3CC7K

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2487u
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
132
structure length
132
Chain Sequence
MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 29
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 3cc7K00
3G4SK 1VQOK 1VQMK 2OTLK 1QVFJ 1VQPK 1W2BJ 1N8RL 4WFAH 3CCQK 1VQ4K 5MLCM 5GAHL 5JVGH 3CXCJ 5JVHH 5H1SM 1VQ9K 1VQKK 1VQ5K 4U67H 3CCMK 3CC4K 2QEXK 4UY8K 1K9ML 2ZJQH 3PIOH 4IOAH 1NJIL 1K8AL 1KC8L 4V19O 3CF5H 1VQ6K 1YJNK 3CC2K 1YJWK 3CC7K 4WFNH 1Q81L 4IO9H 1VQLK 3J7YL 3G71K 4WFBH 3CCSK 1Q86L 5HL7H 1VQ7K 1QVGJ 5DM6H 5DM7H 3CCRK 3PIPH 1Q7YL 3CPWJ 3J7ZK 3CMAK 1WHIA 3DLLH 1M1KL 4IOCH 3CCEK 1KD1L 5AN9E 1YITK 1K73L 3I56K 3CD6K 2ZJRH 1S72K 1YJ9K 3CCUK 3CCVK 5GAEL 3CCJK 5GAGL 3CMEK 2QA4K 3I55K 1M90L 2OTJK 1KQSJ 5GADL 3G6EK 1YIJK 4WCEH 4WF9H 2ZJPH 1VQ8K 3OW2J 1VQNK 1Q82L 3CCLK 1YI2K 1YHQK 1JJ2J
chains in the Genus database with same CATH superfamily
3G4SK 1VQOK 1VQMK 2OTLK 1QVFJ 1VQPK 1W2BJ 1N8RL 4WFAH 3CCQK 1VQ4K 5MLCM 5GAHL 5JVGH 3CXCJ 5JVHH 5H1SM 1VQ9K 1VQKK 1VQ5K 4U67H 3CCMK 3CC4K 2QEXK 4UY8K 1K9ML 2ZJQH 3PIOH 4IOAH 1NJIL 1K8AL 1KC8L 4V19O 3CF5H 1VQ6K 1YJNK 3CC2K 1YJWK 3CC7K 4WFNH 1Q81L 4IO9H 1VQLK 3J7YL 3G71K 4WFBH 3CCSK 1Q86L 5HL7H 1VQ7K 1QVGJ 5DM6H 5DM7H 3CCRK 3PIPH 1Q7YL 3CPWJ 3J7ZK 3CMAK 1WHIA 3DLLH 1M1KL 4IOCH 3CCEK 1KD1L 5AN9E 1YITK 1K73L 3I56K 3CD6K 2ZJRH 1S72K 1YJ9K 3CCUK 3CCVK 5GAEL 3CCJK 5GAGL 3CMEK 2QA4K 3I55K 1M90L 2OTJK 1KQSJ 5GADL 3G6EK 1YIJK 4WCEH 4WF9H 2ZJPH 1VQ8K 3OW2J 1VQNK 1Q82L 3CCLK 1YI2K 1YHQK 1JJ2J
chains in the Genus database with same CATH topology
3G4SK 1VQOK 1VQMK 2OTLK 1QVFJ 1VQPK 1W2BJ 1N8RL 4WFAH 3CCQK 1VQ4K 5MLCM 5GAHL 5JVGH 3CXCJ 5JVHH 5H1SM 1VQ9K 1VQKK 1VQ5K 4U67H 3CCMK 3CC4K 2QEXK 4UY8K 1K9ML 2ZJQH 3PIOH 4IOAH 1NJIL 1K8AL 1KC8L 4V19O 3CF5H 1VQ6K 1YJNK 3CC2K 1YJWK 3CC7K 4WFNH 1Q81L 4IO9H 1VQLK 3J7YL 3G71K 4WFBH 3CCSK 1Q86L 5HL7H 1VQ7K 1QVGJ 5DM6H 5DM7H 3CCRK 3PIPH 1Q7YL 3CPWJ 3J7ZK 3CMAK 1WHIA 3DLLH 1M1KL 4IOCH 3CCEK 1KD1L 5AN9E 1YITK 1K73L 3I56K 3CD6K 2ZJRH 1S72K 1YJ9K 3CCUK 3CCVK 5GAEL 3CCJK 5GAGL 3CMEK 2QA4K 3I55K 1M90L 2OTJK 1KQSJ 5GADL 3G6EK 1YIJK 4WCEH 4WF9H 2ZJPH 1VQ8K 3OW2J 1VQNK 1Q82L 3CCLK 1YI2K 1YHQK 1JJ2J
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G4S K;  1VQO K;  1VQM K;  2OTL K;  1QVF J;  1VQP K;  1W2B J;  1N8R L;  4WFA H;  3CCQ K;  1VQ4 K;  5MLC M;  5GAH L;  5JVG H;  3CXC J;  5JVH H;  5H1S M;  1VQ9 K;  1VQK K;  1VQ5 K;  4U67 H;  3CCM K;  3CC4 K;  2QEX K;  4UY8 K;  1K9M L;  2ZJQ H;  3PIO H;  4IOA H;  1NJI L;  1K8A L;  1KC8 L;  4V19 O;  3CF5 H;  1VQ6 K;  1YJN K;  3CC2 K;  1YJW K;  3CC7 K;  4WFN H;  1Q81 L;  4IO9 H;  1VQL K;  3J7Y L;  3G71 K;  4WFB H;  3CCS K;  1Q86 L;  5HL7 H;  1VQ7 K;  1QVG J;  5DM6 H;  5DM7 H;  3CCR K;  3PIP H;  1Q7Y L;  3CPW J;  3J7Z K;  3CMA K;  1WHI A;  3DLL H;  1M1K L;  4IOC H;  3CCE K;  1KD1 L;  5AN9 E;  1YIT K;  1K73 L;  3I56 K;  3CD6 K;  2ZJR H;  1S72 K;  1YJ9 K;  3CCU K;  3CCV K;  5GAE L;  3CCJ K;  5GAG L;  3CME K;  2QA4 K;  3I55 K;  1M90 L;  2OTJ K;  1KQS J;  5GAD L;  3G6E K;  1YIJ K;  4WCE H;  4WF9 H;  2ZJP H;  1VQ8 K;  3OW2 J;  1VQN K;  1Q82 L;  3CCL K;  1YI2 K;  1YHQ K;  1JJ2 J; 
#chains in the Genus database with same CATH topology
 3G4S K;  1VQO K;  1VQM K;  2OTL K;  1QVF J;  1VQP K;  1W2B J;  1N8R L;  4WFA H;  3CCQ K;  1VQ4 K;  5MLC M;  5GAH L;  5JVG H;  3CXC J;  5JVH H;  5H1S M;  1VQ9 K;  1VQK K;  1VQ5 K;  4U67 H;  3CCM K;  3CC4 K;  2QEX K;  4UY8 K;  1K9M L;  2ZJQ H;  3PIO H;  4IOA H;  1NJI L;  1K8A L;  1KC8 L;  4V19 O;  3CF5 H;  1VQ6 K;  1YJN K;  3CC2 K;  1YJW K;  3CC7 K;  4WFN H;  1Q81 L;  4IO9 H;  1VQL K;  3J7Y L;  3G71 K;  4WFB H;  3CCS K;  1Q86 L;  5HL7 H;  1VQ7 K;  1QVG J;  5DM6 H;  5DM7 H;  3CCR K;  3PIP H;  1Q7Y L;  3CPW J;  3J7Z K;  3CMA K;  1WHI A;  3DLL H;  1M1K L;  4IOC H;  3CCE K;  1KD1 L;  5AN9 E;  1YIT K;  1K73 L;  3I56 K;  3CD6 K;  2ZJR H;  1S72 K;  1YJ9 K;  3CCU K;  3CCV K;  5GAE L;  3CCJ K;  5GAG L;  3CME K;  2QA4 K;  3I55 K;  1M90 L;  2OTJ K;  1KQS J;  5GAD L;  3G6E K;  1YIJ K;  4WCE H;  4WF9 H;  2ZJP H;  1VQ8 K;  3OW2 J;  1VQN K;  1Q82 L;  3CCL K;  1YI2 K;  1YHQ K;  1JJ2 J; 
#chains in the Genus database with same CATH homology
 3G4S K;  1VQO K;  1VQM K;  2OTL K;  1QVF J;  1VQP K;  1W2B J;  1N8R L;  4WFA H;  3CCQ K;  1VQ4 K;  5MLC M;  5GAH L;  5JVG H;  3CXC J;  5JVH H;  5H1S M;  1VQ9 K;  1VQK K;  1VQ5 K;  4U67 H;  3CCM K;  3CC4 K;  2QEX K;  4UY8 K;  1K9M L;  2ZJQ H;  3PIO H;  4IOA H;  1NJI L;  1K8A L;  1KC8 L;  4V19 O;  3CF5 H;  1VQ6 K;  1YJN K;  3CC2 K;  1YJW K;  3CC7 K;  4WFN H;  1Q81 L;  4IO9 H;  1VQL K;  3J7Y L;  3G71 K;  4WFB H;  3CCS K;  1Q86 L;  5HL7 H;  1VQ7 K;  1QVG J;  5DM6 H;  5DM7 H;  3CCR K;  3PIP H;  1Q7Y L;  3CPW J;  3J7Z K;  3CMA K;  1WHI A;  3DLL H;  1M1K L;  4IOC H;  3CCE K;  1KD1 L;  5AN9 E;  1YIT K;  1K73 L;  3I56 K;  3CD6 K;  2ZJR H;  1S72 K;  1YJ9 K;  3CCU K;  3CCV K;  5GAE L;  3CCJ K;  5GAG L;  3CME K;  2QA4 K;  3I55 K;  1M90 L;  2OTJ K;  1KQS J;  5GAD L;  3G6E K;  1YIJ K;  4WCE H;  4WF9 H;  2ZJP H;  1VQ8 K;  3OW2 J;  1VQN K;  1Q82 L;  3CCL K;  1YI2 K;  1YHQ K;  1JJ2 J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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