3MSXB

Crystal structure of rhoa.gdp.mgf3 in complex with gap domain of arhgap20
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
192
structure length
192
Chain Sequence
GQLFGISLPNICENDNLPKPVLDMLFFLNQKGPLTKGIFRQSANVKSCRELKEKLNSGVEVHLDCESIFVIASVLKDFLRNIPGSIFSSDLYDHWVSVMDQGNDEEKINTVQRLLDQLPRANVVLLRYLFGVLHNIEQHSSSNQMTAFNLAVCVAPSILWPPASSSPELENEFTKKVSLLIQFLIENCLRIF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanism of molecular specificity of RhoGAP domains towards small GTPases of RhoA family.
rcsb
molecule keywords Transforming protein RhoA
molecule tags Protein binding
source organism Homo sapiens
total genus 69
structure length 192
sequence length 192
ec nomenclature
pdb deposition date 2010-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 3msxB00
3EAPA 3IUGA 3QISA 3FK2A 1RGPA 2EE5A 3MSXB 5JCPA 2OVJA 1TX4A 3WPQA 3WPSA 5HPYA 5C5SA 2NGRB 1OW3A 2EE4A 2MBGA 5C2JA 2OSAA 3KUQA 1F7CA 5JD0A 5IRCA 2XS6A 3BYIA 3W6RA 1XA6A 1AM4A 3CXLA 1GRNB 1PBWA 2QV2A
chains in the Genus database with same CATH superfamily
3EAPA 3IUGA 3QISA 3FK2A 1RGPA 2EE5A 3MSXB 5JCPA 2OVJA 1TX4A 3WPQA 3WPSA 5HPYA 5C5SA 2NGRB 1OW3A 2EE4A 2MBGA 5C2JA 2OSAA 3KUQA 1F7CA 5JD0A 5IRCA 2XS6A 3BYIA 3W6RA 1XA6A 1AM4A 3CXLA 1GRNB 1PBWA 2QV2A
chains in the Genus database with same CATH topology
3EAPA 3IUGA 3QISA 3FK2A 1RGPA 2EE5A 3MSXB 5JCPA 2OVJA 1TX4A 3WPQA 3WPSA 5HPYA 5C5SA 2NGRB 1OW3A 2EE4A 2MBGA 5C2JA 2OSAA 3KUQA 1F7CA 5JD0A 5IRCA 2XS6A 3BYIA 3W6RA 1XA6A 1AM4A 3CXLA 1GRNB 1PBWA 2QV2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EAP A;  3IUG A;  3QIS A;  3FK2 A;  1RGP A;  2EE5 A;  3MSX B;  5JCP A;  2OVJ A;  1TX4 A;  3WPQ A;  3WPS A;  5HPY A;  5C5S A;  2NGR B;  1OW3 A;  2EE4 A;  2MBG A;  5C2J A;  2OSA A;  3KUQ A;  1F7C A;  5JD0 A;  5IRC A;  2XS6 A;  3BYI A;  3W6R A;  1XA6 A;  1AM4 A;  3CXL A;  1GRN B;  1PBW A;  2QV2 A; 
#chains in the Genus database with same CATH topology
 3EAP A;  3IUG A;  3QIS A;  3FK2 A;  1RGP A;  2EE5 A;  3MSX B;  5JCP A;  2OVJ A;  1TX4 A;  3WPQ A;  3WPS A;  5HPY A;  5C5S A;  2NGR B;  1OW3 A;  2EE4 A;  2MBG A;  5C2J A;  2OSA A;  3KUQ A;  1F7C A;  5JD0 A;  5IRC A;  2XS6 A;  3BYI A;  3W6R A;  1XA6 A;  1AM4 A;  3CXL A;  1GRN B;  1PBW A;  2QV2 A; 
#chains in the Genus database with same CATH homology
 3EAP A;  3IUG A;  3QIS A;  3FK2 A;  1RGP A;  2EE5 A;  3MSX B;  5JCP A;  2OVJ A;  1TX4 A;  3WPQ A;  3WPS A;  5HPY A;  5C5S A;  2NGR B;  1OW3 A;  2EE4 A;  2MBG A;  5C2J A;  2OSA A;  3KUQ A;  1F7C A;  5JD0 A;  5IRC A;  2XS6 A;  3BYI A;  3W6R A;  1XA6 A;  1AM4 A;  3CXL A;  1GRN B;  1PBW A;  2QV2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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