4ENEA

Structure of the n- and c-terminal trimmed clc-ec1 cl-/h+ antiporter and fab complex
Total Genus 185
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
185
sequence length
444
structure length
444
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Intracellular proton access in a cl(-)/h(+) antiporter.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli k-12
molecule keywords H(+)/Cl(-) exchange transporter ClcA
total genus 185
structure length 444
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 4eneA00
4FG6A 4KK5A 4ENEA 4KJWA 3Q17A 2HTKA 2EZ0A 2HT2A 1KPLA 2HT3A 4KKCA 4KK6A 4KK8A 3DETA 2HLFA 4KKLA 2HT4A 4KKBA 1OTSA 1OTTA 2R9HA 4KJQA 1KPKA 1OTUA 3EJYA 3NMOA 4FTPA 3ORGA 2H2PA 2EXYA 3EJZA 2HTLA 2FECA 4MQXA 4KK9A 4KJPA 2FEEA 2H2SA 4KKAA 5HD8A 2EXWA 2FEDA 4LOUA 3ND0A
chains in the Genus database with same CATH superfamily
4FG6A 4KK5A 4ENEA 4KJWA 3Q17A 2HTKA 2EZ0A 2HT2A 1KPLA 2HT3A 4KKCA 4KK6A 4KK8A 3DETA 2HLFA 4KKLA 2HT4A 4KKBA 1OTSA 1OTTA 2R9HA 4KJQA 1KPKA 1OTUA 3EJYA 3NMOA 4FTPA 3ORGA 2H2PA 2EXYA 3EJZA 2HTLA 2FECA 4MQXA 4KK9A 4KJPA 2FEEA 2H2SA 4KKAA 5HD8A 2EXWA 2FEDA 4LOUA 3ND0A
chains in the Genus database with same CATH topology
4FG6A 4KK5A 4ENEA 4KJWA 3Q17A 2HTKA 2EZ0A 2HT2A 1KPLA 2HT3A 4KKCA 4KK6A 4KK8A 3DETA 2HLFA 4KKLA 2HT4A 4KKBA 1OTSA 1OTTA 2R9HA 4KJQA 1KPKA 1OTUA 3EJYA 3NMOA 4FTPA 3ORGA 2H2PA 2EXYA 3EJZA 2HTLA 2FECA 4MQXA 4KK9A 4KJPA 2FEEA 2H2SA 4KKAA 5HD8A 2EXWA 2FEDA 4LOUA 3ND0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FG6 A;  4KK5 A;  4ENE A;  4KJW A;  3Q17 A;  2HTK A;  2EZ0 A;  2HT2 A;  1KPL A;  2HT3 A;  4KKC A;  4KK6 A;  4KK8 A;  3DET A;  2HLF A;  4KKL A;  2HT4 A;  4KKB A;  1OTS A;  1OTT A;  2R9H A;  4KJQ A;  1KPK A;  1OTU A;  3EJY A;  3NMO A;  4FTP A;  3ORG A;  2H2P A;  2EXY A;  3EJZ A;  2HTL A;  2FEC A;  4MQX A;  4KK9 A;  4KJP A;  2FEE A;  2H2S A;  4KKA A;  5HD8 A;  2EXW A;  2FED A;  4LOU A;  3ND0 A; 
#chains in the Genus database with same CATH topology
 4FG6 A;  4KK5 A;  4ENE A;  4KJW A;  3Q17 A;  2HTK A;  2EZ0 A;  2HT2 A;  1KPL A;  2HT3 A;  4KKC A;  4KK6 A;  4KK8 A;  3DET A;  2HLF A;  4KKL A;  2HT4 A;  4KKB A;  1OTS A;  1OTT A;  2R9H A;  4KJQ A;  1KPK A;  1OTU A;  3EJY A;  3NMO A;  4FTP A;  3ORG A;  2H2P A;  2EXY A;  3EJZ A;  2HTL A;  2FEC A;  4MQX A;  4KK9 A;  4KJP A;  2FEE A;  2H2S A;  4KKA A;  5HD8 A;  2EXW A;  2FED A;  4LOU A;  3ND0 A; 
#chains in the Genus database with same CATH homology
 4FG6 A;  4KK5 A;  4ENE A;  4KJW A;  3Q17 A;  2HTK A;  2EZ0 A;  2HT2 A;  1KPL A;  2HT3 A;  4KKC A;  4KK6 A;  4KK8 A;  3DET A;  2HLF A;  4KKL A;  2HT4 A;  4KKB A;  1OTS A;  1OTT A;  2R9H A;  4KJQ A;  1KPK A;  1OTU A;  3EJY A;  3NMO A;  4FTP A;  3ORG A;  2H2P A;  2EXY A;  3EJZ A;  2HTL A;  2FEC A;  4MQX A;  4KK9 A;  4KJP A;  2FEE A;  2H2S A;  4KKA A;  5HD8 A;  2EXW A;  2FED A;  4LOU A;  3ND0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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