4E2U | Genus

Total Genus 41

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	41
sequence length	168
structure length	168
Chain Sequence	SQHMAFARDTEVYYENDTVPHMESIEEMYSKYASMNGELPFDNGYAVPLDNVFVYTLDIASGEIKKTRASYIYREKVEKLIEIKLSSGYSLKVTPSHPVLLFRDGLQWVPAAEVKPGDVVVGVRNGELEFHEVSSVRIIDYNNWVYDLVIPETHNFIAPNGLVLHNAQ

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Unknown function
source organism	Pyrococcus horikoshii
publication title	NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein. pubmed doi rcsb
molecule keywords	Pho radA intein
total genus	41
structure length	168
sequence length	168
ec nomenclature
pdb deposition date	2012-03-09

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF14890	Intein_splicing	Intein splicing domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.170.16.10	Mainly Beta	Beta Complex	Endonuclease - Pi-scei; Chain A, domain 1	Hedgehog/Intein (Hint) domain	4e2uA00

1EF0A 2CW8A 1ZDEA 2IN0A 3IFJA 1JVAA 4O1RA 4OZ6A 4GIGA 2IMZA 2CW7A 1LWSA 1UM2A 1AM2A 4E2UA 2LWYA 1DQ3A 3NZMA 1ZD7A 1MI8A 2JNQA 1AT0A 1GPPA 4O1SA 4E2TA 4KL6A 2JMZA 2LQMA 2L8LA 5K08A 2IN8A 3IGDA 2LCJA 1LWTA 2KEQA 5I0AA 4KL5A 1DFAA 2IN9A 1VDEA
chains in the Genus database with same CATH superfamily

1EF0A 4LX3A 2CW8A 1ZDEA 2IN0A 3IFJA 1JVAA 4O1RA 4OZ6A 4GIGA 2IMZA 2CW7A 1LWSA 1UM2A 1AM2A 4QFQA 4E2UA 2LWYA 1DQ3A 3NZMA 1ZD7A 1MI8A 2JNQA 1AT0A 1GPPA 4O1SA 4E2TA 4KL6A 2JMZA 2LQMA 2L8LA 5K08A 2IN8A 3IGDA 2LCJA 1LWTA 2KEQA 5I0AA 4KL5A 1DFAA 2IN9A 1VDEA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1EF0 A;  2CW8 A;  1ZDE A;  2IN0 A;  3IFJ A;  1JVA A;  4O1R A;  4OZ6 A;  4GIG A;  2IMZ A;  2CW7 A;  1LWS A;  1UM2 A;  1AM2 A;  4E2U A;  2LWY A;  1DQ3 A;  3NZM A;  1ZD7 A;  1MI8 A;  2JNQ A;  1AT0 A;  1GPP A;  4O1S A;  4E2T A;  4KL6 A;  2JMZ A;  2LQM A;  2L8L A;  5K08 A;  2IN8 A;  3IGD A;  2LCJ A;  1LWT A;  2KEQ A;  5I0A A;  4KL5 A;  1DFA A;  2IN9 A;  1VDE A; 
#chains in the Genus database with same CATH topology
 1EF0 A;  4LX3 A;  2CW8 A;  1ZDE A;  2IN0 A;  3IFJ A;  1JVA A;  4O1R A;  4OZ6 A;  4GIG A;  2IMZ A;  2CW7 A;  1LWS A;  1UM2 A;  1AM2 A;  4QFQ A;  4E2U A;  2LWY A;  1DQ3 A;  3NZM A;  1ZD7 A;  1MI8 A;  2JNQ A;  1AT0 A;  1GPP A;  4O1S A;  4E2T A;  4KL6 A;  2JMZ A;  2LQM A;  2L8L A;  5K08 A;  2IN8 A;  3IGD A;  2LCJ A;  1LWT A;  2KEQ A;  5I0A A;  4KL5 A;  1DFA A;  2IN9 A;  1VDE A; 
#chains in the Genus database with same CATH homology
 1EF0 A;  2CW8 A;  1ZDE A;  2IN0 A;  3IFJ A;  1JVA A;  4O1R A;  4OZ6 A;  4GIG A;  2IMZ A;  2CW7 A;  1LWS A;  1UM2 A;  1AM2 A;  4E2U A;  2LWY A;  1DQ3 A;  3NZM A;  1ZD7 A;  1MI8 A;  2JNQ A;  1AT0 A;  1GPP A;  4O1S A;  4E2T A;  4KL6 A;  2JMZ A;  2LQM A;  2L8L A;  5K08 A;  2IN8 A;  3IGD A;  2LCJ A;  1LWT A;  2KEQ A;  5I0A A;  4KL5 A;  1DFA A;  2IN9 A;  1VDE A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4E2UA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations