3WPQA

Crystal structure of the gap domain of mgcracgap(s387a)
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
200
structure length
200
Chain Sequence
IGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRIAGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMSQDIKRQPKVVERLLSLPLEYWSQFMMV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title crystal structure of the GAP domain of MgcRacGAP
rcsb
molecule keywords Rac GTPase-activating protein 1
molecule tags Signaling protein
source organism Homo sapiens
total genus 69
structure length 200
sequence length 200
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 3wpqA00
5HPYA 3W6RA 3QISA 2OSAA 1OW3A 3KUQA 2MBGA 3WPQA 2NGRB 1GRNB 5JD0A 3MSXB 3WPSA 5C2JA 2QV2A 2OVJA 5JCPA 1PBWA 1AM4A 3IUGA 1XA6A 1F7CA 3CXLA 2EE5A 5C5SA 3BYIA 2EE4A 3FK2A 5IRCA 1TX4A 3EAPA 2XS6A 1RGPA
chains in the Genus database with same CATH superfamily
5HPYA 3W6RA 3QISA 2OSAA 1OW3A 3KUQA 2MBGA 3WPQA 2NGRB 1GRNB 5JD0A 3MSXB 3WPSA 5C2JA 2QV2A 2OVJA 5JCPA 1PBWA 1AM4A 3IUGA 1XA6A 1F7CA 3CXLA 2EE5A 5C5SA 3BYIA 2EE4A 3FK2A 5IRCA 1TX4A 3EAPA 2XS6A 1RGPA
chains in the Genus database with same CATH topology
5HPYA 3W6RA 3QISA 2OSAA 1OW3A 3KUQA 2MBGA 3WPQA 2NGRB 1GRNB 5JD0A 3MSXB 3WPSA 5C2JA 2QV2A 2OVJA 5JCPA 1PBWA 1AM4A 3IUGA 1XA6A 1F7CA 3CXLA 2EE5A 5C5SA 3BYIA 2EE4A 3FK2A 5IRCA 1TX4A 3EAPA 2XS6A 1RGPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HPY A;  3W6R A;  3QIS A;  2OSA A;  1OW3 A;  3KUQ A;  2MBG A;  3WPQ A;  2NGR B;  1GRN B;  5JD0 A;  3MSX B;  3WPS A;  5C2J A;  2QV2 A;  2OVJ A;  5JCP A;  1PBW A;  1AM4 A;  3IUG A;  1XA6 A;  1F7C A;  3CXL A;  2EE5 A;  5C5S A;  3BYI A;  2EE4 A;  3FK2 A;  5IRC A;  1TX4 A;  3EAP A;  2XS6 A;  1RGP A; 
#chains in the Genus database with same CATH topology
 5HPY A;  3W6R A;  3QIS A;  2OSA A;  1OW3 A;  3KUQ A;  2MBG A;  3WPQ A;  2NGR B;  1GRN B;  5JD0 A;  3MSX B;  3WPS A;  5C2J A;  2QV2 A;  2OVJ A;  5JCP A;  1PBW A;  1AM4 A;  3IUG A;  1XA6 A;  1F7C A;  3CXL A;  2EE5 A;  5C5S A;  3BYI A;  2EE4 A;  3FK2 A;  5IRC A;  1TX4 A;  3EAP A;  2XS6 A;  1RGP A; 
#chains in the Genus database with same CATH homology
 5HPY A;  3W6R A;  3QIS A;  2OSA A;  1OW3 A;  3KUQ A;  2MBG A;  3WPQ A;  2NGR B;  1GRN B;  5JD0 A;  3MSX B;  3WPS A;  5C2J A;  2QV2 A;  2OVJ A;  5JCP A;  1PBW A;  1AM4 A;  3IUG A;  1XA6 A;  1F7C A;  3CXL A;  2EE5 A;  5C5S A;  3BYI A;  2EE4 A;  3FK2 A;  5IRC A;  1TX4 A;  3EAP A;  2XS6 A;  1RGP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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