3CCMK

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
132
structure length
132
Chain Sequence
MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 31
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 3ccmK00
5GAGL 3CF5H 2QEXK 5JVHH 1YHQK 4WFAH 3CCMK 3J7ZK 1VQLK 1K8AL 1VQNK 1JJ2J 2OTLK 3CMEK 4WF9H 1YI2K 2ZJQH 1YJNK 1YJWK 5HL7H 5DM6H 3CCQK 1M90L 3G71K 1S72K 4WCEH 3CCJK 3CCSK 1Q7YL 4IOAH 5AN9E 4WFNH 1KC8L 2OTJK 1NJIL 3CC7K 3OW2J 1QVGJ 3I56K 1KQSJ 1QVFJ 1VQPK 1VQ6K 3CPWJ 3G4SK 2QA4K 3CD6K 1Q82L 5GAEL 1VQ4K 4V19O 3PIPH 1M1KL 5GAHL 1Q81L 2ZJRH 5JVGH 5GADL 1W2BJ 1VQ7K 3DLLH 3CCVK 3G6EK 1K73L 4IO9H 3CCEK 1YITK 2ZJPH 5H1SM 3CXCJ 3CCLK 3I55K 3CCUK 5MLCM 1VQ8K 4UY8K 4IOCH 3CC4K 1KD1L 1YIJK 1K9ML 1VQ9K 4WFBH 1VQ5K 3PIOH 5DM7H 1Q86L 1YJ9K 3CMAK 3CC2K 3CCRK 3J7YL 1VQMK 1N8RL 1VQKK 4U67H 1WHIA 1VQOK
chains in the Genus database with same CATH superfamily
5GAGL 3CF5H 2QEXK 5JVHH 1YHQK 4WFAH 3CCMK 3J7ZK 1VQLK 1K8AL 1VQNK 1JJ2J 2OTLK 3CMEK 4WF9H 1YI2K 2ZJQH 1YJNK 1YJWK 5HL7H 5DM6H 3CCQK 1M90L 3G71K 1S72K 4WCEH 3CCJK 3CCSK 1Q7YL 4IOAH 5AN9E 4WFNH 1KC8L 2OTJK 1NJIL 3CC7K 3OW2J 1QVGJ 3I56K 1KQSJ 1QVFJ 1VQPK 1VQ6K 3CPWJ 3G4SK 2QA4K 3CD6K 1Q82L 5GAEL 1VQ4K 4V19O 3PIPH 1M1KL 5GAHL 1Q81L 2ZJRH 5JVGH 5GADL 1W2BJ 1VQ7K 3DLLH 3CCVK 3G6EK 1K73L 4IO9H 3CCEK 1YITK 2ZJPH 5H1SM 3CXCJ 3CCLK 3I55K 3CCUK 5MLCM 1VQ8K 4UY8K 4IOCH 3CC4K 1KD1L 1YIJK 1K9ML 1VQ9K 4WFBH 1VQ5K 3PIOH 5DM7H 1Q86L 1YJ9K 3CMAK 3CC2K 3CCRK 3J7YL 1VQMK 1N8RL 1VQKK 4U67H 1WHIA 1VQOK
chains in the Genus database with same CATH topology
5GAGL 3CF5H 2QEXK 5JVHH 1YHQK 4WFAH 3CCMK 3J7ZK 1VQLK 1K8AL 1VQNK 1JJ2J 2OTLK 3CMEK 4WF9H 1YI2K 2ZJQH 1YJNK 1YJWK 5HL7H 5DM6H 3CCQK 1M90L 3G71K 1S72K 4WCEH 3CCJK 3CCSK 1Q7YL 4IOAH 5AN9E 4WFNH 1KC8L 2OTJK 1NJIL 3CC7K 3OW2J 1QVGJ 3I56K 1KQSJ 1QVFJ 1VQPK 1VQ6K 3CPWJ 3G4SK 2QA4K 3CD6K 1Q82L 5GAEL 1VQ4K 4V19O 3PIPH 1M1KL 5GAHL 1Q81L 2ZJRH 5JVGH 5GADL 1W2BJ 1VQ7K 3DLLH 3CCVK 3G6EK 1K73L 4IO9H 3CCEK 1YITK 2ZJPH 5H1SM 3CXCJ 3CCLK 3I55K 3CCUK 5MLCM 1VQ8K 4UY8K 4IOCH 3CC4K 1KD1L 1YIJK 1K9ML 1VQ9K 4WFBH 1VQ5K 3PIOH 5DM7H 1Q86L 1YJ9K 3CMAK 3CC2K 3CCRK 3J7YL 1VQMK 1N8RL 1VQKK 4U67H 1WHIA 1VQOK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GAG L;  3CF5 H;  2QEX K;  5JVH H;  1YHQ K;  4WFA H;  3CCM K;  3J7Z K;  1VQL K;  1K8A L;  1VQN K;  1JJ2 J;  2OTL K;  3CME K;  4WF9 H;  1YI2 K;  2ZJQ H;  1YJN K;  1YJW K;  5HL7 H;  5DM6 H;  3CCQ K;  1M90 L;  3G71 K;  1S72 K;  4WCE H;  3CCJ K;  3CCS K;  1Q7Y L;  4IOA H;  5AN9 E;  4WFN H;  1KC8 L;  2OTJ K;  1NJI L;  3CC7 K;  3OW2 J;  1QVG J;  3I56 K;  1KQS J;  1QVF J;  1VQP K;  1VQ6 K;  3CPW J;  3G4S K;  2QA4 K;  3CD6 K;  1Q82 L;  5GAE L;  1VQ4 K;  4V19 O;  3PIP H;  1M1K L;  5GAH L;  1Q81 L;  2ZJR H;  5JVG H;  5GAD L;  1W2B J;  1VQ7 K;  3DLL H;  3CCV K;  3G6E K;  1K73 L;  4IO9 H;  3CCE K;  1YIT K;  2ZJP H;  5H1S M;  3CXC J;  3CCL K;  3I55 K;  3CCU K;  5MLC M;  1VQ8 K;  4UY8 K;  4IOC H;  3CC4 K;  1KD1 L;  1YIJ K;  1K9M L;  1VQ9 K;  4WFB H;  1VQ5 K;  3PIO H;  5DM7 H;  1Q86 L;  1YJ9 K;  3CMA K;  3CC2 K;  3CCR K;  3J7Y L;  1VQM K;  1N8R L;  1VQK K;  4U67 H;  1WHI A;  1VQO K; 
#chains in the Genus database with same CATH topology
 5GAG L;  3CF5 H;  2QEX K;  5JVH H;  1YHQ K;  4WFA H;  3CCM K;  3J7Z K;  1VQL K;  1K8A L;  1VQN K;  1JJ2 J;  2OTL K;  3CME K;  4WF9 H;  1YI2 K;  2ZJQ H;  1YJN K;  1YJW K;  5HL7 H;  5DM6 H;  3CCQ K;  1M90 L;  3G71 K;  1S72 K;  4WCE H;  3CCJ K;  3CCS K;  1Q7Y L;  4IOA H;  5AN9 E;  4WFN H;  1KC8 L;  2OTJ K;  1NJI L;  3CC7 K;  3OW2 J;  1QVG J;  3I56 K;  1KQS J;  1QVF J;  1VQP K;  1VQ6 K;  3CPW J;  3G4S K;  2QA4 K;  3CD6 K;  1Q82 L;  5GAE L;  1VQ4 K;  4V19 O;  3PIP H;  1M1K L;  5GAH L;  1Q81 L;  2ZJR H;  5JVG H;  5GAD L;  1W2B J;  1VQ7 K;  3DLL H;  3CCV K;  3G6E K;  1K73 L;  4IO9 H;  3CCE K;  1YIT K;  2ZJP H;  5H1S M;  3CXC J;  3CCL K;  3I55 K;  3CCU K;  5MLC M;  1VQ8 K;  4UY8 K;  4IOC H;  3CC4 K;  1KD1 L;  1YIJ K;  1K9M L;  1VQ9 K;  4WFB H;  1VQ5 K;  3PIO H;  5DM7 H;  1Q86 L;  1YJ9 K;  3CMA K;  3CC2 K;  3CCR K;  3J7Y L;  1VQM K;  1N8R L;  1VQK K;  4U67 H;  1WHI A;  1VQO K; 
#chains in the Genus database with same CATH homology
 5GAG L;  3CF5 H;  2QEX K;  5JVH H;  1YHQ K;  4WFA H;  3CCM K;  3J7Z K;  1VQL K;  1K8A L;  1VQN K;  1JJ2 J;  2OTL K;  3CME K;  4WF9 H;  1YI2 K;  2ZJQ H;  1YJN K;  1YJW K;  5HL7 H;  5DM6 H;  3CCQ K;  1M90 L;  3G71 K;  1S72 K;  4WCE H;  3CCJ K;  3CCS K;  1Q7Y L;  4IOA H;  5AN9 E;  4WFN H;  1KC8 L;  2OTJ K;  1NJI L;  3CC7 K;  3OW2 J;  1QVG J;  3I56 K;  1KQS J;  1QVF J;  1VQP K;  1VQ6 K;  3CPW J;  3G4S K;  2QA4 K;  3CD6 K;  1Q82 L;  5GAE L;  1VQ4 K;  4V19 O;  3PIP H;  1M1K L;  5GAH L;  1Q81 L;  2ZJR H;  5JVG H;  5GAD L;  1W2B J;  1VQ7 K;  3DLL H;  3CCV K;  3G6E K;  1K73 L;  4IO9 H;  3CCE K;  1YIT K;  2ZJP H;  5H1S M;  3CXC J;  3CCL K;  3I55 K;  3CCU K;  5MLC M;  1VQ8 K;  4UY8 K;  4IOC H;  3CC4 K;  1KD1 L;  1YIJ K;  1K9M L;  1VQ9 K;  4WFB H;  1VQ5 K;  3PIO H;  5DM7 H;  1Q86 L;  1YJ9 K;  3CMA K;  3CC2 K;  3CCR K;  3J7Y L;  1VQM K;  1N8R L;  1VQK K;  4U67 H;  1WHI A;  1VQO K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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