3IUGA

Crystal structure of the rhogap domain of rics
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
203
structure length
184
Chain Sequence
GERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSQSVVVEFILNHVDVLFS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the RhoGAP domain of RICS
rcsb
molecule tags Splicing
source organism Homo sapiens
molecule keywords Rho/Cdc42/Rac GTPase-activating protein RICS
total genus 66
structure length 184
sequence length 203
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 3iugA00
1F7CA 2MBGA 1GRNB 5C5SA 3KUQA 2EE4A 5C2JA 2OVJA 3WPQA 1OW3A 3CXLA 2EE5A 5IRCA 3FK2A 3IUGA 3QISA 5HPYA 5JD0A 3W6RA 1AM4A 3EAPA 2XS6A 1RGPA 1TX4A 2OSAA 1PBWA 5JCPA 1XA6A 3WPSA 3MSXB 3BYIA 2QV2A 2NGRB
chains in the Genus database with same CATH superfamily
1F7CA 2MBGA 1GRNB 5C5SA 3KUQA 2EE4A 5C2JA 2OVJA 3WPQA 1OW3A 3CXLA 2EE5A 5IRCA 3FK2A 3IUGA 3QISA 5HPYA 5JD0A 3W6RA 1AM4A 3EAPA 2XS6A 1RGPA 1TX4A 2OSAA 1PBWA 5JCPA 1XA6A 3WPSA 3MSXB 3BYIA 2QV2A 2NGRB
chains in the Genus database with same CATH topology
1F7CA 2MBGA 1GRNB 5C5SA 3KUQA 2EE4A 5C2JA 2OVJA 3WPQA 1OW3A 3CXLA 2EE5A 5IRCA 3FK2A 3IUGA 3QISA 5HPYA 5JD0A 3W6RA 1AM4A 3EAPA 2XS6A 1RGPA 1TX4A 2OSAA 1PBWA 5JCPA 1XA6A 3WPSA 3MSXB 3BYIA 2QV2A 2NGRB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F7C A;  2MBG A;  1GRN B;  5C5S A;  3KUQ A;  2EE4 A;  5C2J A;  2OVJ A;  3WPQ A;  1OW3 A;  3CXL A;  2EE5 A;  5IRC A;  3FK2 A;  3IUG A;  3QIS A;  5HPY A;  5JD0 A;  3W6R A;  1AM4 A;  3EAP A;  2XS6 A;  1RGP A;  1TX4 A;  2OSA A;  1PBW A;  5JCP A;  1XA6 A;  3WPS A;  3MSX B;  3BYI A;  2QV2 A;  2NGR B; 
#chains in the Genus database with same CATH topology
 1F7C A;  2MBG A;  1GRN B;  5C5S A;  3KUQ A;  2EE4 A;  5C2J A;  2OVJ A;  3WPQ A;  1OW3 A;  3CXL A;  2EE5 A;  5IRC A;  3FK2 A;  3IUG A;  3QIS A;  5HPY A;  5JD0 A;  3W6R A;  1AM4 A;  3EAP A;  2XS6 A;  1RGP A;  1TX4 A;  2OSA A;  1PBW A;  5JCP A;  1XA6 A;  3WPS A;  3MSX B;  3BYI A;  2QV2 A;  2NGR B; 
#chains in the Genus database with same CATH homology
 1F7C A;  2MBG A;  1GRN B;  5C5S A;  3KUQ A;  2EE4 A;  5C2J A;  2OVJ A;  3WPQ A;  1OW3 A;  3CXL A;  2EE5 A;  5IRC A;  3FK2 A;  3IUG A;  3QIS A;  5HPY A;  5JD0 A;  3W6R A;  1AM4 A;  3EAP A;  2XS6 A;  1RGP A;  1TX4 A;  2OSA A;  1PBW A;  5JCP A;  1XA6 A;  3WPS A;  3MSX B;  3BYI A;  2QV2 A;  2NGR B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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