3SM4A

Crystal structure of the k131a mutant of lambda exonuclease in complex with a 5'-phosphorylated 14-mer/12-mer duplex and magnesium
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
225
structure length
225
Chain Sequence
TPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELACPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKNAWYFANYDPRMKREGLHYVVIERDEKYMASFDEIVPEFIEKMDEALAEIGFVFGEQWR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Enterobacteria phage lambda
molecule keywords Exonuclease
total genus 66
structure length 225
sequence length 225
chains with identical sequence B, C
ec nomenclature ec 3.1.11.3: Exodeoxyribonuclease (lambda-induced).
pdb deposition date 2011-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09588 YqaJ YqaJ-like viral recombinase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.320.10 Alpha Beta Alpha-Beta Complex Lambda Exonuclease; Chain A Lambda Exonuclease; Chain A 3sm4A00
5LD2B 3U44A 4CEHA 4CEIA 3K70B 4WUZA 3U4QA 1AVQA 4CEJA 3SZ4A 3SZ5A 4IC1A 3H4RA 3K93A 4R5QA 3SYYA 3L0AA 3SLPA 3SM4A 1W36B
chains in the Genus database with same CATH superfamily
5LD2B 3U44A 4CEHA 4CEIA 1HBMC 3POTC 3K70B 5A0YC 3M30C 1HBUC 4WUZA 3U4QA 1AVQA 4CEJA 3M2UC 3SQGC 3SZ4A 1HBNC 1MROC 5A8WC 3M1VC 3SZ5A 5G0RC 4IC1A 3H4RA 3K93A 4R5QA 5A8KC 3SYYA 1E6VC 3L0AA 3M2VC 5A8RC 3SLPA 1E6YC 3M2RC 1HBOC 3SM4A 1W36B 3M32C
chains in the Genus database with same CATH topology
5LD2B 3U44A 4CEHA 4CEIA 3K70B 4WUZA 3U4QA 1AVQA 4CEJA 3SZ4A 3SZ5A 4IC1A 3H4RA 3K93A 4R5QA 3SYYA 3L0AA 3SLPA 3SM4A 1W36B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5LD2 B;  3U44 A;  4CEH A;  4CEI A;  3K70 B;  4WUZ A;  3U4Q A;  1AVQ A;  4CEJ A;  3SZ4 A;  3SZ5 A;  4IC1 A;  3H4R A;  3K93 A;  4R5Q A;  3SYY A;  3L0A A;  3SLP A;  3SM4 A;  1W36 B; 
#chains in the Genus database with same CATH topology
 5LD2 B;  3U44 A;  4CEH A;  4CEI A;  1HBM C;  3POT C;  3K70 B;  5A0Y C;  3M30 C;  1HBU C;  4WUZ A;  3U4Q A;  1AVQ A;  4CEJ A;  3M2U C;  3SQG C;  3SZ4 A;  1HBN C;  1MRO C;  5A8W C;  3M1V C;  3SZ5 A;  5G0R C;  4IC1 A;  3H4R A;  3K93 A;  4R5Q A;  5A8K C;  3SYY A;  1E6V C;  3L0A A;  3M2V C;  5A8R C;  3SLP A;  1E6Y C;  3M2R C;  1HBO C;  3SM4 A;  1W36 B;  3M32 C; 
#chains in the Genus database with same CATH homology
 5LD2 B;  3U44 A;  4CEH A;  4CEI A;  3K70 B;  4WUZ A;  3U4Q A;  1AVQ A;  4CEJ A;  3SZ4 A;  3SZ5 A;  4IC1 A;  3H4R A;  3K93 A;  4R5Q A;  3SYY A;  3L0A A;  3SLP A;  3SM4 A;  1W36 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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