3EAPA

Crystal structure of the rhogap domain of arhgap11a
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
257
structure length
225
Chain Sequence
LYFQGMWDQRLVRLALLQHLRAFYGIKVGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTSLEDHIHTSVIRLKALKNKVDHGSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGRVPDFILEKIPAM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the RhoGAP domain of ARHGAP11A
rcsb
molecule tags Hydrolase activator
source organism Homo sapiens
molecule keywords Rho GTPase-activating protein 11A
total genus 72
structure length 225
sequence length 257
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2008-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 3eapA00
3BYIA 2XS6A 3IUGA 3FK2A 2NGRB 2OSAA 3KUQA 3WPQA 2MBGA 1F7CA 2OVJA 5IRCA 1OW3A 5C5SA 1XA6A 5C2JA 3W6RA 5JCPA 3QISA 2QV2A 3MSXB 3EAPA 1GRNB 1TX4A 2EE5A 3CXLA 3WPSA 1AM4A 2EE4A 5JD0A 1PBWA 1RGPA 5HPYA
chains in the Genus database with same CATH superfamily
3BYIA 2XS6A 3IUGA 3FK2A 2NGRB 2OSAA 3KUQA 3WPQA 2MBGA 1F7CA 2OVJA 5IRCA 1OW3A 5C5SA 1XA6A 5C2JA 3W6RA 5JCPA 3QISA 2QV2A 3MSXB 3EAPA 1GRNB 1TX4A 2EE5A 3CXLA 3WPSA 1AM4A 2EE4A 5JD0A 1PBWA 1RGPA 5HPYA
chains in the Genus database with same CATH topology
3BYIA 2XS6A 3IUGA 3FK2A 2NGRB 2OSAA 3KUQA 3WPQA 2MBGA 1F7CA 2OVJA 5IRCA 1OW3A 5C5SA 1XA6A 5C2JA 3W6RA 5JCPA 3QISA 2QV2A 3MSXB 3EAPA 1GRNB 1TX4A 2EE5A 3CXLA 3WPSA 1AM4A 2EE4A 5JD0A 1PBWA 1RGPA 5HPYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BYI A;  2XS6 A;  3IUG A;  3FK2 A;  2NGR B;  2OSA A;  3KUQ A;  3WPQ A;  2MBG A;  1F7C A;  2OVJ A;  5IRC A;  1OW3 A;  5C5S A;  1XA6 A;  5C2J A;  3W6R A;  5JCP A;  3QIS A;  2QV2 A;  3MSX B;  3EAP A;  1GRN B;  1TX4 A;  2EE5 A;  3CXL A;  3WPS A;  1AM4 A;  2EE4 A;  5JD0 A;  1PBW A;  1RGP A;  5HPY A; 
#chains in the Genus database with same CATH topology
 3BYI A;  2XS6 A;  3IUG A;  3FK2 A;  2NGR B;  2OSA A;  3KUQ A;  3WPQ A;  2MBG A;  1F7C A;  2OVJ A;  5IRC A;  1OW3 A;  5C5S A;  1XA6 A;  5C2J A;  3W6R A;  5JCP A;  3QIS A;  2QV2 A;  3MSX B;  3EAP A;  1GRN B;  1TX4 A;  2EE5 A;  3CXL A;  3WPS A;  1AM4 A;  2EE4 A;  5JD0 A;  1PBW A;  1RGP A;  5HPY A; 
#chains in the Genus database with same CATH homology
 3BYI A;  2XS6 A;  3IUG A;  3FK2 A;  2NGR B;  2OSA A;  3KUQ A;  3WPQ A;  2MBG A;  1F7C A;  2OVJ A;  5IRC A;  1OW3 A;  5C5S A;  1XA6 A;  5C2J A;  3W6R A;  5JCP A;  3QIS A;  2QV2 A;  3MSX B;  3EAP A;  1GRN B;  1TX4 A;  2EE5 A;  3CXL A;  3WPS A;  1AM4 A;  2EE4 A;  5JD0 A;  1PBW A;  1RGP A;  5HPY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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