3CCRK

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
132
structure length
132
Chain Sequence
MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 28
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 3ccrK00
1YJNK 2ZJQH 3CCJK 1VQ5K 4V19O 2OTJK 3CCRK 1KD1L 1YIJK 5DM7H 1VQNK 1M1KL 1N8RL 2QEXK 3CCSK 1VQMK 1Q82L 1Q86L 5DM6H 2ZJPH 3G4SK 1VQPK 3CC4K 1M90L 1Q7YL 2OTLK 5GADL 5GAHL 1YHQK 1VQLK 1VQOK 4IOCH 4WFAH 3G6EK 2ZJRH 5JVHH 1VQKK 3CCVK 1VQ8K 3CPWJ 4IO9H 3CCLK 5AN9E 1KC8L 5MLCM 1VQ9K 3CC7K 5GAGL 3I55K 1NJIL 1YITK 1YJ9K 3J7ZK 2QA4K 1JJ2J 1VQ4K 3CD6K 4U67H 4UY8K 1K9ML 3DLLH 3CXCJ 3CC2K 3CCMK 4WFNH 5H1SM 1VQ7K 1QVGJ 1Q81L 1VQ6K 3CCQK 5HL7H 3J7YL 3G71K 5GAEL 5JVGH 1KQSJ 4WFBH 3CCEK 3CMEK 3PIOH 1K8AL 4WF9H 4WCEH 3PIPH 1K73L 1YI2K 1YJWK 3CF5H 3OW2J 3CCUK 1W2BJ 3I56K 4IOAH 1S72K 1QVFJ 1WHIA 3CMAK
chains in the Genus database with same CATH superfamily
1YJNK 2ZJQH 3CCJK 1VQ5K 4V19O 2OTJK 3CCRK 1KD1L 1YIJK 5DM7H 1VQNK 1M1KL 1N8RL 2QEXK 3CCSK 1VQMK 1Q82L 1Q86L 5DM6H 2ZJPH 3G4SK 1VQPK 3CC4K 1M90L 1Q7YL 2OTLK 5GADL 5GAHL 1YHQK 1VQLK 1VQOK 4IOCH 4WFAH 3G6EK 2ZJRH 5JVHH 1VQKK 3CCVK 1VQ8K 3CPWJ 4IO9H 3CCLK 5AN9E 1KC8L 5MLCM 1VQ9K 3CC7K 5GAGL 3I55K 1NJIL 1YITK 1YJ9K 3J7ZK 2QA4K 1JJ2J 1VQ4K 3CD6K 4U67H 4UY8K 1K9ML 3DLLH 3CXCJ 3CC2K 3CCMK 4WFNH 5H1SM 1VQ7K 1QVGJ 1Q81L 1VQ6K 3CCQK 5HL7H 3J7YL 3G71K 5GAEL 5JVGH 1KQSJ 4WFBH 3CCEK 3CMEK 3PIOH 1K8AL 4WF9H 4WCEH 3PIPH 1K73L 1YI2K 1YJWK 3CF5H 3OW2J 3CCUK 1W2BJ 3I56K 4IOAH 1S72K 1QVFJ 1WHIA 3CMAK
chains in the Genus database with same CATH topology
1YJNK 2ZJQH 3CCJK 1VQ5K 4V19O 2OTJK 3CCRK 1KD1L 1YIJK 5DM7H 1VQNK 1M1KL 1N8RL 2QEXK 3CCSK 1VQMK 1Q82L 1Q86L 5DM6H 2ZJPH 3G4SK 1VQPK 3CC4K 1M90L 1Q7YL 2OTLK 5GADL 5GAHL 1YHQK 1VQLK 1VQOK 4IOCH 4WFAH 3G6EK 2ZJRH 5JVHH 1VQKK 3CCVK 1VQ8K 3CPWJ 4IO9H 3CCLK 5AN9E 1KC8L 5MLCM 1VQ9K 3CC7K 5GAGL 3I55K 1NJIL 1YITK 1YJ9K 3J7ZK 2QA4K 1JJ2J 1VQ4K 3CD6K 4U67H 4UY8K 1K9ML 3DLLH 3CXCJ 3CC2K 3CCMK 4WFNH 5H1SM 1VQ7K 1QVGJ 1Q81L 1VQ6K 3CCQK 5HL7H 3J7YL 3G71K 5GAEL 5JVGH 1KQSJ 4WFBH 3CCEK 3CMEK 3PIOH 1K8AL 4WF9H 4WCEH 3PIPH 1K73L 1YI2K 1YJWK 3CF5H 3OW2J 3CCUK 1W2BJ 3I56K 4IOAH 1S72K 1QVFJ 1WHIA 3CMAK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YJN K;  2ZJQ H;  3CCJ K;  1VQ5 K;  4V19 O;  2OTJ K;  3CCR K;  1KD1 L;  1YIJ K;  5DM7 H;  1VQN K;  1M1K L;  1N8R L;  2QEX K;  3CCS K;  1VQM K;  1Q82 L;  1Q86 L;  5DM6 H;  2ZJP H;  3G4S K;  1VQP K;  3CC4 K;  1M90 L;  1Q7Y L;  2OTL K;  5GAD L;  5GAH L;  1YHQ K;  1VQL K;  1VQO K;  4IOC H;  4WFA H;  3G6E K;  2ZJR H;  5JVH H;  1VQK K;  3CCV K;  1VQ8 K;  3CPW J;  4IO9 H;  3CCL K;  5AN9 E;  1KC8 L;  5MLC M;  1VQ9 K;  3CC7 K;  5GAG L;  3I55 K;  1NJI L;  1YIT K;  1YJ9 K;  3J7Z K;  2QA4 K;  1JJ2 J;  1VQ4 K;  3CD6 K;  4U67 H;  4UY8 K;  1K9M L;  3DLL H;  3CXC J;  3CC2 K;  3CCM K;  4WFN H;  5H1S M;  1VQ7 K;  1QVG J;  1Q81 L;  1VQ6 K;  3CCQ K;  5HL7 H;  3J7Y L;  3G71 K;  5GAE L;  5JVG H;  1KQS J;  4WFB H;  3CCE K;  3CME K;  3PIO H;  1K8A L;  4WF9 H;  4WCE H;  3PIP H;  1K73 L;  1YI2 K;  1YJW K;  3CF5 H;  3OW2 J;  3CCU K;  1W2B J;  3I56 K;  4IOA H;  1S72 K;  1QVF J;  1WHI A;  3CMA K; 
#chains in the Genus database with same CATH topology
 1YJN K;  2ZJQ H;  3CCJ K;  1VQ5 K;  4V19 O;  2OTJ K;  3CCR K;  1KD1 L;  1YIJ K;  5DM7 H;  1VQN K;  1M1K L;  1N8R L;  2QEX K;  3CCS K;  1VQM K;  1Q82 L;  1Q86 L;  5DM6 H;  2ZJP H;  3G4S K;  1VQP K;  3CC4 K;  1M90 L;  1Q7Y L;  2OTL K;  5GAD L;  5GAH L;  1YHQ K;  1VQL K;  1VQO K;  4IOC H;  4WFA H;  3G6E K;  2ZJR H;  5JVH H;  1VQK K;  3CCV K;  1VQ8 K;  3CPW J;  4IO9 H;  3CCL K;  5AN9 E;  1KC8 L;  5MLC M;  1VQ9 K;  3CC7 K;  5GAG L;  3I55 K;  1NJI L;  1YIT K;  1YJ9 K;  3J7Z K;  2QA4 K;  1JJ2 J;  1VQ4 K;  3CD6 K;  4U67 H;  4UY8 K;  1K9M L;  3DLL H;  3CXC J;  3CC2 K;  3CCM K;  4WFN H;  5H1S M;  1VQ7 K;  1QVG J;  1Q81 L;  1VQ6 K;  3CCQ K;  5HL7 H;  3J7Y L;  3G71 K;  5GAE L;  5JVG H;  1KQS J;  4WFB H;  3CCE K;  3CME K;  3PIO H;  1K8A L;  4WF9 H;  4WCE H;  3PIP H;  1K73 L;  1YI2 K;  1YJW K;  3CF5 H;  3OW2 J;  3CCU K;  1W2B J;  3I56 K;  4IOA H;  1S72 K;  1QVF J;  1WHI A;  3CMA K; 
#chains in the Genus database with same CATH homology
 1YJN K;  2ZJQ H;  3CCJ K;  1VQ5 K;  4V19 O;  2OTJ K;  3CCR K;  1KD1 L;  1YIJ K;  5DM7 H;  1VQN K;  1M1K L;  1N8R L;  2QEX K;  3CCS K;  1VQM K;  1Q82 L;  1Q86 L;  5DM6 H;  2ZJP H;  3G4S K;  1VQP K;  3CC4 K;  1M90 L;  1Q7Y L;  2OTL K;  5GAD L;  5GAH L;  1YHQ K;  1VQL K;  1VQO K;  4IOC H;  4WFA H;  3G6E K;  2ZJR H;  5JVH H;  1VQK K;  3CCV K;  1VQ8 K;  3CPW J;  4IO9 H;  3CCL K;  5AN9 E;  1KC8 L;  5MLC M;  1VQ9 K;  3CC7 K;  5GAG L;  3I55 K;  1NJI L;  1YIT K;  1YJ9 K;  3J7Z K;  2QA4 K;  1JJ2 J;  1VQ4 K;  3CD6 K;  4U67 H;  4UY8 K;  1K9M L;  3DLL H;  3CXC J;  3CC2 K;  3CCM K;  4WFN H;  5H1S M;  1VQ7 K;  1QVG J;  1Q81 L;  1VQ6 K;  3CCQ K;  5HL7 H;  3J7Y L;  3G71 K;  5GAE L;  5JVG H;  1KQS J;  4WFB H;  3CCE K;  3CME K;  3PIO H;  1K8A L;  4WF9 H;  4WCE H;  3PIP H;  1K73 L;  1YI2 K;  1YJW K;  3CF5 H;  3OW2 J;  3CCU K;  1W2B J;  3I56 K;  4IOA H;  1S72 K;  1QVF J;  1WHI A;  3CMA K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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