3HRDA

Crystal structure of nicotinate dehydrogenase
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
420
structure length
420
Chain Sequence
GKDYQVLGKNKVKVDSLEKVMGTAKFAADYSFPDMLYAGVFRSTVPHARIVSLDLSKARAIDGVEAVLDYHAIPGKNRFGIIIKDEPCLVDDKVRRYGDAIAVVAAQTPDLVQEALDAITIEYEELEGIFTMERALEEDSPAIHGDTNIHQVKHLEYGDVDAAFKQCDIVVEDTYSTHRLTHMFIEPDAGVSYYDNEGMLTVVVSTQNPHYDRGEVAGMLALPNSKVRIIQATTGGGFGGKLDLSVQCHCALLTYHTKKPVKMVRSREESTTVSSKRHPMTMHCKTGATKDGRLQAVQVEMFGDTGAYASYGPAVITRATVHCMGPYVVPNVRVDAKFVYTNNPMSGAFRGFGVPQASVCHEGQMNALAKALGMDPIDIRILNAHQVGAKLATGQVLENSVGLIETLEKAREKAVEVMGY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
publication title The Mo-Se active site of nicotinate dehydrogenase
pubmed doi rcsb
molecule keywords Nicotinate dehydrogenase large molybdopterin subunit
total genus 135
structure length 420
sequence length 420
chains with identical sequence E
ec nomenclature ec 1.17.1.5: Nicotinate dehydrogenase.
pdb deposition date 2009-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01315 Ald_Xan_dh_C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
A PF02738 Ald_Xan_dh_C2 Molybdopterin-binding domain of aldehyde dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 3hrdA02
2W3SB 3NRZC 1SB3A 2W55B 1SIJA 4ZOHA 1FFVB 1N5WB 1V97A 3B9JC 1FFUB 3L4PA 4C7ZA 1JRPB 1VLBA 1VDVA 4US9A 4C7YA 4USAA 3NVWC 3EUB4 2W3RB 1N61B 3FC4A 3NVYC 3HRDA 1DGJA 3SR6C 1FIQC 3NS1C 3NVZC 1JROB 3FAHA 1N63B 4C80A 1ZXIB 2W54B 4US8A 1FO4A 1RM6A 2E3TA 1N60B 3AN1A 3ETRC 3HRDB 3AM9A 1N5XA 3NVVC 1N62B 3AMZA 1WYGA
chains in the Genus database with same CATH superfamily
2W3SB 3NRZC 1SB3A 2W55B 1SIJA 4ZOHA 1FFVB 1N5WB 1V97A 3B9JC 1FFUB 3L4PA 4C7ZA 1JRPB 1VLBA 1VDVA 4US9A 4C7YA 4USAA 3NVWC 3EUB4 2W3RB 1N61B 3FC4A 3NVYC 3HRDA 1DGJA 3SR6C 1FIQC 3NS1C 3NVZC 1JROB 3FAHA 1N63B 4C80A 1ZXIB 2W54B 4US8A 1FO4A 1RM6A 2E3TA 1N60B 3AN1A 3ETRC 1T3QB 3HRDB 3AM9A 1N5XA 3NVVC 1N62B 3AMZA 1WYGA
chains in the Genus database with same CATH topology
2W3SB 3NRZC 1SB3A 2W55B 1SIJA 4ZOHA 1FFVB 1N5WB 1V97A 3B9JC 1FFUB 3L4PA 4C7ZA 1JRPB 1VLBA 1VDVA 4US9A 4C7YA 4USAA 3NVWC 3EUB4 2W3RB 1N61B 3FC4A 3NVYC 3HRDA 1DGJA 3SR6C 1FIQC 3NS1C 3NVZC 1JROB 3FAHA 1N63B 4C80A 1ZXIB 2W54B 4US8A 1FO4A 1RM6A 2E3TA 1N60B 3AN1A 3ETRC 3HRDB 3AM9A 1N5XA 3NVVC 1N62B 3AMZA 1WYGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W3S B;  3NRZ C;  1SB3 A;  2W55 B;  1SIJ A;  4ZOH A;  1FFV B;  1N5W B;  1V97 A;  3B9J C;  1FFU B;  3L4P A;  4C7Z A;  1JRP B;  1VLB A;  1VDV A;  4US9 A;  4C7Y A;  4USA A;  3NVW C;  3EUB 4;  2W3R B;  1N61 B;  3FC4 A;  3NVY C;  3HRD A;  1DGJ A;  3SR6 C;  1FIQ C;  3NS1 C;  3NVZ C;  1JRO B;  3FAH A;  1N63 B;  4C80 A;  1ZXI B;  2W54 B;  4US8 A;  1FO4 A;  1RM6 A;  2E3T A;  1N60 B;  3AN1 A;  3ETR C;  3HRD B;  3AM9 A;  1N5X A;  3NVV C;  1N62 B;  3AMZ A;  1WYG A; 
#chains in the Genus database with same CATH topology
 2W3S B;  3NRZ C;  1SB3 A;  2W55 B;  1SIJ A;  4ZOH A;  1FFV B;  1N5W B;  1V97 A;  3B9J C;  1FFU B;  3L4P A;  4C7Z A;  1JRP B;  1VLB A;  1VDV A;  4US9 A;  4C7Y A;  4USA A;  3NVW C;  3EUB 4;  2W3R B;  1N61 B;  3FC4 A;  3NVY C;  3HRD A;  1DGJ A;  3SR6 C;  1FIQ C;  3NS1 C;  3NVZ C;  1JRO B;  3FAH A;  1N63 B;  4C80 A;  1ZXI B;  2W54 B;  4US8 A;  1FO4 A;  1RM6 A;  2E3T A;  1N60 B;  3AN1 A;  3ETR C;  1T3Q B;  3HRD B;  3AM9 A;  1N5X A;  3NVV C;  1N62 B;  3AMZ A;  1WYG A; 
#chains in the Genus database with same CATH homology
 2W3S B;  3NRZ C;  1SB3 A;  2W55 B;  1SIJ A;  4ZOH A;  1FFV B;  1N5W B;  1V97 A;  3B9J C;  1FFU B;  3L4P A;  4C7Z A;  1JRP B;  1VLB A;  1VDV A;  4US9 A;  4C7Y A;  4USA A;  3NVW C;  3EUB 4;  2W3R B;  1N61 B;  3FC4 A;  3NVY C;  3HRD A;  1DGJ A;  3SR6 C;  1FIQ C;  3NS1 C;  3NVZ C;  1JRO B;  3FAH A;  1N63 B;  4C80 A;  1ZXI B;  2W54 B;  4US8 A;  1FO4 A;  1RM6 A;  2E3T A;  1N60 B;  3AN1 A;  3ETR C;  3HRD B;  3AM9 A;  1N5X A;  3NVV C;  1N62 B;  3AMZ A;  1WYG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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