3CCUK

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482c
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
132
structure length
132
Chain Sequence
MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 30
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 3ccuK00
3CCQK 3PIPH 1K9ML 1VQ7K 1VQ8K 1KD1L 1Q82L 3CCLK 1YHQK 3CCVK 1VQLK 2ZJQH 1K73L 1VQ9K 1VQPK 1M1KL 1NJIL 5JVHH 1KQSJ 3CXCJ 2QEXK 3CCJK 2ZJRH 3CC2K 3CCRK 3G71K 1VQNK 3J7ZK 5GAEL 1VQOK 1VQ6K 3CCSK 4V19O 4WFBH 1YJWK 1YJ9K 3CPWJ 5DM6H 1VQ4K 1KC8L 3CC4K 1Q81L 1YI2K 2OTLK 4WF9H 3PIOH 3CCMK 3CCUK 4IO9H 1QVGJ 1M90L 3J7YL 5AN9E 5H1SM 3CD6K 5MLCM 3G6EK 4WCEH 3CF5H 5JVGH 3CCEK 3CMAK 3I56K 3CC7K 5GADL 4WFNH 5GAHL 1Q7YL 1Q86L 1JJ2J 1VQKK 1W2BJ 1YJNK 1S72K 3G4SK 3OW2J 1K8AL 4IOCH 4IOAH 3I55K 4UY8K 1QVFJ 5HL7H 2ZJPH 1YITK 1N8RL 5GAGL 5DM7H 1WHIA 1YIJK 2OTJK 1VQ5K 2QA4K 4WFAH 4U67H 3DLLH 3CMEK 1VQMK
chains in the Genus database with same CATH superfamily
3CCQK 3PIPH 1K9ML 1VQ7K 1VQ8K 1KD1L 1Q82L 3CCLK 1YHQK 3CCVK 1VQLK 2ZJQH 1K73L 1VQ9K 1VQPK 1M1KL 1NJIL 5JVHH 1KQSJ 3CXCJ 2QEXK 3CCJK 2ZJRH 3CC2K 3CCRK 3G71K 1VQNK 3J7ZK 5GAEL 1VQOK 1VQ6K 3CCSK 4V19O 4WFBH 1YJWK 1YJ9K 3CPWJ 5DM6H 1VQ4K 1KC8L 3CC4K 1Q81L 1YI2K 2OTLK 4WF9H 3PIOH 3CCMK 3CCUK 4IO9H 1QVGJ 1M90L 3J7YL 5AN9E 5H1SM 3CD6K 5MLCM 3G6EK 4WCEH 3CF5H 5JVGH 3CCEK 3CMAK 3I56K 3CC7K 5GADL 4WFNH 5GAHL 1Q7YL 1Q86L 1JJ2J 1VQKK 1W2BJ 1YJNK 1S72K 3G4SK 3OW2J 1K8AL 4IOCH 4IOAH 3I55K 4UY8K 1QVFJ 5HL7H 2ZJPH 1YITK 1N8RL 5GAGL 5DM7H 1WHIA 1YIJK 2OTJK 1VQ5K 2QA4K 4WFAH 4U67H 3DLLH 3CMEK 1VQMK
chains in the Genus database with same CATH topology
3CCQK 3PIPH 1K9ML 1VQ7K 1VQ8K 1KD1L 1Q82L 3CCLK 1YHQK 3CCVK 1VQLK 2ZJQH 1K73L 1VQ9K 1VQPK 1M1KL 1NJIL 5JVHH 1KQSJ 3CXCJ 2QEXK 3CCJK 2ZJRH 3CC2K 3CCRK 3G71K 1VQNK 3J7ZK 5GAEL 1VQOK 1VQ6K 3CCSK 4V19O 4WFBH 1YJWK 1YJ9K 3CPWJ 5DM6H 1VQ4K 1KC8L 3CC4K 1Q81L 1YI2K 2OTLK 4WF9H 3PIOH 3CCMK 3CCUK 4IO9H 1QVGJ 1M90L 3J7YL 5AN9E 5H1SM 3CD6K 5MLCM 3G6EK 4WCEH 3CF5H 5JVGH 3CCEK 3CMAK 3I56K 3CC7K 5GADL 4WFNH 5GAHL 1Q7YL 1Q86L 1JJ2J 1VQKK 1W2BJ 1YJNK 1S72K 3G4SK 3OW2J 1K8AL 4IOCH 4IOAH 3I55K 4UY8K 1QVFJ 5HL7H 2ZJPH 1YITK 1N8RL 5GAGL 5DM7H 1WHIA 1YIJK 2OTJK 1VQ5K 2QA4K 4WFAH 4U67H 3DLLH 3CMEK 1VQMK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCQ K;  3PIP H;  1K9M L;  1VQ7 K;  1VQ8 K;  1KD1 L;  1Q82 L;  3CCL K;  1YHQ K;  3CCV K;  1VQL K;  2ZJQ H;  1K73 L;  1VQ9 K;  1VQP K;  1M1K L;  1NJI L;  5JVH H;  1KQS J;  3CXC J;  2QEX K;  3CCJ K;  2ZJR H;  3CC2 K;  3CCR K;  3G71 K;  1VQN K;  3J7Z K;  5GAE L;  1VQO K;  1VQ6 K;  3CCS K;  4V19 O;  4WFB H;  1YJW K;  1YJ9 K;  3CPW J;  5DM6 H;  1VQ4 K;  1KC8 L;  3CC4 K;  1Q81 L;  1YI2 K;  2OTL K;  4WF9 H;  3PIO H;  3CCM K;  3CCU K;  4IO9 H;  1QVG J;  1M90 L;  3J7Y L;  5AN9 E;  5H1S M;  3CD6 K;  5MLC M;  3G6E K;  4WCE H;  3CF5 H;  5JVG H;  3CCE K;  3CMA K;  3I56 K;  3CC7 K;  5GAD L;  4WFN H;  5GAH L;  1Q7Y L;  1Q86 L;  1JJ2 J;  1VQK K;  1W2B J;  1YJN K;  1S72 K;  3G4S K;  3OW2 J;  1K8A L;  4IOC H;  4IOA H;  3I55 K;  4UY8 K;  1QVF J;  5HL7 H;  2ZJP H;  1YIT K;  1N8R L;  5GAG L;  5DM7 H;  1WHI A;  1YIJ K;  2OTJ K;  1VQ5 K;  2QA4 K;  4WFA H;  4U67 H;  3DLL H;  3CME K;  1VQM K; 
#chains in the Genus database with same CATH topology
 3CCQ K;  3PIP H;  1K9M L;  1VQ7 K;  1VQ8 K;  1KD1 L;  1Q82 L;  3CCL K;  1YHQ K;  3CCV K;  1VQL K;  2ZJQ H;  1K73 L;  1VQ9 K;  1VQP K;  1M1K L;  1NJI L;  5JVH H;  1KQS J;  3CXC J;  2QEX K;  3CCJ K;  2ZJR H;  3CC2 K;  3CCR K;  3G71 K;  1VQN K;  3J7Z K;  5GAE L;  1VQO K;  1VQ6 K;  3CCS K;  4V19 O;  4WFB H;  1YJW K;  1YJ9 K;  3CPW J;  5DM6 H;  1VQ4 K;  1KC8 L;  3CC4 K;  1Q81 L;  1YI2 K;  2OTL K;  4WF9 H;  3PIO H;  3CCM K;  3CCU K;  4IO9 H;  1QVG J;  1M90 L;  3J7Y L;  5AN9 E;  5H1S M;  3CD6 K;  5MLC M;  3G6E K;  4WCE H;  3CF5 H;  5JVG H;  3CCE K;  3CMA K;  3I56 K;  3CC7 K;  5GAD L;  4WFN H;  5GAH L;  1Q7Y L;  1Q86 L;  1JJ2 J;  1VQK K;  1W2B J;  1YJN K;  1S72 K;  3G4S K;  3OW2 J;  1K8A L;  4IOC H;  4IOA H;  3I55 K;  4UY8 K;  1QVF J;  5HL7 H;  2ZJP H;  1YIT K;  1N8R L;  5GAG L;  5DM7 H;  1WHI A;  1YIJ K;  2OTJ K;  1VQ5 K;  2QA4 K;  4WFA H;  4U67 H;  3DLL H;  3CME K;  1VQM K; 
#chains in the Genus database with same CATH homology
 3CCQ K;  3PIP H;  1K9M L;  1VQ7 K;  1VQ8 K;  1KD1 L;  1Q82 L;  3CCL K;  1YHQ K;  3CCV K;  1VQL K;  2ZJQ H;  1K73 L;  1VQ9 K;  1VQP K;  1M1K L;  1NJI L;  5JVH H;  1KQS J;  3CXC J;  2QEX K;  3CCJ K;  2ZJR H;  3CC2 K;  3CCR K;  3G71 K;  1VQN K;  3J7Z K;  5GAE L;  1VQO K;  1VQ6 K;  3CCS K;  4V19 O;  4WFB H;  1YJW K;  1YJ9 K;  3CPW J;  5DM6 H;  1VQ4 K;  1KC8 L;  3CC4 K;  1Q81 L;  1YI2 K;  2OTL K;  4WF9 H;  3PIO H;  3CCM K;  3CCU K;  4IO9 H;  1QVG J;  1M90 L;  3J7Y L;  5AN9 E;  5H1S M;  3CD6 K;  5MLC M;  3G6E K;  4WCE H;  3CF5 H;  5JVG H;  3CCE K;  3CMA K;  3I56 K;  3CC7 K;  5GAD L;  4WFN H;  5GAH L;  1Q7Y L;  1Q86 L;  1JJ2 J;  1VQK K;  1W2B J;  1YJN K;  1S72 K;  3G4S K;  3OW2 J;  1K8A L;  4IOC H;  4IOA H;  3I55 K;  4UY8 K;  1QVF J;  5HL7 H;  2ZJP H;  1YIT K;  1N8R L;  5GAG L;  5DM7 H;  1WHI A;  1YIJ K;  2OTJ K;  1VQ5 K;  2QA4 K;  4WFA H;  4U67 H;  3DLL H;  3CME K;  1VQM K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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