3G4SK

Co-crystal structure of tiamulin bound to the large ribosomal subunit
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
132
structure length
132
Chain Sequence
MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 27
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2009-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 3g4sK00
5HL7H 1Q82L 5GADL 4WFBH 1S72K 1KC8L 1KQSJ 1K9ML 3CCEK 5GAGL 1KD1L 3CD6K 1VQPK 4WCEH 3OW2J 3G6EK 2ZJRH 5DM6H 1VQ6K 1M90L 3CCVK 1QVFJ 5H1SM 1WHIA 3G71K 1Q86L 1Q81L 3CCQK 1VQMK 3CMAK 2OTJK 5AN9E 1Q7YL 1YI2K 3CCRK 3CCMK 1VQKK 3J7ZK 1YJWK 3CC4K 4WFAH 2ZJPH 1YHQK 2ZJQH 1N8RL 1QVGJ 4V19O 4WF9H 4IOCH 1YJ9K 5GAHL 5MLCM 3J7YL 4UY8K 2QEXK 1K73L 3CXCJ 3CPWJ 4U67H 1VQ4K 4IO9H 1NJIL 3CCSK 4IOAH 3CCJK 5DM7H 3PIOH 3CC2K 1VQ8K 1YIJK 1VQLK 5JVGH 3CMEK 1YJNK 1K8AL 3CCUK 3CF5H 1M1KL 3PIPH 3I55K 1VQOK 2OTLK 3CCLK 3I56K 1VQ9K 2QA4K 1VQ5K 1JJ2J 5JVHH 1W2BJ 4WFNH 1YITK 3CC7K 5GAEL 3G4SK 1VQNK 3DLLH 1VQ7K
chains in the Genus database with same CATH superfamily
5HL7H 1Q82L 5GADL 4WFBH 1S72K 1KC8L 1KQSJ 1K9ML 3CCEK 5GAGL 1KD1L 3CD6K 1VQPK 4WCEH 3OW2J 3G6EK 2ZJRH 5DM6H 1VQ6K 1M90L 3CCVK 1QVFJ 5H1SM 1WHIA 3G71K 1Q86L 1Q81L 3CCQK 1VQMK 3CMAK 2OTJK 5AN9E 1Q7YL 1YI2K 3CCRK 3CCMK 1VQKK 3J7ZK 1YJWK 3CC4K 4WFAH 2ZJPH 1YHQK 2ZJQH 1N8RL 1QVGJ 4V19O 4WF9H 4IOCH 1YJ9K 5GAHL 5MLCM 3J7YL 4UY8K 2QEXK 1K73L 3CXCJ 3CPWJ 4U67H 1VQ4K 4IO9H 1NJIL 3CCSK 4IOAH 3CCJK 5DM7H 3PIOH 3CC2K 1VQ8K 1YIJK 1VQLK 5JVGH 3CMEK 1YJNK 1K8AL 3CCUK 3CF5H 1M1KL 3PIPH 3I55K 1VQOK 2OTLK 3CCLK 3I56K 1VQ9K 2QA4K 1VQ5K 1JJ2J 5JVHH 1W2BJ 4WFNH 1YITK 3CC7K 5GAEL 3G4SK 1VQNK 3DLLH 1VQ7K
chains in the Genus database with same CATH topology
5HL7H 1Q82L 5GADL 4WFBH 1S72K 1KC8L 1KQSJ 1K9ML 3CCEK 5GAGL 1KD1L 3CD6K 1VQPK 4WCEH 3OW2J 3G6EK 2ZJRH 5DM6H 1VQ6K 1M90L 3CCVK 1QVFJ 5H1SM 1WHIA 3G71K 1Q86L 1Q81L 3CCQK 1VQMK 3CMAK 2OTJK 5AN9E 1Q7YL 1YI2K 3CCRK 3CCMK 1VQKK 3J7ZK 1YJWK 3CC4K 4WFAH 2ZJPH 1YHQK 2ZJQH 1N8RL 1QVGJ 4V19O 4WF9H 4IOCH 1YJ9K 5GAHL 5MLCM 3J7YL 4UY8K 2QEXK 1K73L 3CXCJ 3CPWJ 4U67H 1VQ4K 4IO9H 1NJIL 3CCSK 4IOAH 3CCJK 5DM7H 3PIOH 3CC2K 1VQ8K 1YIJK 1VQLK 5JVGH 3CMEK 1YJNK 1K8AL 3CCUK 3CF5H 1M1KL 3PIPH 3I55K 1VQOK 2OTLK 3CCLK 3I56K 1VQ9K 2QA4K 1VQ5K 1JJ2J 5JVHH 1W2BJ 4WFNH 1YITK 3CC7K 5GAEL 3G4SK 1VQNK 3DLLH 1VQ7K
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HL7 H;  1Q82 L;  5GAD L;  4WFB H;  1S72 K;  1KC8 L;  1KQS J;  1K9M L;  3CCE K;  5GAG L;  1KD1 L;  3CD6 K;  1VQP K;  4WCE H;  3OW2 J;  3G6E K;  2ZJR H;  5DM6 H;  1VQ6 K;  1M90 L;  3CCV K;  1QVF J;  5H1S M;  1WHI A;  3G71 K;  1Q86 L;  1Q81 L;  3CCQ K;  1VQM K;  3CMA K;  2OTJ K;  5AN9 E;  1Q7Y L;  1YI2 K;  3CCR K;  3CCM K;  1VQK K;  3J7Z K;  1YJW K;  3CC4 K;  4WFA H;  2ZJP H;  1YHQ K;  2ZJQ H;  1N8R L;  1QVG J;  4V19 O;  4WF9 H;  4IOC H;  1YJ9 K;  5GAH L;  5MLC M;  3J7Y L;  4UY8 K;  2QEX K;  1K73 L;  3CXC J;  3CPW J;  4U67 H;  1VQ4 K;  4IO9 H;  1NJI L;  3CCS K;  4IOA H;  3CCJ K;  5DM7 H;  3PIO H;  3CC2 K;  1VQ8 K;  1YIJ K;  1VQL K;  5JVG H;  3CME K;  1YJN K;  1K8A L;  3CCU K;  3CF5 H;  1M1K L;  3PIP H;  3I55 K;  1VQO K;  2OTL K;  3CCL K;  3I56 K;  1VQ9 K;  2QA4 K;  1VQ5 K;  1JJ2 J;  5JVH H;  1W2B J;  4WFN H;  1YIT K;  3CC7 K;  5GAE L;  3G4S K;  1VQN K;  3DLL H;  1VQ7 K; 
#chains in the Genus database with same CATH topology
 5HL7 H;  1Q82 L;  5GAD L;  4WFB H;  1S72 K;  1KC8 L;  1KQS J;  1K9M L;  3CCE K;  5GAG L;  1KD1 L;  3CD6 K;  1VQP K;  4WCE H;  3OW2 J;  3G6E K;  2ZJR H;  5DM6 H;  1VQ6 K;  1M90 L;  3CCV K;  1QVF J;  5H1S M;  1WHI A;  3G71 K;  1Q86 L;  1Q81 L;  3CCQ K;  1VQM K;  3CMA K;  2OTJ K;  5AN9 E;  1Q7Y L;  1YI2 K;  3CCR K;  3CCM K;  1VQK K;  3J7Z K;  1YJW K;  3CC4 K;  4WFA H;  2ZJP H;  1YHQ K;  2ZJQ H;  1N8R L;  1QVG J;  4V19 O;  4WF9 H;  4IOC H;  1YJ9 K;  5GAH L;  5MLC M;  3J7Y L;  4UY8 K;  2QEX K;  1K73 L;  3CXC J;  3CPW J;  4U67 H;  1VQ4 K;  4IO9 H;  1NJI L;  3CCS K;  4IOA H;  3CCJ K;  5DM7 H;  3PIO H;  3CC2 K;  1VQ8 K;  1YIJ K;  1VQL K;  5JVG H;  3CME K;  1YJN K;  1K8A L;  3CCU K;  3CF5 H;  1M1K L;  3PIP H;  3I55 K;  1VQO K;  2OTL K;  3CCL K;  3I56 K;  1VQ9 K;  2QA4 K;  1VQ5 K;  1JJ2 J;  5JVH H;  1W2B J;  4WFN H;  1YIT K;  3CC7 K;  5GAE L;  3G4S K;  1VQN K;  3DLL H;  1VQ7 K; 
#chains in the Genus database with same CATH homology
 5HL7 H;  1Q82 L;  5GAD L;  4WFB H;  1S72 K;  1KC8 L;  1KQS J;  1K9M L;  3CCE K;  5GAG L;  1KD1 L;  3CD6 K;  1VQP K;  4WCE H;  3OW2 J;  3G6E K;  2ZJR H;  5DM6 H;  1VQ6 K;  1M90 L;  3CCV K;  1QVF J;  5H1S M;  1WHI A;  3G71 K;  1Q86 L;  1Q81 L;  3CCQ K;  1VQM K;  3CMA K;  2OTJ K;  5AN9 E;  1Q7Y L;  1YI2 K;  3CCR K;  3CCM K;  1VQK K;  3J7Z K;  1YJW K;  3CC4 K;  4WFA H;  2ZJP H;  1YHQ K;  2ZJQ H;  1N8R L;  1QVG J;  4V19 O;  4WF9 H;  4IOC H;  1YJ9 K;  5GAH L;  5MLC M;  3J7Y L;  4UY8 K;  2QEX K;  1K73 L;  3CXC J;  3CPW J;  4U67 H;  1VQ4 K;  4IO9 H;  1NJI L;  3CCS K;  4IOA H;  3CCJ K;  5DM7 H;  3PIO H;  3CC2 K;  1VQ8 K;  1YIJ K;  1VQL K;  5JVG H;  3CME K;  1YJN K;  1K8A L;  3CCU K;  3CF5 H;  1M1K L;  3PIP H;  3I55 K;  1VQO K;  2OTL K;  3CCL K;  3I56 K;  1VQ9 K;  2QA4 K;  1VQ5 K;  1JJ2 J;  5JVH H;  1W2B J;  4WFN H;  1YIT K;  3CC7 K;  5GAE L;  3G4S K;  1VQN K;  3DLL H;  1VQ7 K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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