4EUWA

Crystal structure of a hmg domain of transcription factor sox-9 bound to dna (sox-9/dna) from homo sapiens at 2.77 a resolution
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
72
structure length
72
Chain Sequence
PHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of a HMG domain of transcription factor SOX-9 bound to DNA (SOX-9/DNA) from Homo sapiens at 2.77 A resolution
rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords Transcription factor SOX-9
total genus 22
structure length 72
sequence length 72
ec nomenclature
pdb deposition date 2012-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00505 HMG_box HMG (high mobility group) box
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 4euwA00
1HSNA 1V63A 1WGFA 1O4XB 1WZ6A 3TMMA 2EQZA 1QRVA 1I11A 2HDZA 4Y60C 1CKTA 2CO9A 2YRQA 1LWMA 4NODA 2LHJA 1HMFA 4QR9A 1J46A 1NHMA 1V64A 1J5NA 2LY4A 2LEFA 3NM9A 3F27D 1GT0D 3TQ6A 1L8ZA 1E7JA 1HRYA 4NNUA 1WXLA 1L8YA 2D7LA 1J3CA 1J3XA 2CRJA 4S2QD 1HMEA 2YUKA 2GZKA 3U2BC 2YQIA 2LE4A 4EUWA 2CTOA 1CG7A 1J3DA 1K99A 4A3NA 2YULA 3FGHA 1HRZA 1J47A 1AABA 1NHNA 2RTUA 1HMAA 2E6OA 2CS1A 1HSMA
chains in the Genus database with same CATH superfamily
1J3XA 1HSNA 1V63A 1WGFA 4KQEA 1O4XB 1WZ6A 3TMMA 5H8WA 2EQZA 1QRVA 1I11A 2HDZA 4Y60C 1CKTA 2CO9A 2YRQA 1LWMA 3ABOB 2LHJA 3ANYB 4QR9A 4NODA 1HMFA 1J46A 2VSFA 1NHMA 1V64A 1J5NA 2LY4A 4A15A 3NM9A 3F27D 1GT0D 3TQ6A 1L8ZA 1E7JA 1HRYA 4NNUA 1WXLA 1L8YA 2D7LA 3ABSB 3AO0B 2CRJA 4S2QD 2LEFA 1J3CA 1HMEA 2YUKA 2GZKA 3U2BC 2YQIA 2LE4A 4EUWA 2CTOA 1CG7A 1J3DA 1K99A 4A3NA 2YULA 3FGHA 1HRZA 1J47A 1AABA 1NHNA 2RTUA 1HMAA 2E6OA 2CS1A 3ABRB 1HSMA
chains in the Genus database with same CATH topology
1HSNA 1V63A 1WGFA 1O4XB 1WZ6A 3TMMA 2EQZA 1QRVA 1I11A 2HDZA 4Y60C 1CKTA 2CO9A 2YRQA 1LWMA 4NODA 2LHJA 1HMFA 4QR9A 1J46A 1NHMA 1V64A 1J5NA 2LY4A 2LEFA 3NM9A 3F27D 1GT0D 3TQ6A 1L8ZA 1E7JA 1HRYA 4NNUA 1WXLA 1L8YA 2D7LA 1J3CA 1J3XA 2CRJA 4S2QD 1HMEA 2YUKA 2GZKA 3U2BC 2YQIA 2LE4A 4EUWA 2CTOA 1CG7A 1J3DA 1K99A 4A3NA 2YULA 3FGHA 1HRZA 1J47A 1AABA 1NHNA 2RTUA 1HMAA 2E6OA 2CS1A 1HSMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HSN A;  1V63 A;  1WGF A;  1O4X B;  1WZ6 A;  3TMM A;  2EQZ A;  1QRV A;  1I11 A;  2HDZ A;  4Y60 C;  1CKT A;  2CO9 A;  2YRQ A;  1LWM A;  4NOD A;  2LHJ A;  1HMF A;  4QR9 A;  1J46 A;  1NHM A;  1V64 A;  1J5N A;  2LY4 A;  2LEF A;  3NM9 A;  3F27 D;  1GT0 D;  3TQ6 A;  1L8Z A;  1E7J A;  1HRY A;  4NNU A;  1WXL A;  1L8Y A;  2D7L A;  1J3C A;  1J3X A;  2CRJ A;  4S2Q D;  1HME A;  2YUK A;  2GZK A;  3U2B C;  2YQI A;  2LE4 A;  4EUW A;  2CTO A;  1CG7 A;  1J3D A;  1K99 A;  4A3N A;  2YUL A;  3FGH A;  1HRZ A;  1J47 A;  1AAB A;  1NHN A;  2RTU A;  1HMA A;  2E6O A;  2CS1 A;  1HSM A; 
#chains in the Genus database with same CATH topology
 1J3X A;  1HSN A;  1V63 A;  1WGF A;  4KQE A;  1O4X B;  1WZ6 A;  3TMM A;  5H8W A;  2EQZ A;  1QRV A;  1I11 A;  2HDZ A;  4Y60 C;  1CKT A;  2CO9 A;  2YRQ A;  1LWM A;  3ABO B;  2LHJ A;  3ANY B;  4QR9 A;  4NOD A;  1HMF A;  1J46 A;  2VSF A;  1NHM A;  1V64 A;  1J5N A;  2LY4 A;  4A15 A;  3NM9 A;  3F27 D;  1GT0 D;  3TQ6 A;  1L8Z A;  1E7J A;  1HRY A;  4NNU A;  1WXL A;  1L8Y A;  2D7L A;  3ABS B;  3AO0 B;  2CRJ A;  4S2Q D;  2LEF A;  1J3C A;  1HME A;  2YUK A;  2GZK A;  3U2B C;  2YQI A;  2LE4 A;  4EUW A;  2CTO A;  1CG7 A;  1J3D A;  1K99 A;  4A3N A;  2YUL A;  3FGH A;  1HRZ A;  1J47 A;  1AAB A;  1NHN A;  2RTU A;  1HMA A;  2E6O A;  2CS1 A;  3ABR B;  1HSM A; 
#chains in the Genus database with same CATH homology
 1HSN A;  1V63 A;  1WGF A;  1O4X B;  1WZ6 A;  3TMM A;  2EQZ A;  1QRV A;  1I11 A;  2HDZ A;  4Y60 C;  1CKT A;  2CO9 A;  2YRQ A;  1LWM A;  4NOD A;  2LHJ A;  1HMF A;  4QR9 A;  1J46 A;  1NHM A;  1V64 A;  1J5N A;  2LY4 A;  2LEF A;  3NM9 A;  3F27 D;  1GT0 D;  3TQ6 A;  1L8Z A;  1E7J A;  1HRY A;  4NNU A;  1WXL A;  1L8Y A;  2D7L A;  1J3C A;  1J3X A;  2CRJ A;  4S2Q D;  1HME A;  2YUK A;  2GZK A;  3U2B C;  2YQI A;  2LE4 A;  4EUW A;  2CTO A;  1CG7 A;  1J3D A;  1K99 A;  4A3N A;  2YUL A;  3FGH A;  1HRZ A;  1J47 A;  1AAB A;  1NHN A;  2RTU A;  1HMA A;  2E6O A;  2CS1 A;  1HSM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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