4KK6A

Structure of clc-ec1 deltanc construct in 20mm bromide
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
443
structure length
443
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords H(+)/Cl(-) exchange transporter ClcA
total genus 166
structure length 443
sequence length 443
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 4kk6A00
4MQXA 4KKLA 4ENEA 1KPLA 4KK5A 2FEDA 2R9HA 2FECA 2EZ0A 4LOUA 2HT4A 3DETA 2HLFA 4KJQA 3EJZA 1OTUA 3ND0A 3ORGA 4FG6A 4KJPA 4KKAA 4KK6A 4KK8A 1OTTA 2H2SA 4KKBA 3Q17A 4KJWA 4KKCA 1OTSA 1KPKA 2EXYA 2HTKA 2H2PA 4KK9A 3EJYA 3NMOA 2EXWA 2FEEA 5HD8A 2HTLA 2HT2A 4FTPA 2HT3A
chains in the Genus database with same CATH superfamily
4MQXA 4KKLA 4ENEA 1KPLA 4KK5A 2FEDA 2R9HA 2FECA 2EZ0A 4LOUA 2HT4A 3DETA 2HLFA 4KJQA 3EJZA 1OTUA 3ND0A 3ORGA 4FG6A 4KJPA 4KKAA 4KK6A 4KK8A 1OTTA 2H2SA 4KKBA 3Q17A 4KJWA 4KKCA 1OTSA 1KPKA 2EXYA 2HTKA 2H2PA 4KK9A 3EJYA 3NMOA 2EXWA 2FEEA 5HD8A 2HTLA 2HT2A 4FTPA 2HT3A
chains in the Genus database with same CATH topology
4MQXA 4KKLA 4ENEA 1KPLA 4KK5A 2FEDA 2R9HA 2FECA 2EZ0A 4LOUA 2HT4A 3DETA 2HLFA 4KJQA 3EJZA 1OTUA 3ND0A 3ORGA 4FG6A 4KJPA 4KKAA 4KK6A 4KK8A 1OTTA 2H2SA 4KKBA 3Q17A 4KJWA 4KKCA 1OTSA 1KPKA 2EXYA 2HTKA 2H2PA 4KK9A 3EJYA 3NMOA 2EXWA 2FEEA 5HD8A 2HTLA 2HT2A 4FTPA 2HT3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MQX A;  4KKL A;  4ENE A;  1KPL A;  4KK5 A;  2FED A;  2R9H A;  2FEC A;  2EZ0 A;  4LOU A;  2HT4 A;  3DET A;  2HLF A;  4KJQ A;  3EJZ A;  1OTU A;  3ND0 A;  3ORG A;  4FG6 A;  4KJP A;  4KKA A;  4KK6 A;  4KK8 A;  1OTT A;  2H2S A;  4KKB A;  3Q17 A;  4KJW A;  4KKC A;  1OTS A;  1KPK A;  2EXY A;  2HTK A;  2H2P A;  4KK9 A;  3EJY A;  3NMO A;  2EXW A;  2FEE A;  5HD8 A;  2HTL A;  2HT2 A;  4FTP A;  2HT3 A; 
#chains in the Genus database with same CATH topology
 4MQX A;  4KKL A;  4ENE A;  1KPL A;  4KK5 A;  2FED A;  2R9H A;  2FEC A;  2EZ0 A;  4LOU A;  2HT4 A;  3DET A;  2HLF A;  4KJQ A;  3EJZ A;  1OTU A;  3ND0 A;  3ORG A;  4FG6 A;  4KJP A;  4KKA A;  4KK6 A;  4KK8 A;  1OTT A;  2H2S A;  4KKB A;  3Q17 A;  4KJW A;  4KKC A;  1OTS A;  1KPK A;  2EXY A;  2HTK A;  2H2P A;  4KK9 A;  3EJY A;  3NMO A;  2EXW A;  2FEE A;  5HD8 A;  2HTL A;  2HT2 A;  4FTP A;  2HT3 A; 
#chains in the Genus database with same CATH homology
 4MQX A;  4KKL A;  4ENE A;  1KPL A;  4KK5 A;  2FED A;  2R9H A;  2FEC A;  2EZ0 A;  4LOU A;  2HT4 A;  3DET A;  2HLF A;  4KJQ A;  3EJZ A;  1OTU A;  3ND0 A;  3ORG A;  4FG6 A;  4KJP A;  4KKA A;  4KK6 A;  4KK8 A;  1OTT A;  2H2S A;  4KKB A;  3Q17 A;  4KJW A;  4KKC A;  1OTS A;  1KPK A;  2EXY A;  2HTK A;  2H2P A;  4KK9 A;  3EJY A;  3NMO A;  2EXW A;  2FEE A;  5HD8 A;  2HTL A;  2HT2 A;  4FTP A;  2HT3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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