4E2TA

Crystal structures of rada intein from pyrococcus horikoshii
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
172
structure length
172
Chain Sequence
AFARDTEVYYENDTVPHMESIEEMYSKYASMNGELPFDNGYAVPLDNVFVYTLDIASGEIKKTRASYIYREKVEKLIEIKLSSGYSLKVTPSHPVLLFRDGLQWVPAAEVKPGDVVVGVREEVLRRRIISKGELEFHEVSSVRIIDYNNWVYDLVIPETHNFIAPNGLVLHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein.
pubmed doi rcsb
molecule tags Unknown function
source organism Pyrococcus horikoshii
molecule keywords Pho radA intein
total genus 42
structure length 172
sequence length 172
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14890 Intein_splicing Intein splicing domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.16.10 Mainly Beta Beta Complex Endonuclease - Pi-scei; Chain A, domain 1 Hedgehog/Intein (Hint) domain 4e2tA00
3IGDA 1UM2A 5K08A 1VDEA 2LCJA 4OZ6A 2IN8A 2KEQA 1ZDEA 1LWSA 1JVAA 1ZD7A 3NZMA 4KL6A 2CW8A 2LWYA 1LWTA 2IN9A 4E2TA 4E2UA 2IMZA 1GPPA 2L8LA 2LQMA 2CW7A 1AT0A 4O1SA 2IN0A 4KL5A 2JMZA 3IFJA 2JNQA 4O1RA 1DQ3A 1MI8A 4GIGA 1DFAA 1AM2A 1EF0A 5I0AA
chains in the Genus database with same CATH superfamily
3IGDA 1UM2A 5K08A 1VDEA 2LCJA 4OZ6A 2IN8A 2KEQA 4QFQA 1ZDEA 1LWSA 1JVAA 1ZD7A 4LX3A 3NZMA 4KL6A 2CW8A 2LWYA 1LWTA 2IN9A 4E2TA 4E2UA 2IMZA 1GPPA 2L8LA 2LQMA 2CW7A 1AT0A 4O1SA 2IN0A 4KL5A 2JMZA 3IFJA 2JNQA 4O1RA 1DQ3A 1MI8A 4GIGA 1DFAA 1AM2A 1EF0A 5I0AA
chains in the Genus database with same CATH topology
3IGDA 1UM2A 5K08A 1VDEA 2LCJA 4OZ6A 2IN8A 2KEQA 1ZDEA 1LWSA 1JVAA 1ZD7A 3NZMA 4KL6A 2CW8A 2LWYA 1LWTA 2IN9A 4E2TA 4E2UA 2IMZA 1GPPA 2L8LA 2LQMA 2CW7A 1AT0A 4O1SA 2IN0A 4KL5A 2JMZA 3IFJA 2JNQA 4O1RA 1DQ3A 1MI8A 4GIGA 1DFAA 1AM2A 1EF0A 5I0AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IGD A;  1UM2 A;  5K08 A;  1VDE A;  2LCJ A;  4OZ6 A;  2IN8 A;  2KEQ A;  1ZDE A;  1LWS A;  1JVA A;  1ZD7 A;  3NZM A;  4KL6 A;  2CW8 A;  2LWY A;  1LWT A;  2IN9 A;  4E2T A;  4E2U A;  2IMZ A;  1GPP A;  2L8L A;  2LQM A;  2CW7 A;  1AT0 A;  4O1S A;  2IN0 A;  4KL5 A;  2JMZ A;  3IFJ A;  2JNQ A;  4O1R A;  1DQ3 A;  1MI8 A;  4GIG A;  1DFA A;  1AM2 A;  1EF0 A;  5I0A A; 
#chains in the Genus database with same CATH topology
 3IGD A;  1UM2 A;  5K08 A;  1VDE A;  2LCJ A;  4OZ6 A;  2IN8 A;  2KEQ A;  4QFQ A;  1ZDE A;  1LWS A;  1JVA A;  1ZD7 A;  4LX3 A;  3NZM A;  4KL6 A;  2CW8 A;  2LWY A;  1LWT A;  2IN9 A;  4E2T A;  4E2U A;  2IMZ A;  1GPP A;  2L8L A;  2LQM A;  2CW7 A;  1AT0 A;  4O1S A;  2IN0 A;  4KL5 A;  2JMZ A;  3IFJ A;  2JNQ A;  4O1R A;  1DQ3 A;  1MI8 A;  4GIG A;  1DFA A;  1AM2 A;  1EF0 A;  5I0A A; 
#chains in the Genus database with same CATH homology
 3IGD A;  1UM2 A;  5K08 A;  1VDE A;  2LCJ A;  4OZ6 A;  2IN8 A;  2KEQ A;  1ZDE A;  1LWS A;  1JVA A;  1ZD7 A;  3NZM A;  4KL6 A;  2CW8 A;  2LWY A;  1LWT A;  2IN9 A;  4E2T A;  4E2U A;  2IMZ A;  1GPP A;  2L8L A;  2LQM A;  2CW7 A;  1AT0 A;  4O1S A;  2IN0 A;  4KL5 A;  2JMZ A;  3IFJ A;  2JNQ A;  4O1R A;  1DQ3 A;  1MI8 A;  4GIG A;  1DFA A;  1AM2 A;  1EF0 A;  5I0A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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