3PIPH

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
134
structure length
134
Chain Sequence
MIMPQSRLDVADNSGAREIMCIRVLNSGIGGKGLTTGGGGNKRYAHVGDIIVASVKDAAPRGAVKAGDVVKAVVVRTSHAIKRADGSTIRFDRNAAVIINNQGEPRGTRVFGPVARELRDRRFMKIVSLAPEVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 22
structure length 134
sequence length 134
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 3pipH00
1K73L 3CCEK 4U67H 4IO9H 2QA4K 1VQ6K 3J7YL 5DM6H 1VQLK 1YHQK 1VQ7K 4WFNH 3CCJK 3G4SK 1VQNK 2OTJK 3DLLH 1Q81L 2ZJPH 5GADL 3CC7K 3J7ZK 3CPWJ 1VQ4K 1M90L 2OTLK 2ZJRH 1KQSJ 3CD6K 4WF9H 1YIJK 1Q86L 3G71K 3PIPH 1QVGJ 3CCVK 3CCMK 3CCLK 4WFBH 5GAHL 3CXCJ 1KC8L 3CF5H 1Q82L 5DM7H 1N8RL 1W2BJ 3CC4K 4V19O 1YJ9K 1VQOK 4UY8K 1YITK 3CCUK 2QEXK 1NJIL 5GAEL 3I55K 1QVFJ 5JVGH 3G6EK 3I56K 5H1SM 4WFAH 1YJNK 5AN9E 1VQ9K 4IOCH 1WHIA 3OW2J 3CCSK 1VQ8K 5JVHH 5HL7H 5GAGL 1M1KL 1K9ML 1VQKK 1YJWK 1VQPK 4IOAH 4WCEH 1S72K 2ZJQH 1K8AL 1YI2K 5MLCM 3PIOH 3CMAK 3CMEK 3CCRK 1Q7YL 1VQMK 3CC2K 1VQ5K 1KD1L 1JJ2J 3CCQK
chains in the Genus database with same CATH superfamily
1K73L 3CCEK 4U67H 4IO9H 2QA4K 1VQ6K 3J7YL 5DM6H 1VQLK 1YHQK 1VQ7K 4WFNH 3CCJK 3G4SK 1VQNK 2OTJK 3DLLH 1Q81L 2ZJPH 5GADL 3CC7K 3J7ZK 3CPWJ 1VQ4K 1M90L 2OTLK 2ZJRH 1KQSJ 3CD6K 4WF9H 1YIJK 1Q86L 3G71K 3PIPH 1QVGJ 3CCVK 3CCMK 3CCLK 4WFBH 5GAHL 3CXCJ 1KC8L 3CF5H 1Q82L 5DM7H 1N8RL 1W2BJ 3CC4K 4V19O 1YJ9K 1VQOK 4UY8K 1YITK 3CCUK 2QEXK 1NJIL 5GAEL 3I55K 1QVFJ 5JVGH 3G6EK 3I56K 5H1SM 4WFAH 1YJNK 5AN9E 1VQ9K 4IOCH 1WHIA 3OW2J 3CCSK 1VQ8K 5JVHH 5HL7H 5GAGL 1M1KL 1K9ML 1VQKK 1YJWK 1VQPK 4IOAH 4WCEH 1S72K 2ZJQH 1K8AL 1YI2K 5MLCM 3PIOH 3CMAK 3CMEK 3CCRK 1Q7YL 1VQMK 3CC2K 1VQ5K 1KD1L 1JJ2J 3CCQK
chains in the Genus database with same CATH topology
1K73L 3CCEK 4U67H 4IO9H 2QA4K 1VQ6K 3J7YL 5DM6H 1VQLK 1YHQK 1VQ7K 4WFNH 3CCJK 3G4SK 1VQNK 2OTJK 3DLLH 1Q81L 2ZJPH 5GADL 3CC7K 3J7ZK 3CPWJ 1VQ4K 1M90L 2OTLK 2ZJRH 1KQSJ 3CD6K 4WF9H 1YIJK 1Q86L 3G71K 3PIPH 1QVGJ 3CCVK 3CCMK 3CCLK 4WFBH 5GAHL 3CXCJ 1KC8L 3CF5H 1Q82L 5DM7H 1N8RL 1W2BJ 3CC4K 4V19O 1YJ9K 1VQOK 4UY8K 1YITK 3CCUK 2QEXK 1NJIL 5GAEL 3I55K 1QVFJ 5JVGH 3G6EK 3I56K 5H1SM 4WFAH 1YJNK 5AN9E 1VQ9K 4IOCH 1WHIA 3OW2J 3CCSK 1VQ8K 5JVHH 5HL7H 5GAGL 1M1KL 1K9ML 1VQKK 1YJWK 1VQPK 4IOAH 4WCEH 1S72K 2ZJQH 1K8AL 1YI2K 5MLCM 3PIOH 3CMAK 3CMEK 3CCRK 1Q7YL 1VQMK 3CC2K 1VQ5K 1KD1L 1JJ2J 3CCQK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K73 L;  3CCE K;  4U67 H;  4IO9 H;  2QA4 K;  1VQ6 K;  3J7Y L;  5DM6 H;  1VQL K;  1YHQ K;  1VQ7 K;  4WFN H;  3CCJ K;  3G4S K;  1VQN K;  2OTJ K;  3DLL H;  1Q81 L;  2ZJP H;  5GAD L;  3CC7 K;  3J7Z K;  3CPW J;  1VQ4 K;  1M90 L;  2OTL K;  2ZJR H;  1KQS J;  3CD6 K;  4WF9 H;  1YIJ K;  1Q86 L;  3G71 K;  3PIP H;  1QVG J;  3CCV K;  3CCM K;  3CCL K;  4WFB H;  5GAH L;  3CXC J;  1KC8 L;  3CF5 H;  1Q82 L;  5DM7 H;  1N8R L;  1W2B J;  3CC4 K;  4V19 O;  1YJ9 K;  1VQO K;  4UY8 K;  1YIT K;  3CCU K;  2QEX K;  1NJI L;  5GAE L;  3I55 K;  1QVF J;  5JVG H;  3G6E K;  3I56 K;  5H1S M;  4WFA H;  1YJN K;  5AN9 E;  1VQ9 K;  4IOC H;  1WHI A;  3OW2 J;  3CCS K;  1VQ8 K;  5JVH H;  5HL7 H;  5GAG L;  1M1K L;  1K9M L;  1VQK K;  1YJW K;  1VQP K;  4IOA H;  4WCE H;  1S72 K;  2ZJQ H;  1K8A L;  1YI2 K;  5MLC M;  3PIO H;  3CMA K;  3CME K;  3CCR K;  1Q7Y L;  1VQM K;  3CC2 K;  1VQ5 K;  1KD1 L;  1JJ2 J;  3CCQ K; 
#chains in the Genus database with same CATH topology
 1K73 L;  3CCE K;  4U67 H;  4IO9 H;  2QA4 K;  1VQ6 K;  3J7Y L;  5DM6 H;  1VQL K;  1YHQ K;  1VQ7 K;  4WFN H;  3CCJ K;  3G4S K;  1VQN K;  2OTJ K;  3DLL H;  1Q81 L;  2ZJP H;  5GAD L;  3CC7 K;  3J7Z K;  3CPW J;  1VQ4 K;  1M90 L;  2OTL K;  2ZJR H;  1KQS J;  3CD6 K;  4WF9 H;  1YIJ K;  1Q86 L;  3G71 K;  3PIP H;  1QVG J;  3CCV K;  3CCM K;  3CCL K;  4WFB H;  5GAH L;  3CXC J;  1KC8 L;  3CF5 H;  1Q82 L;  5DM7 H;  1N8R L;  1W2B J;  3CC4 K;  4V19 O;  1YJ9 K;  1VQO K;  4UY8 K;  1YIT K;  3CCU K;  2QEX K;  1NJI L;  5GAE L;  3I55 K;  1QVF J;  5JVG H;  3G6E K;  3I56 K;  5H1S M;  4WFA H;  1YJN K;  5AN9 E;  1VQ9 K;  4IOC H;  1WHI A;  3OW2 J;  3CCS K;  1VQ8 K;  5JVH H;  5HL7 H;  5GAG L;  1M1K L;  1K9M L;  1VQK K;  1YJW K;  1VQP K;  4IOA H;  4WCE H;  1S72 K;  2ZJQ H;  1K8A L;  1YI2 K;  5MLC M;  3PIO H;  3CMA K;  3CME K;  3CCR K;  1Q7Y L;  1VQM K;  3CC2 K;  1VQ5 K;  1KD1 L;  1JJ2 J;  3CCQ K; 
#chains in the Genus database with same CATH homology
 1K73 L;  3CCE K;  4U67 H;  4IO9 H;  2QA4 K;  1VQ6 K;  3J7Y L;  5DM6 H;  1VQL K;  1YHQ K;  1VQ7 K;  4WFN H;  3CCJ K;  3G4S K;  1VQN K;  2OTJ K;  3DLL H;  1Q81 L;  2ZJP H;  5GAD L;  3CC7 K;  3J7Z K;  3CPW J;  1VQ4 K;  1M90 L;  2OTL K;  2ZJR H;  1KQS J;  3CD6 K;  4WF9 H;  1YIJ K;  1Q86 L;  3G71 K;  3PIP H;  1QVG J;  3CCV K;  3CCM K;  3CCL K;  4WFB H;  5GAH L;  3CXC J;  1KC8 L;  3CF5 H;  1Q82 L;  5DM7 H;  1N8R L;  1W2B J;  3CC4 K;  4V19 O;  1YJ9 K;  1VQO K;  4UY8 K;  1YIT K;  3CCU K;  2QEX K;  1NJI L;  5GAE L;  3I55 K;  1QVF J;  5JVG H;  3G6E K;  3I56 K;  5H1S M;  4WFA H;  1YJN K;  5AN9 E;  1VQ9 K;  4IOC H;  1WHI A;  3OW2 J;  3CCS K;  1VQ8 K;  5JVH H;  5HL7 H;  5GAG L;  1M1K L;  1K9M L;  1VQK K;  1YJW K;  1VQP K;  4IOA H;  4WCE H;  1S72 K;  2ZJQ H;  1K8A L;  1YI2 K;  5MLC M;  3PIO H;  3CMA K;  3CME K;  3CCR K;  1Q7Y L;  1VQM K;  3CC2 K;  1VQ5 K;  1KD1 L;  1JJ2 J;  3CCQ K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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