4KJQA

Structure of the clc-ec1 deltanc construct in 100mm fluoride
Total Genus 167
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
167
sequence length
444
structure length
444
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
pubmed doi rcsb
molecule keywords H(+)/Cl(-) exchange transporter ClcA
molecule tags Tranport protein, membrane protein
source organism Escherichia coli
total genus 167
structure length 444
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 4kjqA00
4KKCA 2HT2A 2HTKA 4KKAA 2HLFA 1KPLA 4KK6A 4LOUA 2FECA 4ENEA 4FTPA 4KJPA 1KPKA 3EJYA 3ORGA 2H2SA 3EJZA 4KK9A 1OTSA 2EXYA 2HT3A 3ND0A 1OTTA 3DETA 5HD8A 4KKLA 4KJWA 4KK5A 2EZ0A 3NMOA 4KJQA 2R9HA 2FEEA 3Q17A 2H2PA 2HTLA 1OTUA 2HT4A 2EXWA 4KK8A 4KKBA 2FEDA 4FG6A 4MQXA
chains in the Genus database with same CATH superfamily
4KKCA 2HT2A 2HTKA 4KKAA 2HLFA 1KPLA 4KK6A 4LOUA 2FECA 4ENEA 4FTPA 4KJPA 1KPKA 3EJYA 3ORGA 2H2SA 3EJZA 4KK9A 1OTSA 2EXYA 2HT3A 3ND0A 1OTTA 3DETA 5HD8A 4KKLA 4KJWA 4KK5A 2EZ0A 3NMOA 4KJQA 2R9HA 2FEEA 3Q17A 2H2PA 2HTLA 1OTUA 2HT4A 2EXWA 4KK8A 4KKBA 2FEDA 4FG6A 4MQXA
chains in the Genus database with same CATH topology
4KKCA 2HT2A 2HTKA 4KKAA 2HLFA 1KPLA 4KK6A 4LOUA 2FECA 4ENEA 4FTPA 4KJPA 1KPKA 3EJYA 3ORGA 2H2SA 3EJZA 4KK9A 1OTSA 2EXYA 2HT3A 3ND0A 1OTTA 3DETA 5HD8A 4KKLA 4KJWA 4KK5A 2EZ0A 3NMOA 4KJQA 2R9HA 2FEEA 3Q17A 2H2PA 2HTLA 1OTUA 2HT4A 2EXWA 4KK8A 4KKBA 2FEDA 4FG6A 4MQXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KKC A;  2HT2 A;  2HTK A;  4KKA A;  2HLF A;  1KPL A;  4KK6 A;  4LOU A;  2FEC A;  4ENE A;  4FTP A;  4KJP A;  1KPK A;  3EJY A;  3ORG A;  2H2S A;  3EJZ A;  4KK9 A;  1OTS A;  2EXY A;  2HT3 A;  3ND0 A;  1OTT A;  3DET A;  5HD8 A;  4KKL A;  4KJW A;  4KK5 A;  2EZ0 A;  3NMO A;  4KJQ A;  2R9H A;  2FEE A;  3Q17 A;  2H2P A;  2HTL A;  1OTU A;  2HT4 A;  2EXW A;  4KK8 A;  4KKB A;  2FED A;  4FG6 A;  4MQX A; 
#chains in the Genus database with same CATH topology
 4KKC A;  2HT2 A;  2HTK A;  4KKA A;  2HLF A;  1KPL A;  4KK6 A;  4LOU A;  2FEC A;  4ENE A;  4FTP A;  4KJP A;  1KPK A;  3EJY A;  3ORG A;  2H2S A;  3EJZ A;  4KK9 A;  1OTS A;  2EXY A;  2HT3 A;  3ND0 A;  1OTT A;  3DET A;  5HD8 A;  4KKL A;  4KJW A;  4KK5 A;  2EZ0 A;  3NMO A;  4KJQ A;  2R9H A;  2FEE A;  3Q17 A;  2H2P A;  2HTL A;  1OTU A;  2HT4 A;  2EXW A;  4KK8 A;  4KKB A;  2FED A;  4FG6 A;  4MQX A; 
#chains in the Genus database with same CATH homology
 4KKC A;  2HT2 A;  2HTK A;  4KKA A;  2HLF A;  1KPL A;  4KK6 A;  4LOU A;  2FEC A;  4ENE A;  4FTP A;  4KJP A;  1KPK A;  3EJY A;  3ORG A;  2H2S A;  3EJZ A;  4KK9 A;  1OTS A;  2EXY A;  2HT3 A;  3ND0 A;  1OTT A;  3DET A;  5HD8 A;  4KKL A;  4KJW A;  4KK5 A;  2EZ0 A;  3NMO A;  4KJQ A;  2R9H A;  2FEE A;  3Q17 A;  2H2P A;  2HTL A;  1OTU A;  2HT4 A;  2EXW A;  4KK8 A;  4KKB A;  2FED A;  4FG6 A;  4MQX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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