4KK5A

Structure of the clc-ec1 deltanc construct in 20mm fluoride and 20mm bromide
Total Genus 183
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
183
sequence length
444
structure length
444
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords H(+)/Cl(-) exchange transporter ClcA
total genus 183
structure length 444
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 4kk5A00
2FEDA 3NMOA 4KKLA 4MQXA 4FG6A 1KPLA 2FECA 1OTTA 2H2SA 2H2PA 3EJYA 3DETA 2EXYA 2EXWA 2R9HA 4KJWA 2HT3A 4KK6A 4ENEA 3ORGA 1OTSA 2HTLA 2HLFA 4KKCA 2FEEA 3ND0A 1KPKA 4KK8A 4KKAA 4KK5A 2HT4A 2HT2A 4KKBA 2EZ0A 4KJQA 2HTKA 5HD8A 3Q17A 4KK9A 4KJPA 4FTPA 1OTUA 4LOUA 3EJZA
chains in the Genus database with same CATH superfamily
2FEDA 3NMOA 4KKLA 4MQXA 4FG6A 1KPLA 2FECA 1OTTA 2H2SA 2H2PA 3EJYA 3DETA 2EXYA 2EXWA 2R9HA 4KJWA 2HT3A 4KK6A 4ENEA 3ORGA 1OTSA 2HTLA 2HLFA 4KKCA 2FEEA 3ND0A 1KPKA 4KK8A 4KKAA 4KK5A 2HT4A 2HT2A 4KKBA 2EZ0A 4KJQA 2HTKA 5HD8A 3Q17A 4KK9A 4KJPA 4FTPA 1OTUA 4LOUA 3EJZA
chains in the Genus database with same CATH topology
2FEDA 3NMOA 4KKLA 4MQXA 4FG6A 1KPLA 2FECA 1OTTA 2H2SA 2H2PA 3EJYA 3DETA 2EXYA 2EXWA 2R9HA 4KJWA 2HT3A 4KK6A 4ENEA 3ORGA 1OTSA 2HTLA 2HLFA 4KKCA 2FEEA 3ND0A 1KPKA 4KK8A 4KKAA 4KK5A 2HT4A 2HT2A 4KKBA 2EZ0A 4KJQA 2HTKA 5HD8A 3Q17A 4KK9A 4KJPA 4FTPA 1OTUA 4LOUA 3EJZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FED A;  3NMO A;  4KKL A;  4MQX A;  4FG6 A;  1KPL A;  2FEC A;  1OTT A;  2H2S A;  2H2P A;  3EJY A;  3DET A;  2EXY A;  2EXW A;  2R9H A;  4KJW A;  2HT3 A;  4KK6 A;  4ENE A;  3ORG A;  1OTS A;  2HTL A;  2HLF A;  4KKC A;  2FEE A;  3ND0 A;  1KPK A;  4KK8 A;  4KKA A;  4KK5 A;  2HT4 A;  2HT2 A;  4KKB A;  2EZ0 A;  4KJQ A;  2HTK A;  5HD8 A;  3Q17 A;  4KK9 A;  4KJP A;  4FTP A;  1OTU A;  4LOU A;  3EJZ A; 
#chains in the Genus database with same CATH topology
 2FED A;  3NMO A;  4KKL A;  4MQX A;  4FG6 A;  1KPL A;  2FEC A;  1OTT A;  2H2S A;  2H2P A;  3EJY A;  3DET A;  2EXY A;  2EXW A;  2R9H A;  4KJW A;  2HT3 A;  4KK6 A;  4ENE A;  3ORG A;  1OTS A;  2HTL A;  2HLF A;  4KKC A;  2FEE A;  3ND0 A;  1KPK A;  4KK8 A;  4KKA A;  4KK5 A;  2HT4 A;  2HT2 A;  4KKB A;  2EZ0 A;  4KJQ A;  2HTK A;  5HD8 A;  3Q17 A;  4KK9 A;  4KJP A;  4FTP A;  1OTU A;  4LOU A;  3EJZ A; 
#chains in the Genus database with same CATH homology
 2FED A;  3NMO A;  4KKL A;  4MQX A;  4FG6 A;  1KPL A;  2FEC A;  1OTT A;  2H2S A;  2H2P A;  3EJY A;  3DET A;  2EXY A;  2EXW A;  2R9H A;  4KJW A;  2HT3 A;  4KK6 A;  4ENE A;  3ORG A;  1OTS A;  2HTL A;  2HLF A;  4KKC A;  2FEE A;  3ND0 A;  1KPK A;  4KK8 A;  4KKA A;  4KK5 A;  2HT4 A;  2HT2 A;  4KKB A;  2EZ0 A;  4KJQ A;  2HTK A;  5HD8 A;  3Q17 A;  4KK9 A;  4KJP A;  4FTP A;  1OTU A;  4LOU A;  3EJZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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