3WPSA

Crystal structure of the gap domain of mgcracgap(s387d)
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
201
structure length
201
Chain Sequence
IGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRIDGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMSQDIKRQPKVVERLLSLPLEYWSQFMMVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title crystal structure of the GAP domain of MgcRacGAP
rcsb
molecule keywords Rac GTPase-activating protein 1
molecule tags Signaling protein
source organism Homo sapiens
total genus 60
structure length 201
sequence length 201
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 3wpsA00
2EE5A 3WPQA 3IUGA 3QISA 1RGPA 5IRCA 2QV2A 2OSAA 1AM4A 5C2JA 1XA6A 3EAPA 3MSXB 1TX4A 2NGRB 1F7CA 3BYIA 5HPYA 2XS6A 3WPSA 2OVJA 3CXLA 3W6RA 2EE4A 1PBWA 5JCPA 3KUQA 5C5SA 2MBGA 1OW3A 3FK2A 5JD0A 1GRNB
chains in the Genus database with same CATH superfamily
2EE5A 3WPQA 3IUGA 3QISA 1RGPA 5IRCA 2QV2A 2OSAA 1AM4A 5C2JA 1XA6A 3EAPA 3MSXB 1TX4A 2NGRB 1F7CA 3BYIA 5HPYA 2XS6A 3WPSA 2OVJA 3CXLA 3W6RA 2EE4A 1PBWA 5JCPA 3KUQA 5C5SA 2MBGA 1OW3A 3FK2A 5JD0A 1GRNB
chains in the Genus database with same CATH topology
2EE5A 3WPQA 3IUGA 3QISA 1RGPA 5IRCA 2QV2A 2OSAA 1AM4A 5C2JA 1XA6A 3EAPA 3MSXB 1TX4A 2NGRB 1F7CA 3BYIA 5HPYA 2XS6A 3WPSA 2OVJA 3CXLA 3W6RA 2EE4A 1PBWA 5JCPA 3KUQA 5C5SA 2MBGA 1OW3A 3FK2A 5JD0A 1GRNB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EE5 A;  3WPQ A;  3IUG A;  3QIS A;  1RGP A;  5IRC A;  2QV2 A;  2OSA A;  1AM4 A;  5C2J A;  1XA6 A;  3EAP A;  3MSX B;  1TX4 A;  2NGR B;  1F7C A;  3BYI A;  5HPY A;  2XS6 A;  3WPS A;  2OVJ A;  3CXL A;  3W6R A;  2EE4 A;  1PBW A;  5JCP A;  3KUQ A;  5C5S A;  2MBG A;  1OW3 A;  3FK2 A;  5JD0 A;  1GRN B; 
#chains in the Genus database with same CATH topology
 2EE5 A;  3WPQ A;  3IUG A;  3QIS A;  1RGP A;  5IRC A;  2QV2 A;  2OSA A;  1AM4 A;  5C2J A;  1XA6 A;  3EAP A;  3MSX B;  1TX4 A;  2NGR B;  1F7C A;  3BYI A;  5HPY A;  2XS6 A;  3WPS A;  2OVJ A;  3CXL A;  3W6R A;  2EE4 A;  1PBW A;  5JCP A;  3KUQ A;  5C5S A;  2MBG A;  1OW3 A;  3FK2 A;  5JD0 A;  1GRN B; 
#chains in the Genus database with same CATH homology
 2EE5 A;  3WPQ A;  3IUG A;  3QIS A;  1RGP A;  5IRC A;  2QV2 A;  2OSA A;  1AM4 A;  5C2J A;  1XA6 A;  3EAP A;  3MSX B;  1TX4 A;  2NGR B;  1F7C A;  3BYI A;  5HPY A;  2XS6 A;  3WPS A;  2OVJ A;  3CXL A;  3W6R A;  2EE4 A;  1PBW A;  5JCP A;  3KUQ A;  5C5S A;  2MBG A;  1OW3 A;  3FK2 A;  5JD0 A;  1GRN B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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