3SM4A

Crystal structure of the k131a mutant of lambda exonuclease in complex with a 5'-phosphorylated 14-mer/12-mer duplex and magnesium
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
225
structure length
225
Chain Sequence
TPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELACPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKNAWYFANYDPRMKREGLHYVVIERDEKYMASFDEIVPEFIEKMDEALAEIGFVFGEQWR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Enterobacteria phage lambda
molecule keywords Exonuclease
total genus 66
structure length 225
sequence length 225
chains with identical sequence B, C
ec nomenclature ec 3.1.11.3: Exodeoxyribonuclease (lambda-induced).
pdb deposition date 2011-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09588 YqaJ YqaJ-like viral recombinase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.320.10 Alpha Beta Alpha-Beta Complex Lambda Exonuclease; Chain A Lambda Exonuclease; Chain A 3sm4A00
1W36B 4WUZA 3K70B 3SZ5A 1AVQA 4CEIA 3H4RA 3U44A 3U4QA 3SZ4A 5LD2B 4CEHA 3K93A 3L0AA 3SYYA 3SLPA 4CEJA 4R5QA 3SM4A 4IC1A
chains in the Genus database with same CATH superfamily
1W36B 4WUZA 3K70B 3POTC 5A8WC 3SQGC 5A8RC 1AVQA 3SZ5A 4CEIA 3H4RA 3U44A 3M2UC 1HBNC 1E6YC 5G0RC 3U4QA 1MROC 3SZ4A 5LD2B 5A8KC 3M2RC 3M1VC 3M32C 1HBMC 1HBUC 5A0YC 4CEHA 3K93A 1HBOC 3L0AA 3SYYA 3SLPA 4CEJA 3M30C 3M2VC 4R5QA 1E6VC 3SM4A 4IC1A
chains in the Genus database with same CATH topology
1W36B 4WUZA 3K70B 3SZ5A 1AVQA 4CEIA 3H4RA 3U44A 3U4QA 3SZ4A 5LD2B 4CEHA 3K93A 3L0AA 3SYYA 3SLPA 4CEJA 4R5QA 3SM4A 4IC1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W36 B;  4WUZ A;  3K70 B;  3SZ5 A;  1AVQ A;  4CEI A;  3H4R A;  3U44 A;  3U4Q A;  3SZ4 A;  5LD2 B;  4CEH A;  3K93 A;  3L0A A;  3SYY A;  3SLP A;  4CEJ A;  4R5Q A;  3SM4 A;  4IC1 A; 
#chains in the Genus database with same CATH topology
 1W36 B;  4WUZ A;  3K70 B;  3POT C;  5A8W C;  3SQG C;  5A8R C;  1AVQ A;  3SZ5 A;  4CEI A;  3H4R A;  3U44 A;  3M2U C;  1HBN C;  1E6Y C;  5G0R C;  3U4Q A;  1MRO C;  3SZ4 A;  5LD2 B;  5A8K C;  3M2R C;  3M1V C;  3M32 C;  1HBM C;  1HBU C;  5A0Y C;  4CEH A;  3K93 A;  1HBO C;  3L0A A;  3SYY A;  3SLP A;  4CEJ A;  3M30 C;  3M2V C;  4R5Q A;  1E6V C;  3SM4 A;  4IC1 A; 
#chains in the Genus database with same CATH homology
 1W36 B;  4WUZ A;  3K70 B;  3SZ5 A;  1AVQ A;  4CEI A;  3H4R A;  3U44 A;  3U4Q A;  3SZ4 A;  5LD2 B;  4CEH A;  3K93 A;  3L0A A;  3SYY A;  3SLP A;  4CEJ A;  4R5Q A;  3SM4 A;  4IC1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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