3CCEK

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535a
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
132
structure length
132
Chain Sequence
MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 31
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 3cceK00
1JJ2J 1VQLK 1YJNK 1Q82L 3I55K 2ZJPH 1QVFJ 3CCSK 3CCEK 3G4SK 5MLCM 3OW2J 1VQ6K 1VQMK 3CF5H 1K9ML 3G71K 3DLLH 2OTLK 1N8RL 3CD6K 1VQOK 3CXCJ 1QVGJ 3CCJK 3CCQK 1YHQK 4IOCH 1Q86L 5GAEL 1YJWK 5JVGH 4IO9H 1VQKK 1YIJK 5DM6H 4IOAH 1Q7YL 3CC4K 5H1SM 1K8AL 4WFAH 3CCLK 4UY8K 2OTJK 5DM7H 5GAHL 1W2BJ 5JVHH 1VQ8K 3CMEK 1YITK 4WFBH 3PIPH 1S72K 3CCMK 1VQNK 3I56K 2ZJQH 1Q81L 4WF9H 1VQ5K 1KC8L 4U67H 1KD1L 2QEXK 4WFNH 3CC7K 3CMAK 2QA4K 3CPWJ 3G6EK 5GADL 3J7ZK 5GAGL 1WHIA 4V19O 1NJIL 1K73L 3CC2K 1YI2K 3J7YL 2ZJRH 1M90L 3CCUK 1M1KL 5HL7H 3CCVK 5AN9E 1VQ4K 1VQ9K 1VQ7K 1KQSJ 4WCEH 3PIOH 3CCRK 1YJ9K 1VQPK
chains in the Genus database with same CATH superfamily
1JJ2J 1VQLK 1YJNK 1Q82L 3I55K 2ZJPH 1QVFJ 3CCSK 3CCEK 3G4SK 5MLCM 3OW2J 1VQ6K 1VQMK 3CF5H 1K9ML 3G71K 3DLLH 2OTLK 1N8RL 3CD6K 1VQOK 3CXCJ 1QVGJ 3CCJK 3CCQK 1YHQK 4IOCH 1Q86L 5GAEL 1YJWK 5JVGH 4IO9H 1VQKK 1YIJK 5DM6H 4IOAH 1Q7YL 3CC4K 5H1SM 1K8AL 4WFAH 3CCLK 4UY8K 2OTJK 5DM7H 5GAHL 1W2BJ 5JVHH 1VQ8K 3CMEK 1YITK 4WFBH 3PIPH 1S72K 3CCMK 1VQNK 3I56K 2ZJQH 1Q81L 4WF9H 1VQ5K 1KC8L 4U67H 1KD1L 2QEXK 4WFNH 3CC7K 3CMAK 2QA4K 3CPWJ 3G6EK 5GADL 3J7ZK 5GAGL 1WHIA 4V19O 1NJIL 1K73L 3CC2K 1YI2K 3J7YL 2ZJRH 1M90L 3CCUK 1M1KL 5HL7H 3CCVK 5AN9E 1VQ4K 1VQ9K 1VQ7K 1KQSJ 4WCEH 3PIOH 3CCRK 1YJ9K 1VQPK
chains in the Genus database with same CATH topology
1JJ2J 1VQLK 1YJNK 1Q82L 3I55K 2ZJPH 1QVFJ 3CCSK 3CCEK 3G4SK 5MLCM 3OW2J 1VQ6K 1VQMK 3CF5H 1K9ML 3G71K 3DLLH 2OTLK 1N8RL 3CD6K 1VQOK 3CXCJ 1QVGJ 3CCJK 3CCQK 1YHQK 4IOCH 1Q86L 5GAEL 1YJWK 5JVGH 4IO9H 1VQKK 1YIJK 5DM6H 4IOAH 1Q7YL 3CC4K 5H1SM 1K8AL 4WFAH 3CCLK 4UY8K 2OTJK 5DM7H 5GAHL 1W2BJ 5JVHH 1VQ8K 3CMEK 1YITK 4WFBH 3PIPH 1S72K 3CCMK 1VQNK 3I56K 2ZJQH 1Q81L 4WF9H 1VQ5K 1KC8L 4U67H 1KD1L 2QEXK 4WFNH 3CC7K 3CMAK 2QA4K 3CPWJ 3G6EK 5GADL 3J7ZK 5GAGL 1WHIA 4V19O 1NJIL 1K73L 3CC2K 1YI2K 3J7YL 2ZJRH 1M90L 3CCUK 1M1KL 5HL7H 3CCVK 5AN9E 1VQ4K 1VQ9K 1VQ7K 1KQSJ 4WCEH 3PIOH 3CCRK 1YJ9K 1VQPK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JJ2 J;  1VQL K;  1YJN K;  1Q82 L;  3I55 K;  2ZJP H;  1QVF J;  3CCS K;  3CCE K;  3G4S K;  5MLC M;  3OW2 J;  1VQ6 K;  1VQM K;  3CF5 H;  1K9M L;  3G71 K;  3DLL H;  2OTL K;  1N8R L;  3CD6 K;  1VQO K;  3CXC J;  1QVG J;  3CCJ K;  3CCQ K;  1YHQ K;  4IOC H;  1Q86 L;  5GAE L;  1YJW K;  5JVG H;  4IO9 H;  1VQK K;  1YIJ K;  5DM6 H;  4IOA H;  1Q7Y L;  3CC4 K;  5H1S M;  1K8A L;  4WFA H;  3CCL K;  4UY8 K;  2OTJ K;  5DM7 H;  5GAH L;  1W2B J;  5JVH H;  1VQ8 K;  3CME K;  1YIT K;  4WFB H;  3PIP H;  1S72 K;  3CCM K;  1VQN K;  3I56 K;  2ZJQ H;  1Q81 L;  4WF9 H;  1VQ5 K;  1KC8 L;  4U67 H;  1KD1 L;  2QEX K;  4WFN H;  3CC7 K;  3CMA K;  2QA4 K;  3CPW J;  3G6E K;  5GAD L;  3J7Z K;  5GAG L;  1WHI A;  4V19 O;  1NJI L;  1K73 L;  3CC2 K;  1YI2 K;  3J7Y L;  2ZJR H;  1M90 L;  3CCU K;  1M1K L;  5HL7 H;  3CCV K;  5AN9 E;  1VQ4 K;  1VQ9 K;  1VQ7 K;  1KQS J;  4WCE H;  3PIO H;  3CCR K;  1YJ9 K;  1VQP K; 
#chains in the Genus database with same CATH topology
 1JJ2 J;  1VQL K;  1YJN K;  1Q82 L;  3I55 K;  2ZJP H;  1QVF J;  3CCS K;  3CCE K;  3G4S K;  5MLC M;  3OW2 J;  1VQ6 K;  1VQM K;  3CF5 H;  1K9M L;  3G71 K;  3DLL H;  2OTL K;  1N8R L;  3CD6 K;  1VQO K;  3CXC J;  1QVG J;  3CCJ K;  3CCQ K;  1YHQ K;  4IOC H;  1Q86 L;  5GAE L;  1YJW K;  5JVG H;  4IO9 H;  1VQK K;  1YIJ K;  5DM6 H;  4IOA H;  1Q7Y L;  3CC4 K;  5H1S M;  1K8A L;  4WFA H;  3CCL K;  4UY8 K;  2OTJ K;  5DM7 H;  5GAH L;  1W2B J;  5JVH H;  1VQ8 K;  3CME K;  1YIT K;  4WFB H;  3PIP H;  1S72 K;  3CCM K;  1VQN K;  3I56 K;  2ZJQ H;  1Q81 L;  4WF9 H;  1VQ5 K;  1KC8 L;  4U67 H;  1KD1 L;  2QEX K;  4WFN H;  3CC7 K;  3CMA K;  2QA4 K;  3CPW J;  3G6E K;  5GAD L;  3J7Z K;  5GAG L;  1WHI A;  4V19 O;  1NJI L;  1K73 L;  3CC2 K;  1YI2 K;  3J7Y L;  2ZJR H;  1M90 L;  3CCU K;  1M1K L;  5HL7 H;  3CCV K;  5AN9 E;  1VQ4 K;  1VQ9 K;  1VQ7 K;  1KQS J;  4WCE H;  3PIO H;  3CCR K;  1YJ9 K;  1VQP K; 
#chains in the Genus database with same CATH homology
 1JJ2 J;  1VQL K;  1YJN K;  1Q82 L;  3I55 K;  2ZJP H;  1QVF J;  3CCS K;  3CCE K;  3G4S K;  5MLC M;  3OW2 J;  1VQ6 K;  1VQM K;  3CF5 H;  1K9M L;  3G71 K;  3DLL H;  2OTL K;  1N8R L;  3CD6 K;  1VQO K;  3CXC J;  1QVG J;  3CCJ K;  3CCQ K;  1YHQ K;  4IOC H;  1Q86 L;  5GAE L;  1YJW K;  5JVG H;  4IO9 H;  1VQK K;  1YIJ K;  5DM6 H;  4IOA H;  1Q7Y L;  3CC4 K;  5H1S M;  1K8A L;  4WFA H;  3CCL K;  4UY8 K;  2OTJ K;  5DM7 H;  5GAH L;  1W2B J;  5JVH H;  1VQ8 K;  3CME K;  1YIT K;  4WFB H;  3PIP H;  1S72 K;  3CCM K;  1VQN K;  3I56 K;  2ZJQ H;  1Q81 L;  4WF9 H;  1VQ5 K;  1KC8 L;  4U67 H;  1KD1 L;  2QEX K;  4WFN H;  3CC7 K;  3CMA K;  2QA4 K;  3CPW J;  3G6E K;  5GAD L;  3J7Z K;  5GAG L;  1WHI A;  4V19 O;  1NJI L;  1K73 L;  3CC2 K;  1YI2 K;  3J7Y L;  2ZJR H;  1M90 L;  3CCU K;  1M1K L;  5HL7 H;  3CCV K;  5AN9 E;  1VQ4 K;  1VQ9 K;  1VQ7 K;  1KQS J;  4WCE H;  3PIO H;  3CCR K;  1YJ9 K;  1VQP K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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