3SLPA

Crystal structure of lambda exonuclease in complex with a 12 bp symmetric dna duplex
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
226
structure length
226
Chain Sequence
MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKNAWYFANYDPRMKREGLHYVVIERDEKYMASFDEIVPEFIEKMDEALAEIGFVFGEQWR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Enterobacteria phage lambda
molecule keywords Exonuclease
total genus 75
structure length 226
sequence length 226
chains with identical sequence B, C
ec nomenclature ec 3.1.11.3: Exodeoxyribonuclease (lambda-induced).
pdb deposition date 2011-06-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09588 YqaJ YqaJ-like viral recombinase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.320.10 Alpha Beta Alpha-Beta Complex Lambda Exonuclease; Chain A Lambda Exonuclease; Chain A 3slpA00
3SLPA 3K93A 4R5QA 3SYYA 3H4RA 3SZ4A 3U44A 3SZ5A 4CEJA 4CEIA 1W36B 4IC1A 3L0AA 5LD2B 4WUZA 3U4QA 3SM4A 3K70B 1AVQA 4CEHA
chains in the Genus database with same CATH superfamily
3M1VC 5A0YC 1E6YC 3SLPA 1E6VC 3K93A 5A8RC 4R5QA 3SYYA 3U4QA 4CEHA 1HBOC 3M30C 3SQGC 3M2UC 3H4RA 3SZ4A 3U44A 3POTC 3SZ5A 5A8WC 1HBNC 4CEJA 3M32C 4CEIA 1MROC 3M2VC 5A8KC 1W36B 4IC1A 3L0AA 5LD2B 1HBMC 4WUZA 1HBUC 3SM4A 3K70B 1AVQA 3M2RC 5G0RC
chains in the Genus database with same CATH topology
3SLPA 3K93A 4R5QA 3SYYA 3H4RA 3SZ4A 3U44A 3SZ5A 4CEJA 4CEIA 1W36B 4IC1A 3L0AA 5LD2B 4WUZA 3U4QA 3SM4A 3K70B 1AVQA 4CEHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SLP A;  3K93 A;  4R5Q A;  3SYY A;  3H4R A;  3SZ4 A;  3U44 A;  3SZ5 A;  4CEJ A;  4CEI A;  1W36 B;  4IC1 A;  3L0A A;  5LD2 B;  4WUZ A;  3U4Q A;  3SM4 A;  3K70 B;  1AVQ A;  4CEH A; 
#chains in the Genus database with same CATH topology
 3M1V C;  5A0Y C;  1E6Y C;  3SLP A;  1E6V C;  3K93 A;  5A8R C;  4R5Q A;  3SYY A;  3U4Q A;  4CEH A;  1HBO C;  3M30 C;  3SQG C;  3M2U C;  3H4R A;  3SZ4 A;  3U44 A;  3POT C;  3SZ5 A;  5A8W C;  1HBN C;  4CEJ A;  3M32 C;  4CEI A;  1MRO C;  3M2V C;  5A8K C;  1W36 B;  4IC1 A;  3L0A A;  5LD2 B;  1HBM C;  4WUZ A;  1HBU C;  3SM4 A;  3K70 B;  1AVQ A;  3M2R C;  5G0R C; 
#chains in the Genus database with same CATH homology
 3SLP A;  3K93 A;  4R5Q A;  3SYY A;  3H4R A;  3SZ4 A;  3U44 A;  3SZ5 A;  4CEJ A;  4CEI A;  1W36 B;  4IC1 A;  3L0A A;  5LD2 B;  4WUZ A;  3U4Q A;  3SM4 A;  3K70 B;  1AVQ A;  4CEH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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