56K 3CCLK 3J7ZK 1K9ML 4IO9H 3G4SK 1YHQK 1VQOK 1S72K 3DLLH 1VQ8K 2ZJRH 4WFBH 1YJ9K 1Q81L 1VQ6K 3I55K 2ZJPH 3CCJK 3CCVK 5MLCM 3CF5H 5GAHL 3G6EK 1VQ4K 3CXCJ 5GAGL 1VQ5K 5HL7H 1M90L 3CC2K 3G71K 1NJIL 1K73L 1W2BJ 5DM6H 1KC8L 3CCEK 3OW2J 5GAEL 5JVGH 1M1KL 5DM7H 1Q86L 3CMEK 3CCMK 1VQKK 1Q7YL 1YI2K 3CD6K 2QEXK 1JJ2J 1VQPK 3CCUK 1VQMK 1YJWK 4WFAH 3CPWJ 4IOCH 1Q82L 3J7YL 4WFNH 4UY8K 1QVGJ 3CC4K 1K8AL 2ZJQH 5JVHH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CC7 K;  4WF9 H;  5GAD L;  3CMA K;  1KD1 L;  1YJN K;  2OTJ K;  1VQ7 K;  3PIO H;  4IOA H;  4V19 O;  5H1S M;  1VQ9 K;  1YIT K;  2OTL K;  5AN9 E;  2QA4 K;  3CCR K;  3CCS K;  1YIJ K;  1WHI A;  4WCE H;  1VQL K;  3CCQ K;  1QVF J;  1N8R L;  1KQS J;  1VQN K;  4U67 H;  3PIP H;  3I56 K;  3CCL K;  3J7Z K;  1K9M L;  4IO9 H;  3G4S K;  1YHQ K;  1VQO K;  1S72 K;  3DLL H;  1VQ8 K;  2ZJR H;  4WFB H;  1YJ9 K;  1Q81 L;  1VQ6 K;  3I55 K;  2ZJP H;  3CCJ K;  3CCV K;  5MLC M;  3CF5 H;  5GAH L;  3G6E K;  1VQ4 K;  3CXC J;  5GAG L;  1VQ5 K;  5HL7 H;  1M90 L;  3CC2 K;  3G71 K;  1NJI L;  1K73 L;  1W2B J;  5DM6 H;  1KC8 L;  3CCE K;  3OW2 J;  5GAE L;  5JVG H;  1M1K L;  5DM7 H;  1Q86 L;  3CME K;  3CCM K;  1VQK K;  1Q7Y L;  1YI2 K;  3CD6 K;  2QEX K;  1JJ2 J;  1VQP K;  3CCU K;  1VQM K;  1YJW K;  4WFA H;  3CPW J;  4IOC H;  1Q82 L;  3J7Y L;  4WFN H;  4UY8 K;  1QVG J;  3CC4 K;  1K8A L;  2ZJQ H;  5JVH H; 
#chains in the Genus database with same CATH topology
 3CC7 K;  4WF9 H;  5GAD L;  3CMA K;  1KD1 L;  1YJN K;  2OTJ K;  1VQ7 K;  3PIO H;  4IOA H;  4V19 O;  5H1S M;  1VQ9 K;  1YIT K;  2OTL K;  5AN9 E;  2QA4 K;  3CCR K;  3CCS K;  1YIJ K;  1WHI A;  4WCE H;  1VQL K;  3CCQ K;  1QVF J;  1N8R L;  1KQS J;  1VQN K;  4U67 H;  3PIP H;  3I56 K;  3CCL K;  3J7Z K;  1K9M L;  4IO9 H;  3G4S K;  1YHQ K;  1VQO K;  1S72 K;  3DLL H;  1VQ8 K;  2ZJR H;  4WFB H;  1YJ9 K;  1Q81 L;  1VQ6 K;  3I55 K;  2ZJP H;  3CCJ K;  3CCV K;  5MLC M;  3CF5 H;  5GAH L;  3G6E K;  1VQ4 K;  3CXC J;  5GAG L;  1VQ5 K;  5HL7 H;  1M90 L;  3CC2 K;  3G71 K;  1NJI L;  1K73 L;  1W2B J;  5DM6 H;  1KC8 L;  3CCE K;  3OW2 J;  5GAE L;  5JVG H;  1M1K L;  5DM7 H;  1Q86 L;  3CME K;  3CCM K;  1VQK K;  1Q7Y L;  1YI2 K;  3CD6 K;  2QEX K;  1JJ2 J;  1VQP K;  3CCU K;  1VQM K;  1YJW K;  4WFA H;  3CPW J;  4IOC H;  1Q82 L;  3J7Y L;  4WFN H;  4UY8 K;  1QVG J;  3CC4 K;  1K8A L;  2ZJQ H;  5JVH H; 
#chains in the Genus database with same CATH homology
 3CC7 K;  4WF9 H;  5GAD L;  3CMA K;  1KD1 L;  1YJN K;  2OTJ K;  1VQ7 K;  3PIO H;  4IOA H;  4V19 O;  5H1S M;  1VQ9 K;  1YIT K;  2OTL K;  5AN9 E;  2QA4 K;  3CCR K;  3CCS K;  1YIJ K;  1WHI A;  4WCE H;  1VQL K;  3CCQ K;  1QVF J;  1N8R L;  1KQS J;  1VQN K;  4U67 H;  3PIP H;  3I56 K;  3CCL K;  3J7Z K;  1K9M L;  4IO9 H;  3G4S K;  1YHQ K;  1VQO K;  1S72 K;  3DLL H;  1VQ8 K;  2ZJR H;  4WFB H;  1YJ9 K;  1Q81 L;  1VQ6 K;  3I55 K;  2ZJP H;  3CCJ K;  3CCV K;  5MLC M;  3CF5 H;  5GAH L;  3G6E K;  1VQ4 K;  3CXC J;  5GAG L;  1VQ5 K;  5HL7 H;  1M90 L;  3CC2 K;  3G71 K;  1NJI L;  1K73 L;  1W2B J;  5DM6 H;  1KC8 L;  3CCE K;  3OW2 J;  5GAE L;  5JVG H;  1M1K L;  5DM7 H;  1Q86 L;  3CME K;  3CCM K;  1VQK K;  1Q7Y L;  1YI2 K;  3CD6 K;  2QEX K;  1JJ2 J;  1VQP K;  3CCU K;  1VQM K;  1YJW K;  4WFA H;  3CPW J;  4IOC H;  1Q82 L;  3J7Y L;  4WFN H;  4UY8 K;  1QVG J;  3CC4 K;  1K8A L;  2ZJQ H;  5JVH H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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