4IOAH

Crystal structure of compound 4e bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
134
structure length
134
Chain Sequence
MIMPQSRLDVADNSGAREIMCIRVLNSGIGGKGLTTGGGGNKRYAHVGDIIVASVKDAAPRGAVKAGDVVKAVVVRTSHAIKRADGSTIRFDRNAAVIINNQGEPRGTRVFGPVARELRDRRFMKIVSLAPEVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 30
structure length 134
sequence length 134
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00238 Ribosomal_L14 Ribosomal protein L14p/L23e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.150.20 Mainly Beta Beta Barrel Ribosomal Protein L14 Ribosomal protein L14 4ioaH00
3CCLK 1NJIL 5DM6H 4V19O 4WFNH 3CCRK 2OTLK 2OTJK 3CCJK 1VQ6K 4WCEH 3CCVK 3CCEK 1VQOK 1JJ2J 4IOCH 5AN9E 1S72K 3I55K 5H1SM 1YJ9K 3CXCJ 4WFAH 2ZJPH 1QVGJ 1VQ8K 1YI2K 3CCSK 3G6EK 3CD6K 1VQNK 3CPWJ 3G71K 1QVFJ 1VQ5K 1K73L 1VQPK 1Q82L 3CMEK 2QEXK 1Q81L 1VQ9K 3PIOH 1YIJK 4WFBH 3PIPH 4IOAH 4UY8K 1Q7YL 1M90L 5GADL 1VQ4K 4U67H 3G4SK 5GAHL 1M1KL 5DM7H 3CF5H 1Q86L 1YHQK 4WF9H 4IO9H 3DLLH 3CC2K 2QA4K 1VQLK 3OW2J 5HL7H 5GAGL 1VQMK 5MLCM 3CMAK 2ZJQH 3J7ZK 2ZJRH 1W2BJ 1K8AL 3CCMK 1K9ML 3CC7K 3CCQK 1N8RL 3J7YL 1WHIA 3I56K 5JVHH 1KC8L 3CC4K 1KD1L 1VQKK 3CCUK 1YITK 1KQSJ 5JVGH 5GAEL 1YJWK 1YJNK 1VQ7K
chains in the Genus database with same CATH superfamily
3CCLK 1NJIL 5DM6H 4V19O 4WFNH 3CCRK 2OTLK 2OTJK 3CCJK 1VQ6K 4WCEH 3CCVK 3CCEK 1VQOK 1JJ2J 4IOCH 5AN9E 1S72K 3I55K 5H1SM 1YJ9K 3CXCJ 4WFAH 2ZJPH 1QVGJ 1VQ8K 1YI2K 3CCSK 3G6EK 3CD6K 1VQNK 3CPWJ 3G71K 1QVFJ 1VQ5K 1K73L 1VQPK 1Q82L 3CMEK 2QEXK 1Q81L 1VQ9K 3PIOH 1YIJK 4WFBH 3PIPH 4IOAH 4UY8K 1Q7YL 1M90L 5GADL 1VQ4K 4U67H 3G4SK 5GAHL 1M1KL 5DM7H 3CF5H 1Q86L 1YHQK 4WF9H 4IO9H 3DLLH 3CC2K 2QA4K 1VQLK 3OW2J 5HL7H 5GAGL 1VQMK 5MLCM 3CMAK 2ZJQH 3J7ZK 2ZJRH 1W2BJ 1K8AL 3CCMK 1K9ML 3CC7K 3CCQK 1N8RL 3J7YL 1WHIA 3I56K 5JVHH 1KC8L 3CC4K 1KD1L 1VQKK 3CCUK 1YITK 1KQSJ 5JVGH 5GAEL 1YJWK 1YJNK 1VQ7K
chains in the Genus database with same CATH topology
3CCLK 1NJIL 5DM6H 4V19O 4WFNH 3CCRK 2OTLK 2OTJK 3CCJK 1VQ6K 4WCEH 3CCVK 3CCEK 1VQOK 1JJ2J 4IOCH 5AN9E 1S72K 3I55K 5H1SM 1YJ9K 3CXCJ 4WFAH 2ZJPH 1QVGJ 1VQ8K 1YI2K 3CCSK 3G6EK 3CD6K 1VQNK 3CPWJ 3G71K 1QVFJ 1VQ5K 1K73L 1VQPK 1Q82L 3CMEK 2QEXK 1Q81L 1VQ9K 3PIOH 1YIJK 4WFBH 3PIPH 4IOAH 4UY8K 1Q7YL 1M90L 5GADL 1VQ4K 4U67H 3G4SK 5GAHL 1M1KL 5DM7H 3CF5H 1Q86L 1YHQK 4WF9H 4IO9H 3DLLH 3CC2K 2QA4K 1VQLK 3OW2J 5HL7H 5GAGL 1VQMK 5MLCM 3CMAK 2ZJQH 3J7ZK 2ZJRH 1W2BJ 1K8AL 3CCMK 1K9ML 3CC7K 3CCQK 1N8RL 3J7YL 1WHIA 3I56K 5JVHH 1KC8L 3CC4K 1KD1L 1VQKK 3CCUK 1YITK 1KQSJ 5JVGH 5GAEL 1YJWK 1YJNK 1VQ7K
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCL K;  1NJI L;  5DM6 H;  4V19 O;  4WFN H;  3CCR K;  2OTL K;  2OTJ K;  3CCJ K;  1VQ6 K;  4WCE H;  3CCV K;  3CCE K;  1VQO K;  1JJ2 J;  4IOC H;  5AN9 E;  1S72 K;  3I55 K;  5H1S M;  1YJ9 K;  3CXC J;  4WFA H;  2ZJP H;  1QVG J;  1VQ8 K;  1YI2 K;  3CCS K;  3G6E K;  3CD6 K;  1VQN K;  3CPW J;  3G71 K;  1QVF J;  1VQ5 K;  1K73 L;  1VQP K;  1Q82 L;  3CME K;  2QEX K;  1Q81 L;  1VQ9 K;  3PIO H;  1YIJ K;  4WFB H;  3PIP H;  4IOA H;  4UY8 K;  1Q7Y L;  1M90 L;  5GAD L;  1VQ4 K;  4U67 H;  3G4S K;  5GAH L;  1M1K L;  5DM7 H;  3CF5 H;  1Q86 L;  1YHQ K;  4WF9 H;  4IO9 H;  3DLL H;  3CC2 K;  2QA4 K;  1VQL K;  3OW2 J;  5HL7 H;  5GAG L;  1VQM K;  5MLC M;  3CMA K;  2ZJQ H;  3J7Z K;  2ZJR H;  1W2B J;  1K8A L;  3CCM K;  1K9M L;  3CC7 K;  3CCQ K;  1N8R L;  3J7Y L;  1WHI A;  3I56 K;  5JVH H;  1KC8 L;  3CC4 K;  1KD1 L;  1VQK K;  3CCU K;  1YIT K;  1KQS J;  5JVG H;  5GAE L;  1YJW K;  1YJN K;  1VQ7 K; 
#chains in the Genus database with same CATH topology
 3CCL K;  1NJI L;  5DM6 H;  4V19 O;  4WFN H;  3CCR K;  2OTL K;  2OTJ K;  3CCJ K;  1VQ6 K;  4WCE H;  3CCV K;  3CCE K;  1VQO K;  1JJ2 J;  4IOC H;  5AN9 E;  1S72 K;  3I55 K;  5H1S M;  1YJ9 K;  3CXC J;  4WFA H;  2ZJP H;  1QVG J;  1VQ8 K;  1YI2 K;  3CCS K;  3G6E K;  3CD6 K;  1VQN K;  3CPW J;  3G71 K;  1QVF J;  1VQ5 K;  1K73 L;  1VQP K;  1Q82 L;  3CME K;  2QEX K;  1Q81 L;  1VQ9 K;  3PIO H;  1YIJ K;  4WFB H;  3PIP H;  4IOA H;  4UY8 K;  1Q7Y L;  1M90 L;  5GAD L;  1VQ4 K;  4U67 H;  3G4S K;  5GAH L;  1M1K L;  5DM7 H;  3CF5 H;  1Q86 L;  1YHQ K;  4WF9 H;  4IO9 H;  3DLL H;  3CC2 K;  2QA4 K;  1VQL K;  3OW2 J;  5HL7 H;  5GAG L;  1VQM K;  5MLC M;  3CMA K;  2ZJQ H;  3J7Z K;  2ZJR H;  1W2B J;  1K8A L;  3CCM K;  1K9M L;  3CC7 K;  3CCQ K;  1N8R L;  3J7Y L;  1WHI A;  3I56 K;  5JVH H;  1KC8 L;  3CC4 K;  1KD1 L;  1VQK K;  3CCU K;  1YIT K;  1KQS J;  5JVG H;  5GAE L;  1YJW K;  1YJN K;  1VQ7 K; 
#chains in the Genus database with same CATH homology
 3CCL K;  1NJI L;  5DM6 H;  4V19 O;  4WFN H;  3CCR K;  2OTL K;  2OTJ K;  3CCJ K;  1VQ6 K;  4WCE H;  3CCV K;  3CCE K;  1VQO K;  1JJ2 J;  4IOC H;  5AN9 E;  1S72 K;  3I55 K;  5H1S M;  1YJ9 K;  3CXC J;  4WFA H;  2ZJP H;  1QVG J;  1VQ8 K;  1YI2 K;  3CCS K;  3G6E K;  3CD6 K;  1VQN K;  3CPW J;  3G71 K;  1QVF J;  1VQ5 K;  1K73 L;  1VQP K;  1Q82 L;  3CME K;  2QEX K;  1Q81 L;  1VQ9 K;  3PIO H;  1YIJ K;  4WFB H;  3PIP H;  4IOA H;  4UY8 K;  1Q7Y L;  1M90 L;  5GAD L;  1VQ4 K;  4U67 H;  3G4S K;  5GAH L;  1M1K L;  5DM7 H;  3CF5 H;  1Q86 L;  1YHQ K;  4WF9 H;  4IO9 H;  3DLL H;  3CC2 K;  2QA4 K;  1VQL K;  3OW2 J;  5HL7 H;  5GAG L;  1VQM K;  5MLC M;  3CMA K;  2ZJQ H;  3J7Z K;  2ZJR H;  1W2B J;  1K8A L;  3CCM K;  1K9M L;  3CC7 K;  3CCQ K;  1N8R L;  3J7Y L;  1WHI A;  3I56 K;  5JVH H;  1KC8 L;  3CC4 K;  1KD1 L;  1VQK K;  3CCU K;  1YIT K;  1KQS J;  5JVG H;  5GAE L;  1YJW K;  1YJN K;  1VQ7 K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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