3W6RA

Crystal structure of the gap domain of human mgcracgap
Total Genus 71
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
200
structure length
200
Chain Sequence
MEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWSQFMMVE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of GTPase-activating domain from human MgcRacGAP.
pubmed doi rcsb
molecule keywords Rac GTPase-activating protein 1
molecule tags Signaling protein
source organism Homo sapiens
total genus 71
structure length 200
sequence length 200
ec nomenclature
pdb deposition date 2013-02-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 3w6rA00
3FK2A 3QISA 3EAPA 1F7CA 1OW3A 5IRCA 5C5SA 3WPSA 5C2JA 1RGPA 2XS6A 3IUGA 3MSXB 1PBWA 3KUQA 3WPQA 2OSAA 2EE5A 2OVJA 1TX4A 5JD0A 1AM4A 3BYIA 1XA6A 2EE4A 1GRNB 5HPYA 2QV2A 5JCPA 2MBGA 3CXLA 3W6RA 2NGRB
chains in the Genus database with same CATH superfamily
3FK2A 3QISA 3EAPA 1F7CA 1OW3A 5IRCA 5C5SA 3WPSA 5C2JA 1RGPA 2XS6A 3IUGA 3MSXB 1PBWA 3KUQA 3WPQA 2OSAA 2EE5A 2OVJA 1TX4A 5JD0A 1AM4A 3BYIA 1XA6A 2EE4A 1GRNB 5HPYA 2QV2A 5JCPA 2MBGA 3CXLA 3W6RA 2NGRB
chains in the Genus database with same CATH topology
3FK2A 3QISA 3EAPA 1F7CA 1OW3A 5IRCA 5C5SA 3WPSA 5C2JA 1RGPA 2XS6A 3IUGA 3MSXB 1PBWA 3KUQA 3WPQA 2OSAA 2EE5A 2OVJA 1TX4A 5JD0A 1AM4A 3BYIA 1XA6A 2EE4A 1GRNB 5HPYA 2QV2A 5JCPA 2MBGA 3CXLA 3W6RA 2NGRB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FK2 A;  3QIS A;  3EAP A;  1F7C A;  1OW3 A;  5IRC A;  5C5S A;  3WPS A;  5C2J A;  1RGP A;  2XS6 A;  3IUG A;  3MSX B;  1PBW A;  3KUQ A;  3WPQ A;  2OSA A;  2EE5 A;  2OVJ A;  1TX4 A;  5JD0 A;  1AM4 A;  3BYI A;  1XA6 A;  2EE4 A;  1GRN B;  5HPY A;  2QV2 A;  5JCP A;  2MBG A;  3CXL A;  3W6R A;  2NGR B; 
#chains in the Genus database with same CATH topology
 3FK2 A;  3QIS A;  3EAP A;  1F7C A;  1OW3 A;  5IRC A;  5C5S A;  3WPS A;  5C2J A;  1RGP A;  2XS6 A;  3IUG A;  3MSX B;  1PBW A;  3KUQ A;  3WPQ A;  2OSA A;  2EE5 A;  2OVJ A;  1TX4 A;  5JD0 A;  1AM4 A;  3BYI A;  1XA6 A;  2EE4 A;  1GRN B;  5HPY A;  2QV2 A;  5JCP A;  2MBG A;  3CXL A;  3W6R A;  2NGR B; 
#chains in the Genus database with same CATH homology
 3FK2 A;  3QIS A;  3EAP A;  1F7C A;  1OW3 A;  5IRC A;  5C5S A;  3WPS A;  5C2J A;  1RGP A;  2XS6 A;  3IUG A;  3MSX B;  1PBW A;  3KUQ A;  3WPQ A;  2OSA A;  2EE5 A;  2OVJ A;  1TX4 A;  5JD0 A;  1AM4 A;  3BYI A;  1XA6 A;  2EE4 A;  1GRN B;  5HPY A;  2QV2 A;  5JCP A;  2MBG A;  3CXL A;  3W6R A;  2NGR B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...