3U2BC

Structure of the sox4 hmg domain bound to dna
Total Genus 22
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
76
structure length
76
Chain Sequence
GHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIQEAERLRLKHMADYPDYKYRPRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism for positional interdependence in DNA recognition
pubmed doi rcsb
molecule tags Transcription/dna
source organism Mus musculus
molecule keywords DNA (5'-D(*GP*TP*CP*TP*CP*TP*AP*TP*TP*GP*TP*CP*CP*TP*GP*G)-3
total genus 22
structure length 76
sequence length 76
ec nomenclature
pdb deposition date 2011-10-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00505 HMG_box HMG (high mobility group) box
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 3u2bC00
1NHMA 1HRZA 1AABA 2RTUA 3TMMA 1HSMA 1WXLA 2CTOA 2YRQA 1I11A 3F27D 2GZKA 1J3CA 2LHJA 1L8ZA 1HMFA 2CO9A 2LEFA 1V63A 4S2QD 1HMAA 1NHNA 4A3NA 1HMEA 1K99A 3U2BC 1LWMA 1O4XB 4NNUA 2CS1A 4QR9A 2YQIA 4Y60C 1J46A 2EQZA 1HRYA 2LY4A 1J5NA 2YULA 1WGFA 1CG7A 2CRJA 2HDZA 3NM9A 1L8YA 4EUWA 1GT0D 1J47A 3FGHA 1J3XA 1QRVA 1HSNA 2D7LA 2YUKA 1E7JA 1WZ6A 4NODA 2E6OA 1V64A 2LE4A 1CKTA 3TQ6A 1J3DA
chains in the Genus database with same CATH superfamily
1NHMA 1HRZA 1AABA 3ANYB 2RTUA 3TMMA 1HSMA 5H8WA 1WXLA 2CTOA 2YRQA 1I11A 3F27D 2GZKA 4A15A 2LHJA 1J3CA 1L8ZA 1HMFA 2CO9A 2LEFA 1V63A 3ABOB 4S2QD 1HMAA 1NHNA 4KQEA 3ABSB 4A3NA 1HMEA 1K99A 3U2BC 1LWMA 1O4XB 4NNUA 2CS1A 4QR9A 2YQIA 4Y60C 1J46A 2EQZA 1HRYA 2LY4A 1J5NA 2YULA 1WGFA 1CG7A 2CRJA 2HDZA 3AO0B 1L8YA 3NM9A 4EUWA 1GT0D 3ABRB 3FGHA 1J47A 2VSFA 1J3XA 1QRVA 1HSNA 2D7LA 2YUKA 1E7JA 1WZ6A 4NODA 2E6OA 1V64A 2LE4A 1CKTA 3TQ6A 1J3DA
chains in the Genus database with same CATH topology
1NHMA 1HRZA 1AABA 2RTUA 3TMMA 1HSMA 1WXLA 2CTOA 2YRQA 1I11A 3F27D 2GZKA 1J3CA 2LHJA 1L8ZA 1HMFA 2CO9A 2LEFA 1V63A 4S2QD 1HMAA 1NHNA 4A3NA 1HMEA 1K99A 3U2BC 1LWMA 1O4XB 4NNUA 2CS1A 4QR9A 2YQIA 4Y60C 1J46A 2EQZA 1HRYA 2LY4A 1J5NA 2YULA 1WGFA 1CG7A 2CRJA 2HDZA 3NM9A 1L8YA 4EUWA 1GT0D 1J47A 3FGHA 1J3XA 1QRVA 1HSNA 2D7LA 2YUKA 1E7JA 1WZ6A 4NODA 2E6OA 1V64A 2LE4A 1CKTA 3TQ6A 1J3DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NHM A;  1HRZ A;  1AAB A;  2RTU A;  3TMM A;  1HSM A;  1WXL A;  2CTO A;  2YRQ A;  1I11 A;  3F27 D;  2GZK A;  1J3C A;  2LHJ A;  1L8Z A;  1HMF A;  2CO9 A;  2LEF A;  1V63 A;  4S2Q D;  1HMA A;  1NHN A;  4A3N A;  1HME A;  1K99 A;  3U2B C;  1LWM A;  1O4X B;  4NNU A;  2CS1 A;  4QR9 A;  2YQI A;  4Y60 C;  1J46 A;  2EQZ A;  1HRY A;  2LY4 A;  1J5N A;  2YUL A;  1WGF A;  1CG7 A;  2CRJ A;  2HDZ A;  3NM9 A;  1L8Y A;  4EUW A;  1GT0 D;  1J47 A;  3FGH A;  1J3X A;  1QRV A;  1HSN A;  2D7L A;  2YUK A;  1E7J A;  1WZ6 A;  4NOD A;  2E6O A;  1V64 A;  2LE4 A;  1CKT A;  3TQ6 A;  1J3D A; 
#chains in the Genus database with same CATH topology
 1NHM A;  1HRZ A;  1AAB A;  3ANY B;  2RTU A;  3TMM A;  1HSM A;  5H8W A;  1WXL A;  2CTO A;  2YRQ A;  1I11 A;  3F27 D;  2GZK A;  4A15 A;  2LHJ A;  1J3C A;  1L8Z A;  1HMF A;  2CO9 A;  2LEF A;  1V63 A;  3ABO B;  4S2Q D;  1HMA A;  1NHN A;  4KQE A;  3ABS B;  4A3N A;  1HME A;  1K99 A;  3U2B C;  1LWM A;  1O4X B;  4NNU A;  2CS1 A;  4QR9 A;  2YQI A;  4Y60 C;  1J46 A;  2EQZ A;  1HRY A;  2LY4 A;  1J5N A;  2YUL A;  1WGF A;  1CG7 A;  2CRJ A;  2HDZ A;  3AO0 B;  1L8Y A;  3NM9 A;  4EUW A;  1GT0 D;  3ABR B;  3FGH A;  1J47 A;  2VSF A;  1J3X A;  1QRV A;  1HSN A;  2D7L A;  2YUK A;  1E7J A;  1WZ6 A;  4NOD A;  2E6O A;  1V64 A;  2LE4 A;  1CKT A;  3TQ6 A;  1J3D A; 
#chains in the Genus database with same CATH homology
 1NHM A;  1HRZ A;  1AAB A;  2RTU A;  3TMM A;  1HSM A;  1WXL A;  2CTO A;  2YRQ A;  1I11 A;  3F27 D;  2GZK A;  1J3C A;  2LHJ A;  1L8Z A;  1HMF A;  2CO9 A;  2LEF A;  1V63 A;  4S2Q D;  1HMA A;  1NHN A;  4A3N A;  1HME A;  1K99 A;  3U2B C;  1LWM A;  1O4X B;  4NNU A;  2CS1 A;  4QR9 A;  2YQI A;  4Y60 C;  1J46 A;  2EQZ A;  1HRY A;  2LY4 A;  1J5N A;  2YUL A;  1WGF A;  1CG7 A;  2CRJ A;  2HDZ A;  3NM9 A;  1L8Y A;  4EUW A;  1GT0 D;  1J47 A;  3FGH A;  1J3X A;  1QRV A;  1HSN A;  2D7L A;  2YUK A;  1E7J A;  1WZ6 A;  4NOD A;  2E6O A;  1V64 A;  2LE4 A;  1CKT A;  3TQ6 A;  1J3D A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...