3SM4A

Crystal structure of the k131a mutant of lambda exonuclease in complex with a 5'-phosphorylated 14-mer/12-mer duplex and magnesium
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
225
structure length
225
Chain Sequence
TPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELACPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKNAWYFANYDPRMKREGLHYVVIERDEKYMASFDEIVPEFIEKMDEALAEIGFVFGEQWR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Enterobacteria phage lambda
molecule keywords Exonuclease
total genus 66
structure length 225
sequence length 225
chains with identical sequence B, C
ec nomenclature ec 3.1.11.3: Exodeoxyribonuclease (lambda-induced).
pdb deposition date 2011-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09588 YqaJ YqaJ-like viral recombinase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.320.10 Alpha Beta Alpha-Beta Complex Lambda Exonuclease; Chain A Lambda Exonuclease; Chain A 3sm4A00
1AVQA 3L0AA 3K70B 4WUZA 3U44A 3SZ4A 3K93A 3SZ5A 3SM4A 4CEJA 4IC1A 3SLPA 4R5QA 3H4RA 5LD2B 4CEHA 3SYYA 1W36B 3U4QA 4CEIA
chains in the Genus database with same CATH superfamily
1AVQA 3L0AA 3K70B 4WUZA 3M2UC 3U44A 3SZ4A 3K93A 3M32C 3M30C 3SZ5A 3SM4A 4CEJA 3M2RC 4IC1A 5A8WC 3POTC 5A8KC 3SLPA 3M1VC 4R5QA 1HBMC 1E6YC 3H4RA 5LD2B 4CEHA 3SQGC 3SYYA 1HBUC 5A8RC 1W36B 1HBNC 3U4QA 4CEIA 5G0RC 1HBOC 1E6VC 1MROC 5A0YC 3M2VC
chains in the Genus database with same CATH topology
1AVQA 3L0AA 3K70B 4WUZA 3U44A 3SZ4A 3K93A 3SZ5A 3SM4A 4CEJA 4IC1A 3SLPA 4R5QA 3H4RA 5LD2B 4CEHA 3SYYA 1W36B 3U4QA 4CEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AVQ A;  3L0A A;  3K70 B;  4WUZ A;  3U44 A;  3SZ4 A;  3K93 A;  3SZ5 A;  3SM4 A;  4CEJ A;  4IC1 A;  3SLP A;  4R5Q A;  3H4R A;  5LD2 B;  4CEH A;  3SYY A;  1W36 B;  3U4Q A;  4CEI A; 
#chains in the Genus database with same CATH topology
 1AVQ A;  3L0A A;  3K70 B;  4WUZ A;  3M2U C;  3U44 A;  3SZ4 A;  3K93 A;  3M32 C;  3M30 C;  3SZ5 A;  3SM4 A;  4CEJ A;  3M2R C;  4IC1 A;  5A8W C;  3POT C;  5A8K C;  3SLP A;  3M1V C;  4R5Q A;  1HBM C;  1E6Y C;  3H4R A;  5LD2 B;  4CEH A;  3SQG C;  3SYY A;  1HBU C;  5A8R C;  1W36 B;  1HBN C;  3U4Q A;  4CEI A;  5G0R C;  1HBO C;  1E6V C;  1MRO C;  5A0Y C;  3M2V C; 
#chains in the Genus database with same CATH homology
 1AVQ A;  3L0A A;  3K70 B;  4WUZ A;  3U44 A;  3SZ4 A;  3K93 A;  3SZ5 A;  3SM4 A;  4CEJ A;  4IC1 A;  3SLP A;  4R5Q A;  3H4R A;  5LD2 B;  4CEH A;  3SYY A;  1W36 B;  3U4Q A;  4CEI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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