3CCJK

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
132
structure length
132
Chain Sequence
MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 24
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 3ccjK00
1KD1L 1QVFJ 3PIOH 1YJNK 1VQ4K 4WF9H 1VQMK 1JJ2J 3CCQK 3I55K 1VQ5K 2ZJQH 3CCMK 1N8RL 1YJWK 1M1KL 5MLCM 3CCJK 3DLLH 1VQLK 3CCEK 5AN9E 1YHQK 3CC4K 5HL7H 4IOAH 1Q7YL 3CD6K 1WHIA 3CC7K 3CMEK 1QVGJ 4U67H 5JVGH 1K9ML 4UY8K 4WFNH 5DM6H 1YI2K 3CPWJ 1Q82L 1YITK 1YJ9K 2QA4K 4V19O 3CC2K 5GADL 1VQNK 3OW2J 1Q86L 1KC8L 3CXCJ 1VQ8K 5JVHH 1YIJK 1S72K 1VQ9K 3CF5H 3CCSK 4IO9H 1K73L 3CCLK 4WFBH 4WCEH 5H1SM 1VQOK 3J7ZK 1VQPK 2QEXK 5GAHL 2OTLK 3G6EK 3CMAK 1Q81L 1KQSJ 2OTJK 1M90L 3PIPH 1W2BJ 2ZJPH 3J7YL 4IOCH 3G71K 4WFAH 5GAEL 3I56K 2ZJRH 1VQ7K 3CCRK 3CCUK 1NJIL 3CCVK 1VQKK 5GAGL 1K8AL 5DM7H 1VQ6K 3G4SK
chains in the Genus database with same CATH superfamily
1KD1L 1QVFJ 3PIOH 1YJNK 1VQ4K 4WF9H 1VQMK 1JJ2J 3CCQK 3I55K 1VQ5K 2ZJQH 3CCMK 1N8RL 1YJWK 1M1KL 5MLCM 3CCJK 3DLLH 1VQLK 3CCEK 5AN9E 1YHQK 3CC4K 5HL7H 4IOAH 1Q7YL 3CD6K 1WHIA 3CC7K 3CMEK 1QVGJ 4U67H 5JVGH 1K9ML 4UY8K 4WFNH 5DM6H 1YI2K 3CPWJ 1Q82L 1YITK 1YJ9K 2QA4K 4V19O 3CC2K 5GADL 1VQNK 3OW2J 1Q86L 1KC8L 3CXCJ 1VQ8K 5JVHH 1YIJK 1S72K 1VQ9K 3CF5H 3CCSK 4IO9H 1K73L 3CCLK 4WFBH 4WCEH 5H1SM 1VQOK 3J7ZK 1VQPK 2QEXK 5GAHL 2OTLK 3G6EK 3CMAK 1Q81L 1KQSJ 2OTJK 1M90L 3PIPH 1W2BJ 2ZJPH 3J7YL 4IOCH 3G71K 4WFAH 5GAEL 3I56K 2ZJRH 1VQ7K 3CCRK 3CCUK 1NJIL 3CCVK 1VQKK 5GAGL 1K8AL 5DM7H 1VQ6K 3G4SK
chains in the Genus database with same CATH topology
1KD1L 1QVFJ 3PIOH 1YJNK 1VQ4K 4WF9H 1VQMK 1JJ2J 3CCQK 3I55K 1VQ5K 2ZJQH 3CCMK 1N8RL 1YJWK 1M1KL 5MLCM 3CCJK 3DLLH 1VQLK 3CCEK 5AN9E 1YHQK 3CC4K 5HL7H 4IOAH 1Q7YL 3CD6K 1WHIA 3CC7K 3CMEK 1QVGJ 4U67H 5JVGH 1K9ML 4UY8K 4WFNH 5DM6H 1YI2K 3CPWJ 1Q82L 1YITK 1YJ9K 2QA4K 4V19O 3CC2K 5GADL 1VQNK 3OW2J 1Q86L 1KC8L 3CXCJ 1VQ8K 5JVHH 1YIJK 1S72K 1VQ9K 3CF5H 3CCSK 4IO9H 1K73L 3CCLK 4WFBH 4WCEH 5H1SM 1VQOK 3J7ZK 1VQPK 2QEXK 5GAHL 2OTLK 3G6EK 3CMAK 1Q81L 1KQSJ 2OTJK 1M90L 3PIPH 1W2BJ 2ZJPH 3J7YL 4IOCH 3G71K 4WFAH 5GAEL 3I56K 2ZJRH 1VQ7K 3CCRK 3CCUK 1NJIL 3CCVK 1VQKK 5GAGL 1K8AL 5DM7H 1VQ6K 3G4SK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KD1 L;  1QVF J;  3PIO H;  1YJN K;  1VQ4 K;  4WF9 H;  1VQM K;  1JJ2 J;  3CCQ K;  3I55 K;  1VQ5 K;  2ZJQ H;  3CCM K;  1N8R L;  1YJW K;  1M1K L;  5MLC M;  3CCJ K;  3DLL H;  1VQL K;  3CCE K;  5AN9 E;  1YHQ K;  3CC4 K;  5HL7 H;  4IOA H;  1Q7Y L;  3CD6 K;  1WHI A;  3CC7 K;  3CME K;  1QVG J;  4U67 H;  5JVG H;  1K9M L;  4UY8 K;  4WFN H;  5DM6 H;  1YI2 K;  3CPW J;  1Q82 L;  1YIT K;  1YJ9 K;  2QA4 K;  4V19 O;  3CC2 K;  5GAD L;  1VQN K;  3OW2 J;  1Q86 L;  1KC8 L;  3CXC J;  1VQ8 K;  5JVH H;  1YIJ K;  1S72 K;  1VQ9 K;  3CF5 H;  3CCS K;  4IO9 H;  1K73 L;  3CCL K;  4WFB H;  4WCE H;  5H1S M;  1VQO K;  3J7Z K;  1VQP K;  2QEX K;  5GAH L;  2OTL K;  3G6E K;  3CMA K;  1Q81 L;  1KQS J;  2OTJ K;  1M90 L;  3PIP H;  1W2B J;  2ZJP H;  3J7Y L;  4IOC H;  3G71 K;  4WFA H;  5GAE L;  3I56 K;  2ZJR H;  1VQ7 K;  3CCR K;  3CCU K;  1NJI L;  3CCV K;  1VQK K;  5GAG L;  1K8A L;  5DM7 H;  1VQ6 K;  3G4S K; 
#chains in the Genus database with same CATH topology
 1KD1 L;  1QVF J;  3PIO H;  1YJN K;  1VQ4 K;  4WF9 H;  1VQM K;  1JJ2 J;  3CCQ K;  3I55 K;  1VQ5 K;  2ZJQ H;  3CCM K;  1N8R L;  1YJW K;  1M1K L;  5MLC M;  3CCJ K;  3DLL H;  1VQL K;  3CCE K;  5AN9 E;  1YHQ K;  3CC4 K;  5HL7 H;  4IOA H;  1Q7Y L;  3CD6 K;  1WHI A;  3CC7 K;  3CME K;  1QVG J;  4U67 H;  5JVG H;  1K9M L;  4UY8 K;  4WFN H;  5DM6 H;  1YI2 K;  3CPW J;  1Q82 L;  1YIT K;  1YJ9 K;  2QA4 K;  4V19 O;  3CC2 K;  5GAD L;  1VQN K;  3OW2 J;  1Q86 L;  1KC8 L;  3CXC J;  1VQ8 K;  5JVH H;  1YIJ K;  1S72 K;  1VQ9 K;  3CF5 H;  3CCS K;  4IO9 H;  1K73 L;  3CCL K;  4WFB H;  4WCE H;  5H1S M;  1VQO K;  3J7Z K;  1VQP K;  2QEX K;  5GAH L;  2OTL K;  3G6E K;  3CMA K;  1Q81 L;  1KQS J;  2OTJ K;  1M90 L;  3PIP H;  1W2B J;  2ZJP H;  3J7Y L;  4IOC H;  3G71 K;  4WFA H;  5GAE L;  3I56 K;  2ZJR H;  1VQ7 K;  3CCR K;  3CCU K;  1NJI L;  3CCV K;  1VQK K;  5GAG L;  1K8A L;  5DM7 H;  1VQ6 K;  3G4S K; 
#chains in the Genus database with same CATH homology
 1KD1 L;  1QVF J;  3PIO H;  1YJN K;  1VQ4 K;  4WF9 H;  1VQM K;  1JJ2 J;  3CCQ K;  3I55 K;  1VQ5 K;  2ZJQ H;  3CCM K;  1N8R L;  1YJW K;  1M1K L;  5MLC M;  3CCJ K;  3DLL H;  1VQL K;  3CCE K;  5AN9 E;  1YHQ K;  3CC4 K;  5HL7 H;  4IOA H;  1Q7Y L;  3CD6 K;  1WHI A;  3CC7 K;  3CME K;  1QVG J;  4U67 H;  5JVG H;  1K9M L;  4UY8 K;  4WFN H;  5DM6 H;  1YI2 K;  3CPW J;  1Q82 L;  1YIT K;  1YJ9 K;  2QA4 K;  4V19 O;  3CC2 K;  5GAD L;  1VQN K;  3OW2 J;  1Q86 L;  1KC8 L;  3CXC J;  1VQ8 K;  5JVH H;  1YIJ K;  1S72 K;  1VQ9 K;  3CF5 H;  3CCS K;  4IO9 H;  1K73 L;  3CCL K;  4WFB H;  4WCE H;  5H1S M;  1VQO K;  3J7Z K;  1VQP K;  2QEX K;  5GAH L;  2OTL K;  3G6E K;  3CMA K;  1Q81 L;  1KQS J;  2OTJ K;  1M90 L;  3PIP H;  1W2B J;  2ZJP H;  3J7Y L;  4IOC H;  3G71 K;  4WFA H;  5GAE L;  3I56 K;  2ZJR H;  1VQ7 K;  3CCR K;  3CCU K;  1NJI L;  3CCV K;  1VQK K;  5GAG L;  1K8A L;  5DM7 H;  1VQ6 K;  3G4S K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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