3WPS | Genus

Total Genus 60

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	60
sequence length	201
structure length	201
Chain Sequence	IGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRIDGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMSQDIKRQPKVVERLLSLPLEYWSQFMMVE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 201 atoms

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201 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

publication title	crystal structure of the GAP domain of MgcRacGAP rcsb
molecule keywords	Rac GTPase-activating protein 1
molecule tags	Signaling protein
source organism	Homo sapiens
total genus	60
structure length	201
sequence length	201
chains with identical sequence	B
ec nomenclature
pdb deposition date	2014-01-15

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00620	RhoGAP	RhoGAP domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.555.10	Mainly Alpha	Orthogonal Bundle	Phosphatidylinositol 3-kinase; Chain A	Rho GTPase activation protein	3wpsA00

5C2JA 3KUQA 2NGRB 2OSAA 3MSXB 2MBGA 1PBWA 5JD0A 2QV2A 2XS6A 5JCPA 3QISA 5IRCA 2EE5A 1GRNB 3IUGA 3WPQA 2EE4A 1F7CA 3W6RA 3FK2A 1AM4A 3CXLA 5HPYA 3EAPA 1TX4A 3BYIA 2OVJA 1OW3A 5C5SA 3WPSA 1XA6A 1RGPA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5C2J A;  3KUQ A;  2NGR B;  2OSA A;  3MSX B;  2MBG A;  1PBW A;  5JD0 A;  2QV2 A;  2XS6 A;  5JCP A;  3QIS A;  5IRC A;  2EE5 A;  1GRN B;  3IUG A;  3WPQ A;  2EE4 A;  1F7C A;  3W6R A;  3FK2 A;  1AM4 A;  3CXL A;  5HPY A;  3EAP A;  1TX4 A;  3BYI A;  2OVJ A;  1OW3 A;  5C5S A;  3WPS A;  1XA6 A;  1RGP A; 
#chains in the Genus database with same CATH topology
 5C2J A;  3KUQ A;  2NGR B;  2OSA A;  3MSX B;  2MBG A;  1PBW A;  5JD0 A;  2QV2 A;  2XS6 A;  5JCP A;  3QIS A;  5IRC A;  2EE5 A;  1GRN B;  3IUG A;  3WPQ A;  2EE4 A;  1F7C A;  3W6R A;  3FK2 A;  1AM4 A;  3CXL A;  5HPY A;  3EAP A;  1TX4 A;  3BYI A;  2OVJ A;  1OW3 A;  5C5S A;  3WPS A;  1XA6 A;  1RGP A; 
#chains in the Genus database with same CATH homology
 5C2J A;  3KUQ A;  2NGR B;  2OSA A;  3MSX B;  2MBG A;  1PBW A;  5JD0 A;  2QV2 A;  2XS6 A;  5JCP A;  3QIS A;  5IRC A;  2EE5 A;  1GRN B;  3IUG A;  3WPQ A;  2EE4 A;  1F7C A;  3W6R A;  3FK2 A;  1AM4 A;  3CXL A;  5HPY A;  3EAP A;  1TX4 A;  3BYI A;  2OVJ A;  1OW3 A;  5C5S A;  3WPS A;  1XA6 A;  1RGP A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3WPSA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations