4F8BA

Crystal structure of the covalent thioimide intermediate of unimodular nitrile reductase quef
Total Genus 41
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
139
structure length
139
Chain Sequence
NYLFEYAPDVLESFPNKHVNRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPDEKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEVWGKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis of biological nitrile reduction.
pubmed doi rcsb
molecule keywords NADPH-dependent 7-cyano-7-deazaguanine reductase
molecule tags Oxidoreductase
source organism Bacillus subtilis subsp. subtilis
total genus 41
structure length 139
sequence length 139
chains with identical sequence B, C, D, E
ec nomenclature ec 1.7.1.13: PreQ(1) synthase.
pdb deposition date 2012-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14489 QueF QueF-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1130.10 Alpha Beta 2-Layer Sandwich GTP Cyclohydrolase I, domain 2 GTP Cyclohydrolase I, domain 2 4f8bA00
2O90A 3UXVA 4UQFA 3BP1A 1WUQA 1NBUA 1WPLA 1N3SA 1WURA 1Z9WA 2NM3A 4AEYA 1RS4A 1DHNA 2DHNA 1WM9A 1NBUC 1RSIA 2NM2A 1GTPA 1RRIA 1SQLA 1IS7A 1N3TA 1RRWA 3RZPA 4GHMA 4F8BA 3O1KA 3R2EA 4FGCA 1RSDA 3UXJA 1IS8A 1A8RA 1A9CA 5F3MA 1RS2A 3V9OA 4DU6A 3S19A 5FARA 1FBXA 1NBUB 1FB1A 1N3RA 1RRYA 2CG8A 1U68A 4IQIA 3RJ4A 1B9LA
chains in the Genus database with same CATH superfamily
2O90A 3UXVA 4UQFA 3BP1A 1WUQA 1NBUA 1WPLA 1N3SA 1WURA 1Z9WA 2NM3A 4AEYA 1RS4A 1DHNA 2DHNA 1WM9A 1NBUC 1RSIA 2NM2A 1GTPA 1RRIA 1SQLA 1IS7A 1N3TA 1RRWA 3RZPA 4GHMA 4F8BA 3O1KA 3R2EA 4FGCA 1RSDA 3UXJA 1IS8A 1A8RA 1A9CA 5F3MA 1RS2A 3V9OA 4DU6A 3S19A 5FARA 1FBXA 1NBUB 1FB1A 1N3RA 1RRYA 2CG8A 1U68A 4IQIA 3RJ4A 1B9LA
chains in the Genus database with same CATH topology
2O90A 3UXVA 4UQFA 3BP1A 1WUQA 1NBUA 1WPLA 1N3SA 1WURA 1Z9WA 2NM3A 4AEYA 1RS4A 1DHNA 2DHNA 1WM9A 1NBUC 1RSIA 2NM2A 1GTPA 1RRIA 1SQLA 1IS7A 1N3TA 1RRWA 3RZPA 4GHMA 4F8BA 3O1KA 3R2EA 4FGCA 1RSDA 3UXJA 1IS8A 1A8RA 1A9CA 5F3MA 1RS2A 3V9OA 4DU6A 3S19A 5FARA 1FBXA 1NBUB 1FB1A 1N3RA 1RRYA 2CG8A 1U68A 4IQIA 3RJ4A 1B9LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O90 A;  3UXV A;  4UQF A;  3BP1 A;  1WUQ A;  1NBU A;  1WPL A;  1N3S A;  1WUR A;  1Z9W A;  2NM3 A;  4AEY A;  1RS4 A;  1DHN A;  2DHN A;  1WM9 A;  1NBU C;  1RSI A;  2NM2 A;  1GTP A;  1RRI A;  1SQL A;  1IS7 A;  1N3T A;  1RRW A;  3RZP A;  4GHM A;  4F8B A;  3O1K A;  3R2E A;  4FGC A;  1RSD A;  3UXJ A;  1IS8 A;  1A8R A;  1A9C A;  5F3M A;  1RS2 A;  3V9O A;  4DU6 A;  3S19 A;  5FAR A;  1FBX A;  1NBU B;  1FB1 A;  1N3R A;  1RRY A;  2CG8 A;  1U68 A;  4IQI A;  3RJ4 A;  1B9L A; 
#chains in the Genus database with same CATH topology
 2O90 A;  3UXV A;  4UQF A;  3BP1 A;  1WUQ A;  1NBU A;  1WPL A;  1N3S A;  1WUR A;  1Z9W A;  2NM3 A;  4AEY A;  1RS4 A;  1DHN A;  2DHN A;  1WM9 A;  1NBU C;  1RSI A;  2NM2 A;  1GTP A;  1RRI A;  1SQL A;  1IS7 A;  1N3T A;  1RRW A;  3RZP A;  4GHM A;  4F8B A;  3O1K A;  3R2E A;  4FGC A;  1RSD A;  3UXJ A;  1IS8 A;  1A8R A;  1A9C A;  5F3M A;  1RS2 A;  3V9O A;  4DU6 A;  3S19 A;  5FAR A;  1FBX A;  1NBU B;  1FB1 A;  1N3R A;  1RRY A;  2CG8 A;  1U68 A;  4IQI A;  3RJ4 A;  1B9L A; 
#chains in the Genus database with same CATH homology
 2O90 A;  3UXV A;  4UQF A;  3BP1 A;  1WUQ A;  1NBU A;  1WPL A;  1N3S A;  1WUR A;  1Z9W A;  2NM3 A;  4AEY A;  1RS4 A;  1DHN A;  2DHN A;  1WM9 A;  1NBU C;  1RSI A;  2NM2 A;  1GTP A;  1RRI A;  1SQL A;  1IS7 A;  1N3T A;  1RRW A;  3RZP A;  4GHM A;  4F8B A;  3O1K A;  3R2E A;  4FGC A;  1RSD A;  3UXJ A;  1IS8 A;  1A8R A;  1A9C A;  5F3M A;  1RS2 A;  3V9O A;  4DU6 A;  3S19 A;  5FAR A;  1FBX A;  1NBU B;  1FB1 A;  1N3R A;  1RRY A;  2CG8 A;  1U68 A;  4IQI A;  3RJ4 A;  1B9L A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...