3TQ6A

Crystal structure of human mitochondrial transcription factor a, tfam or mttfa, bound to the light strand promoter lsp
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
194
structure length
194
Chain Sequence
SVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRTIKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords Transcription factor A, mitochondrial
total genus 76
structure length 194
sequence length 194
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00505 HMG_box HMG (high mobility group) box
A PF09011 HMG_box_2 HMG-box domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 3tq6A02
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 3tq6A01
1HRZA 1WZ6A 2RTUA 1J47A 1E7JA 3F27D 3TMMA 2YRQA 1WGFA 1GT0D 2CO9A 2HDZA 2CTOA 1K99A 1J3CA 4S2QD 1AABA 1I11A 1L8ZA 1NHNA 1V64A 2YULA 2LE4A 4QR9A 1CKTA 3U2BC 1QRVA 1HMFA 1HMAA 1WXLA 3FGHA 2LEFA 2E6OA 2CRJA 2YUKA 4EUWA 1J46A 4Y60C 4NODA 2LY4A 1J3XA 1L8YA 3TQ6A 1HRYA 1CG7A 4A3NA 1J5NA 2GZKA 1J3DA 1HSNA 1NHMA 1LWMA 1V63A 2EQZA 2YQIA 2CS1A 2LHJA 2D7LA 4NNUA 1HSMA 3NM9A 1O4XB 1HMEA
chains in the Genus database with same CATH superfamily
1HRZA 1WZ6A 2RTUA 1J47A 1E7JA 3F27D 3TMMA 2YRQA 1WGFA 1GT0D 2CO9A 2HDZA 2CTOA 3ABOB 1K99A 1J3CA 4S2QD 1AABA 3AO0B 1I11A 1L8ZA 3ANYB 1NHNA 1V64A 2YULA 2LE4A 4QR9A 1CKTA 2VSFA 3U2BC 1QRVA 1HMFA 1HMAA 1WXLA 3FGHA 2LEFA 2E6OA 2CRJA 2YUKA 4EUWA 1J46A 4Y60C 4NODA 2LY4A 1J3XA 3ABRB 1L8YA 3TQ6A 1HRYA 1CG7A 4A3NA 1J5NA 5H8WA 2GZKA 1J3DA 1NHMA 3ABSB 1HSNA 1LWMA 1V63A 2EQZA 2YQIA 2CS1A 2LHJA 4KQEA 2D7LA 4A15A 4NNUA 1HSMA 3NM9A 1O4XB 1HMEA
chains in the Genus database with same CATH topology
1HRZA 1WZ6A 2RTUA 1J47A 1E7JA 3F27D 3TMMA 2YRQA 1WGFA 1GT0D 2CO9A 2HDZA 2CTOA 1K99A 1J3CA 4S2QD 1AABA 1I11A 1L8ZA 1NHNA 1V64A 2YULA 2LE4A 4QR9A 1CKTA 3U2BC 1QRVA 1HMFA 1HMAA 1WXLA 3FGHA 2LEFA 2E6OA 2CRJA 2YUKA 4EUWA 1J46A 4Y60C 4NODA 2LY4A 1J3XA 1L8YA 3TQ6A 1HRYA 1CG7A 4A3NA 1J5NA 2GZKA 1J3DA 1HSNA 1NHMA 1LWMA 1V63A 2EQZA 2YQIA 2CS1A 2LHJA 2D7LA 4NNUA 1HSMA 3NM9A 1O4XB 1HMEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HRZ A;  1WZ6 A;  2RTU A;  1J47 A;  1E7J A;  3F27 D;  3TMM A;  2YRQ A;  1WGF A;  1GT0 D;  2CO9 A;  2HDZ A;  2CTO A;  1K99 A;  1J3C A;  4S2Q D;  1AAB A;  1I11 A;  1L8Z A;  1NHN A;  1V64 A;  2YUL A;  2LE4 A;  4QR9 A;  1CKT A;  3U2B C;  1QRV A;  1HMF A;  1HMA A;  1WXL A;  3FGH A;  2LEF A;  2E6O A;  2CRJ A;  2YUK A;  4EUW A;  1J46 A;  4Y60 C;  4NOD A;  2LY4 A;  1J3X A;  1L8Y A;  3TQ6 A;  1HRY A;  1CG7 A;  4A3N A;  1J5N A;  2GZK A;  1J3D A;  1HSN A;  1NHM A;  1LWM A;  1V63 A;  2EQZ A;  2YQI A;  2CS1 A;  2LHJ A;  2D7L A;  4NNU A;  1HSM A;  3NM9 A;  1O4X B;  1HME A; 
#chains in the Genus database with same CATH topology
 1HRZ A;  1WZ6 A;  2RTU A;  1J47 A;  1E7J A;  3F27 D;  3TMM A;  2YRQ A;  1WGF A;  1GT0 D;  2CO9 A;  2HDZ A;  2CTO A;  3ABO B;  1K99 A;  1J3C A;  4S2Q D;  1AAB A;  3AO0 B;  1I11 A;  1L8Z A;  3ANY B;  1NHN A;  1V64 A;  2YUL A;  2LE4 A;  4QR9 A;  1CKT A;  2VSF A;  3U2B C;  1QRV A;  1HMF A;  1HMA A;  1WXL A;  3FGH A;  2LEF A;  2E6O A;  2CRJ A;  2YUK A;  4EUW A;  1J46 A;  4Y60 C;  4NOD A;  2LY4 A;  1J3X A;  3ABR B;  1L8Y A;  3TQ6 A;  1HRY A;  1CG7 A;  4A3N A;  1J5N A;  5H8W A;  2GZK A;  1J3D A;  1NHM A;  3ABS B;  1HSN A;  1LWM A;  1V63 A;  2EQZ A;  2YQI A;  2CS1 A;  2LHJ A;  4KQE A;  2D7L A;  4A15 A;  4NNU A;  1HSM A;  3NM9 A;  1O4X B;  1HME A; 
#chains in the Genus database with same CATH homology
 1HRZ A;  1WZ6 A;  2RTU A;  1J47 A;  1E7J A;  3F27 D;  3TMM A;  2YRQ A;  1WGF A;  1GT0 D;  2CO9 A;  2HDZ A;  2CTO A;  1K99 A;  1J3C A;  4S2Q D;  1AAB A;  1I11 A;  1L8Z A;  1NHN A;  1V64 A;  2YUL A;  2LE4 A;  4QR9 A;  1CKT A;  3U2B C;  1QRV A;  1HMF A;  1HMA A;  1WXL A;  3FGH A;  2LEF A;  2E6O A;  2CRJ A;  2YUK A;  4EUW A;  1J46 A;  4Y60 C;  4NOD A;  2LY4 A;  1J3X A;  1L8Y A;  3TQ6 A;  1HRY A;  1CG7 A;  4A3N A;  1J5N A;  2GZK A;  1J3D A;  1HSN A;  1NHM A;  1LWM A;  1V63 A;  2EQZ A;  2YQI A;  2CS1 A;  2LHJ A;  2D7L A;  4NNU A;  1HSM A;  3NM9 A;  1O4X B;  1HME A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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