3CCVK

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
132
structure length
132
Chain Sequence
MEALGADVTQGLEKGSLITCADNTGARELKVISVHGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAQRFGSVASAATMIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 29
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 3ccvK00
5HL7H 1NJIL 1K9ML 3CXCJ 1Q7YL 2OTLK 5DM6H 3PIOH 1VQ7K 1YIJK 3PIPH 2QEXK 4WCEH 1VQLK 4WFBH 1YJNK 3CCLK 1K8AL 3J7YL 5GAEL 2ZJPH 5GAHL 1VQMK 5GADL 2OTJK 3I56K 4WF9H 1YJWK 4U67H 1JJ2J 3CMAK 1KQSJ 1VQKK 3CMEK 4IO9H 4WFAH 3CC2K 1S72K 1VQPK 1VQ8K 3G71K 4IOAH 1VQNK 3CCUK 1KC8L 5H1SM 1KD1L 3J7ZK 1VQ5K 5DM7H 1Q86L 3CCJK 5AN9E 4V19O 1YHQK 4WFNH 5JVHH 1YITK 1YI2K 3G6EK 1K73L 1M1KL 3CCQK 1Q81L 3DLLH 1VQOK 1M90L 3CC4K 3CCEK 1VQ4K 5JVGH 3G4SK 3OW2J 1VQ9K 1N8RL 4UY8K 3CC7K 3CPWJ 2ZJRH 3CCVK 1WHIA 3CF5H 3I55K 4IOCH 3CCRK 1QVFJ 5MLCM 1VQ6K 3CCMK 2QA4K 3CD6K 1YJ9K 1W2BJ 5GAGL 2ZJQH 3CCSK 1QVGJ 1Q82L
chains in the Genus database with same CATH superfamily
5HL7H 1NJIL 1K9ML 3CXCJ 1Q7YL 2OTLK 5DM6H 3PIOH 1VQ7K 1YIJK 3PIPH 2QEXK 4WCEH 1VQLK 4WFBH 1YJNK 3CCLK 1K8AL 3J7YL 5GAEL 2ZJPH 5GAHL 1VQMK 5GADL 2OTJK 3I56K 4WF9H 1YJWK 4U67H 1JJ2J 3CMAK 1KQSJ 1VQKK 3CMEK 4IO9H 4WFAH 3CC2K 1S72K 1VQPK 1VQ8K 3G71K 4IOAH 1VQNK 3CCUK 1KC8L 5H1SM 1KD1L 3J7ZK 1VQ5K 5DM7H 1Q86L 3CCJK 5AN9E 4V19O 1YHQK 4WFNH 5JVHH 1YITK 1YI2K 3G6EK 1K73L 1M1KL 3CCQK 1Q81L 3DLLH 1VQOK 1M90L 3CC4K 3CCEK 1VQ4K 5JVGH 3G4SK 3OW2J 1VQ9K 1N8RL 4UY8K 3CC7K 3CPWJ 2ZJRH 3CCVK 1WHIA 3CF5H 3I55K 4IOCH 3CCRK 1QVFJ 5MLCM 1VQ6K 3CCMK 2QA4K 3CD6K 1YJ9K 1W2BJ 5GAGL 2ZJQH 3CCSK 1QVGJ 1Q82L
chains in the Genus database with same CATH topology
5HL7H 1NJIL 1K9ML 3CXCJ 1Q7YL 2OTLK 5DM6H 3PIOH 1VQ7K 1YIJK 3PIPH 2QEXK 4WCEH 1VQLK 4WFBH 1YJNK 3CCLK 1K8AL 3J7YL 5GAEL 2ZJPH 5GAHL 1VQMK 5GADL 2OTJK 3I56K 4WF9H 1YJWK 4U67H 1JJ2J 3CMAK 1KQSJ 1VQKK 3CMEK 4IO9H 4WFAH 3CC2K 1S72K 1VQPK 1VQ8K 3G71K 4IOAH 1VQNK 3CCUK 1KC8L 5H1SM 1KD1L 3J7ZK 1VQ5K 5DM7H 1Q86L 3CCJK 5AN9E 4V19O 1YHQK 4WFNH 5JVHH 1YITK 1YI2K 3G6EK 1K73L 1M1KL 3CCQK 1Q81L 3DLLH 1VQOK 1M90L 3CC4K 3CCEK 1VQ4K 5JVGH 3G4SK 3OW2J 1VQ9K 1N8RL 4UY8K 3CC7K 3CPWJ 2ZJRH 3CCVK 1WHIA 3CF5H 3I55K 4IOCH 3CCRK 1QVFJ 5MLCM 1VQ6K 3CCMK 2QA4K 3CD6K 1YJ9K 1W2BJ 5GAGL 2ZJQH 3CCSK 1QVGJ 1Q82L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HL7 H;  1NJI L;  1K9M L;  3CXC J;  1Q7Y L;  2OTL K;  5DM6 H;  3PIO H;  1VQ7 K;  1YIJ K;  3PIP H;  2QEX K;  4WCE H;  1VQL K;  4WFB H;  1YJN K;  3CCL K;  1K8A L;  3J7Y L;  5GAE L;  2ZJP H;  5GAH L;  1VQM K;  5GAD L;  2OTJ K;  3I56 K;  4WF9 H;  1YJW K;  4U67 H;  1JJ2 J;  3CMA K;  1KQS J;  1VQK K;  3CME K;  4IO9 H;  4WFA H;  3CC2 K;  1S72 K;  1VQP K;  1VQ8 K;  3G71 K;  4IOA H;  1VQN K;  3CCU K;  1KC8 L;  5H1S M;  1KD1 L;  3J7Z K;  1VQ5 K;  5DM7 H;  1Q86 L;  3CCJ K;  5AN9 E;  4V19 O;  1YHQ K;  4WFN H;  5JVH H;  1YIT K;  1YI2 K;  3G6E K;  1K73 L;  1M1K L;  3CCQ K;  1Q81 L;  3DLL H;  1VQO K;  1M90 L;  3CC4 K;  3CCE K;  1VQ4 K;  5JVG H;  3G4S K;  3OW2 J;  1VQ9 K;  1N8R L;  4UY8 K;  3CC7 K;  3CPW J;  2ZJR H;  3CCV K;  1WHI A;  3CF5 H;  3I55 K;  4IOC H;  3CCR K;  1QVF J;  5MLC M;  1VQ6 K;  3CCM K;  2QA4 K;  3CD6 K;  1YJ9 K;  1W2B J;  5GAG L;  2ZJQ H;  3CCS K;  1QVG J;  1Q82 L; 
#chains in the Genus database with same CATH topology
 5HL7 H;  1NJI L;  1K9M L;  3CXC J;  1Q7Y L;  2OTL K;  5DM6 H;  3PIO H;  1VQ7 K;  1YIJ K;  3PIP H;  2QEX K;  4WCE H;  1VQL K;  4WFB H;  1YJN K;  3CCL K;  1K8A L;  3J7Y L;  5GAE L;  2ZJP H;  5GAH L;  1VQM K;  5GAD L;  2OTJ K;  3I56 K;  4WF9 H;  1YJW K;  4U67 H;  1JJ2 J;  3CMA K;  1KQS J;  1VQK K;  3CME K;  4IO9 H;  4WFA H;  3CC2 K;  1S72 K;  1VQP K;  1VQ8 K;  3G71 K;  4IOA H;  1VQN K;  3CCU K;  1KC8 L;  5H1S M;  1KD1 L;  3J7Z K;  1VQ5 K;  5DM7 H;  1Q86 L;  3CCJ K;  5AN9 E;  4V19 O;  1YHQ K;  4WFN H;  5JVH H;  1YIT K;  1YI2 K;  3G6E K;  1K73 L;  1M1K L;  3CCQ K;  1Q81 L;  3DLL H;  1VQO K;  1M90 L;  3CC4 K;  3CCE K;  1VQ4 K;  5JVG H;  3G4S K;  3OW2 J;  1VQ9 K;  1N8R L;  4UY8 K;  3CC7 K;  3CPW J;  2ZJR H;  3CCV K;  1WHI A;  3CF5 H;  3I55 K;  4IOC H;  3CCR K;  1QVF J;  5MLC M;  1VQ6 K;  3CCM K;  2QA4 K;  3CD6 K;  1YJ9 K;  1W2B J;  5GAG L;  2ZJQ H;  3CCS K;  1QVG J;  1Q82 L; 
#chains in the Genus database with same CATH homology
 5HL7 H;  1NJI L;  1K9M L;  3CXC J;  1Q7Y L;  2OTL K;  5DM6 H;  3PIO H;  1VQ7 K;  1YIJ K;  3PIP H;  2QEX K;  4WCE H;  1VQL K;  4WFB H;  1YJN K;  3CCL K;  1K8A L;  3J7Y L;  5GAE L;  2ZJP H;  5GAH L;  1VQM K;  5GAD L;  2OTJ K;  3I56 K;  4WF9 H;  1YJW K;  4U67 H;  1JJ2 J;  3CMA K;  1KQS J;  1VQK K;  3CME K;  4IO9 H;  4WFA H;  3CC2 K;  1S72 K;  1VQP K;  1VQ8 K;  3G71 K;  4IOA H;  1VQN K;  3CCU K;  1KC8 L;  5H1S M;  1KD1 L;  3J7Z K;  1VQ5 K;  5DM7 H;  1Q86 L;  3CCJ K;  5AN9 E;  4V19 O;  1YHQ K;  4WFN H;  5JVH H;  1YIT K;  1YI2 K;  3G6E K;  1K73 L;  1M1K L;  3CCQ K;  1Q81 L;  3DLL H;  1VQO K;  1M90 L;  3CC4 K;  3CCE K;  1VQ4 K;  5JVG H;  3G4S K;  3OW2 J;  1VQ9 K;  1N8R L;  4UY8 K;  3CC7 K;  3CPW J;  2ZJR H;  3CCV K;  1WHI A;  3CF5 H;  3I55 K;  4IOC H;  3CCR K;  1QVF J;  5MLC M;  1VQ6 K;  3CCM K;  2QA4 K;  3CD6 K;  1YJ9 K;  1W2B J;  5GAG L;  2ZJQ H;  3CCS K;  1QVG J;  1Q82 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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