3SM4A

Crystal structure of the k131a mutant of lambda exonuclease in complex with a 5'-phosphorylated 14-mer/12-mer duplex and magnesium
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
225
structure length
225
Chain Sequence
TPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELACPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKNAWYFANYDPRMKREGLHYVVIERDEKYMASFDEIVPEFIEKMDEALAEIGFVFGEQWR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/dna
molecule keywords Exonuclease
publication title Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
pubmed doi rcsb
source organism Enterobacteria phage lambda
total genus 66
structure length 225
sequence length 225
chains with identical sequence B, C
ec nomenclature ec 3.1.11.3: Exodeoxyribonuclease (lambda-induced).
pdb deposition date 2011-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09588 YqaJ YqaJ-like viral recombinase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.320.10 Alpha Beta Alpha-Beta Complex Lambda Exonuclease; Chain A Lambda Exonuclease; Chain A 3sm4A00
4IC1A 4WUZA 4CEIA 3U4QA 4CEHA 3SZ4A 3K70B 3K93A 3SZ5A 3SYYA 3SLPA 4CEJA 3H4RA 3U44A 1W36B 4R5QA 3L0AA 1AVQA 5LD2B 3SM4A
chains in the Genus database with same CATH superfamily
1E6YC 3M2RC 4IC1A 3M2VC 3POTC 4WUZA 4CEIA 3U4QA 4CEHA 3M2UC 1E6VC 3SZ4A 5G0RC 3K70B 3K93A 3SZ5A 1HBNC 3SYYA 3SLPA 4CEJA 3H4RA 3U44A 1HBUC 1W36B 4R5QA 3SQGC 5A8WC 3L0AA 3M30C 1HBOC 1HBMC 5A8KC 1AVQA 5A8RC 5LD2B 1MROC 3M32C 3SM4A 3M1VC 5A0YC
chains in the Genus database with same CATH topology
4IC1A 4WUZA 4CEIA 3U4QA 4CEHA 3SZ4A 3K70B 3K93A 3SZ5A 3SYYA 3SLPA 4CEJA 3H4RA 3U44A 1W36B 4R5QA 3L0AA 1AVQA 5LD2B 3SM4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IC1 A;  4WUZ A;  4CEI A;  3U4Q A;  4CEH A;  3SZ4 A;  3K70 B;  3K93 A;  3SZ5 A;  3SYY A;  3SLP A;  4CEJ A;  3H4R A;  3U44 A;  1W36 B;  4R5Q A;  3L0A A;  1AVQ A;  5LD2 B;  3SM4 A; 
#chains in the Genus database with same CATH topology
 1E6Y C;  3M2R C;  4IC1 A;  3M2V C;  3POT C;  4WUZ A;  4CEI A;  3U4Q A;  4CEH A;  3M2U C;  1E6V C;  3SZ4 A;  5G0R C;  3K70 B;  3K93 A;  3SZ5 A;  1HBN C;  3SYY A;  3SLP A;  4CEJ A;  3H4R A;  3U44 A;  1HBU C;  1W36 B;  4R5Q A;  3SQG C;  5A8W C;  3L0A A;  3M30 C;  1HBO C;  1HBM C;  5A8K C;  1AVQ A;  5A8R C;  5LD2 B;  1MRO C;  3M32 C;  3SM4 A;  3M1V C;  5A0Y C; 
#chains in the Genus database with same CATH homology
 4IC1 A;  4WUZ A;  4CEI A;  3U4Q A;  4CEH A;  3SZ4 A;  3K70 B;  3K93 A;  3SZ5 A;  3SYY A;  3SLP A;  4CEJ A;  3H4R A;  3U44 A;  1W36 B;  4R5Q A;  3L0A A;  1AVQ A;  5LD2 B;  3SM4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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