4FG6A

Structure of ecclc e148a mutant in glutamate
Total Genus 173
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
173
sequence length
444
structure length
444
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGRAGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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connected with : NaN
publication title Molecular mechanism of proton transport in CLC Cl-/H+ exchange transporters.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli k-12
molecule keywords H(+)/Cl(-) exchange transporter ClcA
total genus 173
structure length 444
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-06-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 4fg6A00
3EJZA 2R9HA 2HTLA 2EXWA 4KJWA 2H2SA 4KK6A 4FG6A 2HT3A 1KPLA 2FEEA 1OTTA 4MQXA 2EXYA 2EZ0A 4KJQA 4KK8A 3NMOA 2FEDA 2H2PA 5HD8A 2HT2A 4KKBA 2FECA 4LOUA 4KKAA 4KK9A 1OTSA 4KK5A 3Q17A 4ENEA 3ND0A 3ORGA 2HT4A 4KKCA 4FTPA 2HTKA 1OTUA 3EJYA 2HLFA 4KKLA 4KJPA 1KPKA 3DETA
chains in the Genus database with same CATH superfamily
3EJZA 2R9HA 2HTLA 2EXWA 4KJWA 2H2SA 4KK6A 4FG6A 2HT3A 1KPLA 2FEEA 1OTTA 4MQXA 2EXYA 2EZ0A 4KJQA 4KK8A 3NMOA 2FEDA 2H2PA 5HD8A 2HT2A 4KKBA 2FECA 4LOUA 4KKAA 4KK9A 1OTSA 4KK5A 3Q17A 4ENEA 3ND0A 3ORGA 2HT4A 4KKCA 4FTPA 2HTKA 1OTUA 3EJYA 2HLFA 4KKLA 4KJPA 1KPKA 3DETA
chains in the Genus database with same CATH topology
3EJZA 2R9HA 2HTLA 2EXWA 4KJWA 2H2SA 4KK6A 4FG6A 2HT3A 1KPLA 2FEEA 1OTTA 4MQXA 2EXYA 2EZ0A 4KJQA 4KK8A 3NMOA 2FEDA 2H2PA 5HD8A 2HT2A 4KKBA 2FECA 4LOUA 4KKAA 4KK9A 1OTSA 4KK5A 3Q17A 4ENEA 3ND0A 3ORGA 2HT4A 4KKCA 4FTPA 2HTKA 1OTUA 3EJYA 2HLFA 4KKLA 4KJPA 1KPKA 3DETA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EJZ A;  2R9H A;  2HTL A;  2EXW A;  4KJW A;  2H2S A;  4KK6 A;  4FG6 A;  2HT3 A;  1KPL A;  2FEE A;  1OTT A;  4MQX A;  2EXY A;  2EZ0 A;  4KJQ A;  4KK8 A;  3NMO A;  2FED A;  2H2P A;  5HD8 A;  2HT2 A;  4KKB A;  2FEC A;  4LOU A;  4KKA A;  4KK9 A;  1OTS A;  4KK5 A;  3Q17 A;  4ENE A;  3ND0 A;  3ORG A;  2HT4 A;  4KKC A;  4FTP A;  2HTK A;  1OTU A;  3EJY A;  2HLF A;  4KKL A;  4KJP A;  1KPK A;  3DET A; 
#chains in the Genus database with same CATH topology
 3EJZ A;  2R9H A;  2HTL A;  2EXW A;  4KJW A;  2H2S A;  4KK6 A;  4FG6 A;  2HT3 A;  1KPL A;  2FEE A;  1OTT A;  4MQX A;  2EXY A;  2EZ0 A;  4KJQ A;  4KK8 A;  3NMO A;  2FED A;  2H2P A;  5HD8 A;  2HT2 A;  4KKB A;  2FEC A;  4LOU A;  4KKA A;  4KK9 A;  1OTS A;  4KK5 A;  3Q17 A;  4ENE A;  3ND0 A;  3ORG A;  2HT4 A;  4KKC A;  4FTP A;  2HTK A;  1OTU A;  3EJY A;  2HLF A;  4KKL A;  4KJP A;  1KPK A;  3DET A; 
#chains in the Genus database with same CATH homology
 3EJZ A;  2R9H A;  2HTL A;  2EXW A;  4KJW A;  2H2S A;  4KK6 A;  4FG6 A;  2HT3 A;  1KPL A;  2FEE A;  1OTT A;  4MQX A;  2EXY A;  2EZ0 A;  4KJQ A;  4KK8 A;  3NMO A;  2FED A;  2H2P A;  5HD8 A;  2HT2 A;  4KKB A;  2FEC A;  4LOU A;  4KKA A;  4KK9 A;  1OTS A;  4KK5 A;  3Q17 A;  4ENE A;  3ND0 A;  3ORG A;  2HT4 A;  4KKC A;  4FTP A;  2HTK A;  1OTU A;  3EJY A;  2HLF A;  4KKL A;  4KJP A;  1KPK A;  3DET A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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