3IUGA

Crystal structure of the rhogap domain of rics
Total Genus 66
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
203
structure length
184
Chain Sequence
GERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSQSVVVEFILNHVDVLFS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the RhoGAP domain of RICS
rcsb
molecule keywords Rho/Cdc42/Rac GTPase-activating protein RICS
molecule tags Splicing
source organism Homo sapiens
total genus 66
structure length 184
sequence length 203
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 3iugA00
3EAPA 5IRCA 2EE5A 3QISA 5HPYA 2XS6A 3MSXB 3BYIA 3IUGA 1GRNB 1RGPA 2QV2A 3FK2A 5C2JA 5C5SA 1XA6A 5JD0A 1OW3A 2OVJA 3WPSA 3KUQA 3CXLA 2OSAA 1TX4A 5JCPA 3W6RA 3WPQA 1PBWA 1F7CA 2NGRB 2EE4A 2MBGA 1AM4A
chains in the Genus database with same CATH superfamily
3EAPA 5IRCA 2EE5A 3QISA 5HPYA 2XS6A 3MSXB 3BYIA 3IUGA 1GRNB 1RGPA 2QV2A 3FK2A 5C2JA 5C5SA 1XA6A 5JD0A 1OW3A 2OVJA 3WPSA 3KUQA 3CXLA 2OSAA 1TX4A 5JCPA 3W6RA 3WPQA 1PBWA 1F7CA 2NGRB 2EE4A 2MBGA 1AM4A
chains in the Genus database with same CATH topology
3EAPA 5IRCA 2EE5A 3QISA 5HPYA 2XS6A 3MSXB 3BYIA 3IUGA 1GRNB 1RGPA 2QV2A 3FK2A 5C2JA 5C5SA 1XA6A 5JD0A 1OW3A 2OVJA 3WPSA 3KUQA 3CXLA 2OSAA 1TX4A 5JCPA 3W6RA 3WPQA 1PBWA 1F7CA 2NGRB 2EE4A 2MBGA 1AM4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EAP A;  5IRC A;  2EE5 A;  3QIS A;  5HPY A;  2XS6 A;  3MSX B;  3BYI A;  3IUG A;  1GRN B;  1RGP A;  2QV2 A;  3FK2 A;  5C2J A;  5C5S A;  1XA6 A;  5JD0 A;  1OW3 A;  2OVJ A;  3WPS A;  3KUQ A;  3CXL A;  2OSA A;  1TX4 A;  5JCP A;  3W6R A;  3WPQ A;  1PBW A;  1F7C A;  2NGR B;  2EE4 A;  2MBG A;  1AM4 A; 
#chains in the Genus database with same CATH topology
 3EAP A;  5IRC A;  2EE5 A;  3QIS A;  5HPY A;  2XS6 A;  3MSX B;  3BYI A;  3IUG A;  1GRN B;  1RGP A;  2QV2 A;  3FK2 A;  5C2J A;  5C5S A;  1XA6 A;  5JD0 A;  1OW3 A;  2OVJ A;  3WPS A;  3KUQ A;  3CXL A;  2OSA A;  1TX4 A;  5JCP A;  3W6R A;  3WPQ A;  1PBW A;  1F7C A;  2NGR B;  2EE4 A;  2MBG A;  1AM4 A; 
#chains in the Genus database with same CATH homology
 3EAP A;  5IRC A;  2EE5 A;  3QIS A;  5HPY A;  2XS6 A;  3MSX B;  3BYI A;  3IUG A;  1GRN B;  1RGP A;  2QV2 A;  3FK2 A;  5C2J A;  5C5S A;  1XA6 A;  5JD0 A;  1OW3 A;  2OVJ A;  3WPS A;  3KUQ A;  3CXL A;  2OSA A;  1TX4 A;  5JCP A;  3W6R A;  3WPQ A;  1PBW A;  1F7C A;  2NGR B;  2EE4 A;  2MBG A;  1AM4 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...